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The map label for this gene is murG [H]

Identifier: 145296120

GI number: 145296120

Start: 2246650

End: 2247768

Strand: Reverse

Name: murG [H]

Synonym: cgR_2040

Alternate gene names: 145296120

Gene position: 2247768-2246650 (Counterclockwise)

Preceding gene: 145296121

Following gene: 145296119

Centisome position: 67.82

GC content: 56.93

Gene sequence:

>1119_bases
GTGAAATCAGGAGAACTACGAATAAAGATGGCTAACTCCCCAAAACCCATGCGGGTTGTCGTTGCTGGTGGCGGTACCGC
AGGACATATTGAGCCTGCGTTGGCAGTGGCTGAAGCGCTGCGCGACAAGCACGGTGCAACAGTTTCGGCTTTAGGTACTG
CTCGTGGTTTGGAAACAACCCTGGTGCCTGATCGTGGGTTTGAGCTTCATCTCATCGAGCCGGTTCCAGTCCCACGCAAG
CCCAATATGGATTTGTTGAAGCTCCCATTCCGGGTAGCTAAGGCATTAGGCCAAGCACGCAAGGCACTGAAGGACACAGA
CGCTCAAGCGGTCATCGGCTTTGGCGGTTATGTATCTGCTCCGGCTTATATGGCGGCGAAGTCTTTGGGCTTGCCATTTT
TTGTCCACGAAGCCAACGCCCGTGCAGGCATGGCCAACAAATTGGGCGTCAAGCTCGGTGGCGTTGGCCTTAATGCTGTT
GCTGGTTCCGGCATGGAAGGCGACGTGGTGGGCATTCCGATTCGTGCTGTTTTAAGTGGCGCGCGGGATGAGTCCGCAGC
TGACCGAGCCAGGGACACTTGGGGTTTGGACAAGGATCGCCAAACCATTTTTGTCACCGGTGGTTCGCAGGGCTCTGTGA
GTATCAACAAGGCCGTCGAGCAAGCTGTAGATCAGCTGGTGGAGGCAGGTTTCCAGGTGCTCCACGCCGTGGGTAAGAAA
AACGAGTTGCCTGCAGCGAAACCCGGCTACCATCCCGTTCCGTTCATCGACGATATGCAGGCTGCCTACACCGTTGCTGA
TCTTATCGTGTGCCGCTCCGGCGCGATGACGGTTGCAGAGGTCACCGCCGCCGGCGTCCCCGCGATTTATGTCCCGCTGC
CTCACGGCAACGGTGAGCAGGCTCTCAACGCCCAGGCTGTCATTAAAGCTGGTGCCGCGCGCCAGATCGACGACGCGGAC
TTCACCGCCCAGACGCTTATCGACGCCACCCTTGACATTCTCCTTCATCCCTCCACACACCAATCGATGTCGGACGCAGC
TAAAACCTCCACCGCAGGTAACGCGTCCACGGTGATTGCAGACATGATTGCTGCAACTATCAAAAGCCAACACAACTAA

Upstream 100 bases:

>100_bases
CAGCCGATCGCAGCGTTGATCGAAGTCGTCAAAGCAGGCCTACCGAGCGCCGTTCCGAGTCGCGCGATGATTGGCGTGAC
AACCGCAACCGCAGATAAAT

Downstream 100 bases:

>100_bases
AACGACCAGCTCAACGCAAAGGAATAGTTTAAAGGTGACCACTCCACACTTGGATTCTGCACAAGATATTGATCTGTCCC
GCGTCCACCTCATCGGTATT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MKSGELRIKMANSPKPMRVVVAGGGTAGHIEPALAVAEALRDKHGATVSALGTARGLETTLVPDRGFELHLIEPVPVPRK
PNMDLLKLPFRVAKALGQARKALKDTDAQAVIGFGGYVSAPAYMAAKSLGLPFFVHEANARAGMANKLGVKLGGVGLNAV
AGSGMEGDVVGIPIRAVLSGARDESAADRARDTWGLDKDRQTIFVTGGSQGSVSINKAVEQAVDQLVEAGFQVLHAVGKK
NELPAAKPGYHPVPFIDDMQAAYTVADLIVCRSGAMTVAEVTAAGVPAIYVPLPHGNGEQALNAQAVIKAGAARQIDDAD
FTAQTLIDATLDILLHPSTHQSMSDAAKTSTAGNASTVIADMIAATIKSQHN

