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The map label for this gene is pgk

Identifier: 145295708

GI number: 145295708

Start: 1819371

End: 1820588

Strand: Reverse

Name: pgk

Synonym: cgR_1635

Alternate gene names: 145295708

Gene position: 1820588-1819371 (Counterclockwise)

Preceding gene: 145295709

Following gene: 145295707

Centisome position: 54.93

GC content: 58.37

Gene sequence:

>1218_bases
ATGGCTGTTAAGACCCTCAAGGACTTGCTCGACGAAGGCGTAGACGGACGCCACGTCATCGTTCGATCTGACTTCAATGT
TCCCCTCAACGATGACCGCGAGATCACCGATAAGGGCCGAATCATTGCCTCCCTACCAACCCTTAAAGCACTGAGCGAAG
GTGGCGCAAAGGTCATCGTCATGGCTCACCTTGGCCGCCCAAAGGGCGAGGTCAACGAGAAGTACTCCCTCGCACCTGTC
GCTGAGGCACTCTCCGATGAGCTTGGCCAGTACGTTGCACTTGCCGCAGACGTTGTTGGCGAAGACGCACACGAGCGCGC
AAACGGCCTGACCGAGGGCGACATCCTGCTCCTGGAGAACGTGCGCTTCGACCCACGCGAAACCTCCAAGGACGAGGCAG
AGCGCACCGCTTTCGCTCAGGAGCTCGCAGCACTTGCAGCAGACAACGGCGCATTCGTCTCTGACGGCTTCGGTGTTGTC
CACCGCGCACAGACCTCCGTCTACGACATCGCAAAGCTGCTGCCACACTACGCTGGCGGACTGGTTGAGACCGAGATTTC
CGTTCTGGAGAAGATCGCAGAATCACCAGAGGCGCCATACGTAGTGGTTCTCGGTGGATCCAAGGTCTCTGACAAGATCG
GTGTCATCGAGGCACTGGCTGCCAAGGCTGACAAGATCATCGTCGGTGGCGGCATGTGCTACACCTTCCTCGCGGCTCAG
GGACACAACGTTCAGCAGTCCCTCCTGCAGGAAGAAATGAAGGAAACCTGCACCGACCTGCTCGCACGTTTCGGTGACAA
GATCGTCCTCCCAGTTGACCTGGTTGCGGCATCCGAGTTCAACAAGGACGCAGAGAAGCAGATCGTTGACCTGGATTCCA
TCCCAGAAGGCTGGATGTCTCTTGATATCGGACCAGAGTCCGTCAAGAACTTCGGTGAGGTTCTCAGCACCGCTAAGACC
ATCTTCTGGAACGGCCCAATGGGCGTGTTCGAGTTCGCAGCATTCTCTGAGGGCACCCGCGGCATCGCCCAGGCCATCAT
CGATGCAACTGCAGGCAACGACGCATTCTCCGTTGTTGGCGGTGGCGACTCCGCAGCATCTGTTCGCGTGCTCGGCCTGA
ACGAAGACGGCTTCTCCCACATCTCCACCGGTGGTGGCGCATCCCTCGAGTACCTTGAAGGCAAGGAACTCCCAGGCGTT
GCAATTCTCGCTCAGTAA

Upstream 100 bases:

>100_bases
ATACCGGTGCCAGCGCCACACAATGTGTGGCAATCTGGGACAGTGCATCACATTGCACCAGAAGAATTTTTTAAACAATC
AAATCTCCAAGGAGTACGGC

Downstream 100 bases:

>100_bases
ATCCGACACGGCCCTTTTTTAGACAACACAACAAAAGGGCCACCGGGAAACTTTTTAGAAAGGTGTGTTTCACCCATGGC
ACGTAAGCCACTTATCGCTG

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MAVKTLKDLLDEGVDGRHVIVRSDFNVPLNDDREITDKGRIIASLPTLKALSEGGAKVIVMAHLGRPKGEVNEKYSLAPV
AEALSDELGQYVALAADVVGEDAHERANGLTEGDILLLENVRFDPRETSKDEAERTAFAQELAALAADNGAFVSDGFGVV
HRAQTSVYDIAKLLPHYAGGLVETEISVLEKIAESPEAPYVVVLGGSKVSDKIGVIEALAAKADKIIVGGGMCYTFLAAQ
GHNVQQSLLQEEMKETCTDLLARFGDKIVLPVDLVAASEFNKDAEKQIVDLDSIPEGWMSLDIGPESVKNFGEVLSTAKT
IFWNGPMGVFEFAAFSEGTRGIAQAIIDATAGNDAFSVVGGGDSAASVRVLGLNEDGFSHISTGGGASLEYLEGKELPGV
AILAQ

Sequences:

>Translated_405_residues
MAVKTLKDLLDEGVDGRHVIVRSDFNVPLNDDREITDKGRIIASLPTLKALSEGGAKVIVMAHLGRPKGEVNEKYSLAPV
AEALSDELGQYVALAADVVGEDAHERANGLTEGDILLLENVRFDPRETSKDEAERTAFAQELAALAADNGAFVSDGFGVV
HRAQTSVYDIAKLLPHYAGGLVETEISVLEKIAESPEAPYVVVLGGSKVSDKIGVIEALAAKADKIIVGGGMCYTFLAAQ
GHNVQQSLLQEEMKETCTDLLARFGDKIVLPVDLVAASEFNKDAEKQIVDLDSIPEGWMSLDIGPESVKNFGEVLSTAKT
IFWNGPMGVFEFAAFSEGTRGIAQAIIDATAGNDAFSVVGGGDSAASVRVLGLNEDGFSHISTGGGASLEYLEGKELPGV
AILAQ
>Mature_404_residues
AVKTLKDLLDEGVDGRHVIVRSDFNVPLNDDREITDKGRIIASLPTLKALSEGGAKVIVMAHLGRPKGEVNEKYSLAPVA
EALSDELGQYVALAADVVGEDAHERANGLTEGDILLLENVRFDPRETSKDEAERTAFAQELAALAADNGAFVSDGFGVVH
RAQTSVYDIAKLLPHYAGGLVETEISVLEKIAESPEAPYVVVLGGSKVSDKIGVIEALAAKADKIIVGGGMCYTFLAAQG
HNVQQSLLQEEMKETCTDLLARFGDKIVLPVDLVAASEFNKDAEKQIVDLDSIPEGWMSLDIGPESVKNFGEVLSTAKTI
FWNGPMGVFEFAAFSEGTRGIAQAIIDATAGNDAFSVVGGGDSAASVRVLGLNEDGFSHISTGGGASLEYLEGKELPGVA
ILAQ

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family

Homologues:

Organism=Homo sapiens, GI4505763, Length=414, Percent_Identity=41.304347826087, Blast_Score=289, Evalue=3e-78,
Organism=Homo sapiens, GI31543397, Length=414, Percent_Identity=41.304347826087, Blast_Score=283, Evalue=2e-76,
Organism=Escherichia coli, GI1789294, Length=408, Percent_Identity=41.9117647058824, Blast_Score=279, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17508823, Length=406, Percent_Identity=41.6256157635468, Blast_Score=283, Evalue=9e-77,
Organism=Saccharomyces cerevisiae, GI6319857, Length=426, Percent_Identity=40.3755868544601, Blast_Score=288, Evalue=8e-79,
Organism=Drosophila melanogaster, GI24581203, Length=419, Percent_Identity=39.618138424821, Blast_Score=258, Evalue=4e-69,
Organism=Drosophila melanogaster, GI17136394, Length=405, Percent_Identity=39.7530864197531, Blast_Score=256, Evalue=1e-68,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): PGK_CORGB (A4QEG1)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138529.1
- ProteinModelPortal:   A4QEG1
- SMR:   A4QEG1
- STRING:   A4QEG1
- GeneID:   4992885
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1635
- eggNOG:   COG0126
- HOGENOM:   HBG453500
- OMA:   NCAIILP
- ProtClustDB:   PRK00073
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00145
- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824
- Gene3D:   G3DSA:3.40.50.1270
- Gene3D:   G3DSA:3.40.50.1260
- PANTHER:   PTHR11406
- PIRSF:   PIRSF000724
- PRINTS:   PR00477

Pfam domain/function: PF00162 PGK; SSF53748 PGK

EC number: =2.7.2.3

Molecular weight: Translated: 42756; Mature: 42624

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: BINDING 40-40 BINDING 122-122 BINDING 162-162 BINDING 212-212 BINDING 331-331

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKTLKDLLDEGVDGRHVIVRSDFNVPLNDDREITDKGRIIASLPTLKALSEGGAKVIV
CCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCEEEE
MAHLGRPKGEVNEKYSLAPVAEALSDELGQYVALAADVVGEDAHERANGLTEGDILLLEN
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEC
VRFDPRETSKDEAERTAFAQELAALAADNGAFVSDGFGVVHRAQTSVYDIAKLLPHYAGG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCC
LVETEISVLEKIAESPEAPYVVVLGGSKVSDKIGVIEALAAKADKIIVGGGMCYTFLAAQ
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHC
GHNVQQSLLQEEMKETCTDLLARFGDKIVLPVDLVAASEFNKDAEKQIVDLDSIPEGWMS
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCHHHHHHCCCCCCCCCEE
LDIGPESVKNFGEVLSTAKTIFWNGPMGVFEFAAFSEGTRGIAQAIIDATAGNDAFSVVG
ECCCHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEE
GGDSAASVRVLGLNEDGFSHISTGGGASLEYLEGKELPGVAILAQ
CCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEC
>Mature Secondary Structure 
AVKTLKDLLDEGVDGRHVIVRSDFNVPLNDDREITDKGRIIASLPTLKALSEGGAKVIV
CHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCEEEE
MAHLGRPKGEVNEKYSLAPVAEALSDELGQYVALAADVVGEDAHERANGLTEGDILLLEN
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEC
VRFDPRETSKDEAERTAFAQELAALAADNGAFVSDGFGVVHRAQTSVYDIAKLLPHYAGG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCC
LVETEISVLEKIAESPEAPYVVVLGGSKVSDKIGVIEALAAKADKIIVGGGMCYTFLAAQ
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHC
GHNVQQSLLQEEMKETCTDLLARFGDKIVLPVDLVAASEFNKDAEKQIVDLDSIPEGWMS
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCHHHHHHCCCCCCCCCEE
LDIGPESVKNFGEVLSTAKTIFWNGPMGVFEFAAFSEGTRGIAQAIIDATAGNDAFSVVG
ECCCHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEE
GGDSAASVRVLGLNEDGFSHISTGGGASLEYLEGKELPGVAILAQ
CCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA