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The map label for this gene is mtrA [H]

Identifier: 145294917

GI number: 145294917

Start: 950981

End: 951661

Strand: Direct

Name: mtrA [H]

Synonym: cgR_0863

Alternate gene names: 145294917

Gene position: 950981-951661 (Clockwise)

Preceding gene: 145294916

Following gene: 145294918

Centisome position: 28.69

GC content: 56.24

Gene sequence:

>681_bases
ATGTCACAGAAAATTCTCGTCGTTGATGATGATCCCGCCATCTCCGAGATGCTCACCATCGTGCTCAGCGCAGAAGGCTT
TGACACCGTAGCTGTCACCGACGGCGCACTCGCCGTGGAAACCGCCTCCCGGGAACAACCGGATCTGATTTTGCTCGACT
TGATGCTTCCAGGCATGAACGGCATCGACATTTGTCGCCTCATCCGCCAAGAATCCTCCGTACCCATCATCATGCTCACC
GCCAAAACCGACACCGTTGATGTGGTGCTCGGTTTGGAATCCGGTGCAGACGATTACGTGAACAAGCCTTTCAAAGCGAA
AGAACTTGTCGCCCGCATCCGTGCCCGCCTCCGCGCAACCGTGGACGAGCCCAGCGAAATCCTCGAAGTCGGCGATCTGT
CCATCGACGTCCCAGCACACACCGTCAAACGAAACGGCGCTGAGATTTCCTTGACCCCGCTCGAATTCGACCTCCTGCTG
GAACTCGCCCGCAAACCACAGCAAGTATTCACCCGTGAGGAATTGCTGGGCAAAGTGTGGGGCTACCGCCATGCATCCGA
CACTCGACTGGTCAACGTTCACGTTCAGCGTCTGCGCGCCAAGATTGAAAAAGATCCAGAAAATCCGCAGATCGTCCTCA
CCGTCCGCGGTGTTGGCTACAAAACTGGCCACAGCGATTAA

Upstream 100 bases:

>100_bases
GATCGTGGTTGCCCCTGATGAAGACCCCGGCCACGTTGCGCAGAGAATCGTGGAATTCCTGGGTACTATAAACTAATCCC
AATTAGCAGGAAGGATTCTC

Downstream 100 bases:

>100_bases
GTTTTTCATTTAAAAAAGGGGCAGTTTCTCATTCTTGCCTGGCTCACGCGACTTCGACATCGCATTGTAGATAAATGGCG
AACCTCACTGCAGGTTCGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSQKILVVDDDPAISEMLTIVLSAEGFDTVAVTDGALAVETASREQPDLILLDLMLPGMNGIDICRLIRQESSVPIIMLT
AKTDTVDVVLGLESGADDYVNKPFKAKELVARIRARLRATVDEPSEILEVGDLSIDVPAHTVKRNGAEISLTPLEFDLLL
ELARKPQQVFTREELLGKVWGYRHASDTRLVNVHVQRLRAKIEKDPENPQIVLTVRGVGYKTGHSD

Sequences:

>Translated_226_residues
MSQKILVVDDDPAISEMLTIVLSAEGFDTVAVTDGALAVETASREQPDLILLDLMLPGMNGIDICRLIRQESSVPIIMLT
AKTDTVDVVLGLESGADDYVNKPFKAKELVARIRARLRATVDEPSEILEVGDLSIDVPAHTVKRNGAEISLTPLEFDLLL
ELARKPQQVFTREELLGKVWGYRHASDTRLVNVHVQRLRAKIEKDPENPQIVLTVRGVGYKTGHSD
>Mature_225_residues
SQKILVVDDDPAISEMLTIVLSAEGFDTVAVTDGALAVETASREQPDLILLDLMLPGMNGIDICRLIRQESSVPIIMLTA
KTDTVDVVLGLESGADDYVNKPFKAKELVARIRARLRATVDEPSEILEVGDLSIDVPAHTVKRNGAEISLTPLEFDLLLE
LARKPQQVFTREELLGKVWGYRHASDTRLVNVHVQRLRAKIEKDPENPQIVLTVRGVGYKTGHSD

Specific function: Member of the two-component regulatory system mtrA/mtrB [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=42.2222222222222, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=38.3259911894273, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI87082012, Length=217, Percent_Identity=40.0921658986175, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=39.0134529147982, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=37.219730941704, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=41.8181818181818, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.9366515837104, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=32.3008849557522, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=40.2654867256637, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=33.3333333333333, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=35.3211009174312, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=34.3891402714932, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=33.7719298245614, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=29.6803652968037, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=35.1851851851852, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=35.1851851851852, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787487, Length=150, Percent_Identity=27.3333333333333, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24916; Mature: 24785

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKILVVDDDPAISEMLTIVLSAEGFDTVAVTDGALAVETASREQPDLILLDLMLPGMN
CCCEEEEEECCHHHHHHHHHHEECCCCCEEEEECCEEEEEECCCCCCCEEEEEEECCCCC
GIDICRLIRQESSVPIIMLTAKTDTVDVVLGLESGADDYVNKPFKAKELVARIRARLRAT
HHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHCC
VDEPSEILEVGDLSIDVPAHTVKRNGAEISLTPLEFDLLLELARKPQQVFTREELLGKVW
CCCHHHHHHHCCCEEECCHHHHHCCCCEEEEECCHHHHHHHHHHCHHHHHHHHHHHHHHH
GYRHASDTRLVNVHVQRLRAKIEKDPENPQIVLTVRGVGYKTGHSD
CCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SQKILVVDDDPAISEMLTIVLSAEGFDTVAVTDGALAVETASREQPDLILLDLMLPGMN
CCEEEEEECCHHHHHHHHHHEECCCCCEEEEECCEEEEEECCCCCCCEEEEEEECCCCC
GIDICRLIRQESSVPIIMLTAKTDTVDVVLGLESGADDYVNKPFKAKELVARIRARLRAT
HHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHCC
VDEPSEILEVGDLSIDVPAHTVKRNGAEISLTPLEFDLLLELARKPQQVFTREELLGKVW
CCCHHHHHHHCCCEEECCHHHHHCCCCEEEEECCHHHHHHHHHHCHHHHHHHHHHHHHHH
GYRHASDTRLVNVHVQRLRAKIEKDPENPQIVLTVRGVGYKTGHSD
CCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]