Sequences:

>Translated_372_residues
MKSGELRIKMANSPKPMRVVVAGGGTAGHIEPALAVAEALRDKHGATVSALGTARGLETTLVPDRGFELHLIEPVPVPRK
PNMDLLKLPFRVAKALGQARKALKDTDAQAVIGFGGYVSAPAYMAAKSLGLPFFVHEANARAGMANKLGVKLGGVGLNAV
AGSGMEGDVVGIPIRAVLSGARDESAADRARDTWGLDKDRQTIFVTGGSQGSVSINKAVEQAVDQLVEAGFQVLHAVGKK
NELPAAKPGYHPVPFIDDMQAAYTVADLIVCRSGAMTVAEVTAAGVPAIYVPLPHGNGEQALNAQAVIKAGAARQIDDAD
FTAQTLIDATLDILLHPSTHQSMSDAAKTSTAGNASTVIADMIAATIKSQHN
>Mature_372_residues
MKSGELRIKMANSPKPMRVVVAGGGTAGHIEPALAVAEALRDKHGATVSALGTARGLETTLVPDRGFELHLIEPVPVPRK
PNMDLLKLPFRVAKALGQARKALKDTDAQAVIGFGGYVSAPAYMAAKSLGLPFFVHEANARAGMANKLGVKLGGVGLNAV
AGSGMEGDVVGIPIRAVLSGARDESAADRARDTWGLDKDRQTIFVTGGSQGSVSINKAVEQAVDQLVEAGFQVLHAVGKK
NELPAAKPGYHPVPFIDDMQAAYTVADLIVCRSGAMTVAEVTAAGVPAIYVPLPHGNGEQALNAQAVIKAGAARQIDDAD
FTAQTLIDATLDILLHPSTHQSMSDAAKTSTAGNASTVIADMIAATIKSQHN

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=358, Percent_Identity=35.195530726257, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 38495; Mature: 38495

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSGELRIKMANSPKPMRVVVAGGGTAGHIEPALAVAEALRDKHGATVSALGTARGLETT
CCCCCEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEHHCCCCCEEE
LVPDRGFELHLIEPVPVPRKPNMDLLKLPFRVAKALGQARKALKDTDAQAVIGFGGYVSA
ECCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHCC
PAYMAAKSLGLPFFVHEANARAGMANKLGVKLGGVGLNAVAGSGMEGDVVGIPIRAVLSG
CHHHHHHHCCCEEEEEECCCCCCCCHHCCEEECCCCCHHHCCCCCCCCEEECCHHHHHCC
ARDESAADRARDTWGLDKDRQTIFVTGGSQGSVSINKAVEQAVDQLVEAGFQVLHAVGKK
CCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
NELPAAKPGYHPVPFIDDMQAAYTVADLIVCRSGAMTVAEVTAAGVPAIYVPLPHGNGEQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCCCCH
ALNAQAVIKAGAARQIDDADFTAQTLIDATLDILLHPSTHQSMSDAAKTSTAGNASTVIA
HHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCCHHHHHH
DMIAATIKSQHN
HHHHHHHHHCCC
>Mature Secondary Structure
MKSGELRIKMANSPKPMRVVVAGGGTAGHIEPALAVAEALRDKHGATVSALGTARGLETT
CCCCCEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEHHCCCCCEEE
LVPDRGFELHLIEPVPVPRKPNMDLLKLPFRVAKALGQARKALKDTDAQAVIGFGGYVSA
ECCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHCC
PAYMAAKSLGLPFFVHEANARAGMANKLGVKLGGVGLNAVAGSGMEGDVVGIPIRAVLSG
CHHHHHHHCCCEEEEEECCCCCCCCHHCCEEECCCCCHHHCCCCCCCCEEECCHHHHHCC
ARDESAADRARDTWGLDKDRQTIFVTGGSQGSVSINKAVEQAVDQLVEAGFQVLHAVGKK
CCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
NELPAAKPGYHPVPFIDDMQAAYTVADLIVCRSGAMTVAEVTAAGVPAIYVPLPHGNGEQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCCCCH
ALNAQAVIKAGAARQIDDADFTAQTLIDATLDILLHPSTHQSMSDAAKTSTAGNASTVIA
HHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCCHHHHHH
DMIAATIKSQHN
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA