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The map label for this gene is gap [H]

Identifier: 145295709

GI number: 145295709

Start: 1820805

End: 1821809

Strand: Reverse

Name: gap [H]

Synonym: cgR_1636

Alternate gene names: 145295709

Gene position: 1821809-1820805 (Counterclockwise)

Preceding gene: 145295710

Following gene: 145295708

Centisome position: 54.97

GC content: 57.01

Gene sequence:

>1005_bases
ATGACCATTCGTGTTGGTATTAACGGATTTGGCCGTATCGGACGTAACTTCTTCCGCGCAGTTCTGGAGCGCAGCGACGA
TCTCGAGGTAGTTGCAGTCAACGACCTCACCGACAACAAGACCCTTTCCACCCTTCTCAAGTTCGACTCCATCATGGGCC
GCCTTGGCCAGGAAGTTGAATACGACGATGACTCCATCACCGTTGGTGGCAAGCGCATCGCTGTTTACGCAGAGCGCGAT
CCAAAGAACCTGGACTGGGCTGCACACAACGTTGACATCGTGATCGAGTCCACCGGCTTCTTCACCGATGCAAACGCGGC
TAAGGCTCACATCGAAGCAGGTGCCAAGAAGGTCATCATCTCCGCACCAGCAAGCAACGAAGACGCAACCTTCGTTTACG
GTGTGAACCACGAGTCCTACGATCCTGAGAACCACAACGTGATCTCCGGCGCATCTTGCACCACCAACTGCCTCGCACCA
ATGGCAAAGGTCCTGAACGACAAGTTCGGCATCGAGAACGGCCTCATGACCACCGTTCACGCATACACCGGCGACCAGCG
CCTGCACGATGCACCTCACGGCGACCTGCGTCGTGCACGTGCAGCAGCAGTCAACATCGTTCCTACCTCCACCGGTGCAG
CTAAGGCTGTTGCTCTGGTTCTCCCAGAGCTCAAGGGCAAGCTTGACGGCTACGCACTTCGCGTTCCAGTTATCACCGGT
TCCGCAACCGACCTGACCTTCAACACCAAGTCTGAGGTCACCGTTGAGTCCATCAACGCTGCAATCAAGGAAGCTGCAGT
CGGCGAGTTCGGCGAGACCCTGGCTTACTCCGAAGAGCCACTGGTTTCCACCGACATCGTCCACGATTCCCACGGCTCCA
TCTTCGACGCTGGCCTGACCAAGGTCTCCGGCAACACCGTCAAGGTTGTTTCCTGGTACGACAACGAGTGGGGCTACACC
TGCCAGCTCCTGCGTCTGACCGAGCTCGTAGCTTCCAAGCTCTAA

Upstream 100 bases:

>100_bases
TTGGGTTCTGTCAGCTCAAGAATTCTTGAGTGACCGATGCTCTGATTGACCTAACTGCTTGACACATTGCATTTCCTACA
ATCTTTAGAGGAGACACAAC

Downstream 100 bases:

>100_bases
TTAGTTCACATCGCTAACGTGGGCGATCGATGCTCACGGTGATGTGTCATCCCAATAGCCCGGGGTGTGCCTCGGCGCAC
CCCGGGCTATTTTGTGTCTT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTIRVGINGFGRIGRNFFRAVLERSDDLEVVAVNDLTDNKTLSTLLKFDSIMGRLGQEVEYDDDSITVGGKRIAVYAERD
PKNLDWAAHNVDIVIESTGFFTDANAAKAHIEAGAKKVIISAPASNEDATFVYGVNHESYDPENHNVISGASCTTNCLAP
MAKVLNDKFGIENGLMTTVHAYTGDQRLHDAPHGDLRRARAAAVNIVPTSTGAAKAVALVLPELKGKLDGYALRVPVITG
SATDLTFNTKSEVTVESINAAIKEAAVGEFGETLAYSEEPLVSTDIVHDSHGSIFDAGLTKVSGNTVKVVSWYDNEWGYT
CQLLRLTELVASKL

Sequences:

>Translated_334_residues
MTIRVGINGFGRIGRNFFRAVLERSDDLEVVAVNDLTDNKTLSTLLKFDSIMGRLGQEVEYDDDSITVGGKRIAVYAERD
PKNLDWAAHNVDIVIESTGFFTDANAAKAHIEAGAKKVIISAPASNEDATFVYGVNHESYDPENHNVISGASCTTNCLAP
MAKVLNDKFGIENGLMTTVHAYTGDQRLHDAPHGDLRRARAAAVNIVPTSTGAAKAVALVLPELKGKLDGYALRVPVITG
SATDLTFNTKSEVTVESINAAIKEAAVGEFGETLAYSEEPLVSTDIVHDSHGSIFDAGLTKVSGNTVKVVSWYDNEWGYT
CQLLRLTELVASKL
>Mature_333_residues
TIRVGINGFGRIGRNFFRAVLERSDDLEVVAVNDLTDNKTLSTLLKFDSIMGRLGQEVEYDDDSITVGGKRIAVYAERDP
KNLDWAAHNVDIVIESTGFFTDANAAKAHIEAGAKKVIISAPASNEDATFVYGVNHESYDPENHNVISGASCTTNCLAPM
AKVLNDKFGIENGLMTTVHAYTGDQRLHDAPHGDLRRARAAAVNIVPTSTGAAKAVALVLPELKGKLDGYALRVPVITGS
ATDLTFNTKSEVTVESINAAIKEAAVGEFGETLAYSEEPLVSTDIVHDSHGSIFDAGLTKVSGNTVKVVSWYDNEWGYTC
QLLRLTELVASKL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=334, Percent_Identity=46.7065868263473, Blast_Score=290, Evalue=1e-78,
Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=45.2095808383234, Blast_Score=281, Evalue=4e-76,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=51.8292682926829, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI1789295, Length=336, Percent_Identity=43.452380952381, Blast_Score=281, Evalue=6e-77,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=49.8516320474777, Blast_Score=303, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=50.4451038575668, Blast_Score=302, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=49.8516320474777, Blast_Score=302, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=50.4451038575668, Blast_Score=302, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6322409, Length=332, Percent_Identity=50.9036144578313, Blast_Score=328, Evalue=6e-91,
Organism=Saccharomyces cerevisiae, GI6321631, Length=332, Percent_Identity=52.4096385542169, Blast_Score=328, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6322468, Length=332, Percent_Identity=51.5060240963855, Blast_Score=323, Evalue=2e-89,
Organism=Drosophila melanogaster, GI17933600, Length=334, Percent_Identity=47.6047904191617, Blast_Score=292, Evalue=2e-79,
Organism=Drosophila melanogaster, GI18110149, Length=334, Percent_Identity=47.6047904191617, Blast_Score=292, Evalue=2e-79,
Organism=Drosophila melanogaster, GI85725000, Length=334, Percent_Identity=47.6047904191617, Blast_Score=291, Evalue=3e-79,
Organism=Drosophila melanogaster, GI22023983, Length=334, Percent_Identity=47.6047904191617, Blast_Score=291, Evalue=3e-79,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=47.0769230769231, Blast_Score=283, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35947; Mature: 35815

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRVGINGFGRIGRNFFRAVLERSDDLEVVAVNDLTDNKTLSTLLKFDSIMGRLGQEVE
CEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
YDDDSITVGGKRIAVYAERDPKNLDWAAHNVDIVIESTGFFTDANAAKAHIEAGAKKVII
CCCCEEEECCEEEEEEECCCCCCCCEEECCEEEEEECCCCEECCCHHHHHHHCCCEEEEE
SAPASNEDATFVYGVNHESYDPENHNVISGASCTTNCLAPMAKVLNDKFGIENGLMTTVH
ECCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
AYTGDQRLHDAPHGDLRRARAAAVNIVPTSTGAAKAVALVLPELKGKLDGYALRVPVITG
EECCCCCCCCCCCHHHHHHHHHEEEEEECCCCHHHHHHEEEHHHCCCCCCEEEEEEEEEC
SATDLTFNTKSEVTVESINAAIKEAAVGEFGETLAYSEEPLVSTDIVHDSHGSIFDAGLT
CCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCCE
KVSGNTVKVVSWYDNEWGYTCQLLRLTELVASKL
EECCCEEEEEEEECCCCCCEEHHHHHHHHHHHCC
>Mature Secondary Structure 
TIRVGINGFGRIGRNFFRAVLERSDDLEVVAVNDLTDNKTLSTLLKFDSIMGRLGQEVE
EEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
YDDDSITVGGKRIAVYAERDPKNLDWAAHNVDIVIESTGFFTDANAAKAHIEAGAKKVII
CCCCEEEECCEEEEEEECCCCCCCCEEECCEEEEEECCCCEECCCHHHHHHHCCCEEEEE
SAPASNEDATFVYGVNHESYDPENHNVISGASCTTNCLAPMAKVLNDKFGIENGLMTTVH
ECCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
AYTGDQRLHDAPHGDLRRARAAAVNIVPTSTGAAKAVALVLPELKGKLDGYALRVPVITG
EECCCCCCCCCCCHHHHHHHHHEEEEEECCCCHHHHHHEEEHHHCCCCCCEEEEEEEEEC
SATDLTFNTKSEVTVESINAAIKEAAVGEFGETLAYSEEPLVSTDIVHDSHGSIFDAGLT
CCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCCE
KVSGNTVKVVSWYDNEWGYTCQLLRLTELVASKL
EECCCEEEEEEEECCCCCCEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400158; 12948626 [H]