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The map label for this gene is mtrB [H]

Identifier: 145294918

GI number: 145294918

Start: 951761

End: 953260

Strand: Direct

Name: mtrB [H]

Synonym: cgR_0864

Alternate gene names: 145294918

Gene position: 951761-953260 (Clockwise)

Preceding gene: 145294917

Following gene: 145294919

Centisome position: 28.72

GC content: 56.87

Gene sequence:

>1500_bases
GTGCTCGGCTCCATCTTCACCGCATCAGCTGTCGTGATGATCCTTTTGGGGCTGGGCATGCTGACTGTATTCACCCAACG
GTTGGTGGATCAGAAAATCGATATTGCGAGCTCCGAAATCGACCGCGCCCGCGTCATCGTCGAAGAACAAATCACCGCAT
CCGGCGCCTCAACATCGGTGCAGGCCCGAGTGAACTCTGCCCGCGCTGCGCTCTCCAGCTTGGGTACCAGCGGCGGTACA
GAAACCAACGCCGCCTACGATCCAGTCGTGTTGGTGAACAACGATGACCTGGTGGTCTCTCCCGAGGGTTACCAAATCCC
AGAACGTCTGCGATACTTCGTCTCTGAGAACCAAGTCTCGTATCAGTTCTCCAGCATCGACCAAGGCGACGGATCGTCCT
ACCAAGCGCTCATCATCGGAACGCCCACGGAAAGCGACATCCCGAACCTCCAGGTGTATCTGGTGTTCTCCATGGAAAGC
GACGAATCCTCTCTTGCTCTCATGCGAGGACTCCTCTCAGCTGCACTGCTGATCGTGGTGGTGCTGCTGGTCGGTATCGC
ATGGCTTGCCACCCAACAGGTCACCGCGCCGGTGCGTTCGGCGAGCCGGATTGCGGAGCGTTTCGCTCAAGGCAAACTGC
GTGAACGCATGGTGGTGGAAGGCGAAGACGAGATGGCCCGCCTGGCGGTGTCCTTCAACGCGATGGCCGAATCGCTGTCC
GCGCAGATCACCAAATTGGAGGAATACGGCAATCTGCAACGACAATTCACATCGGATGTCTCACACGAATTGCGCACACC
GCTGACAACGGTGCGCATGGCTGCTGATCTAATTGCCGATAGTGAAGATGAACTTTCACCCGGTGCGCGCCGCGCCAGCC
AACTGATGAACAGGGAGTTGGACCGATTCGAGTCGCTGCTGAGCGATCTGTTGGAAATTTCCCGACACGACGCCGGCGTT
GCCGAACTGTCCACCGCGCTTCACGATGTCCGCATCCCAGTGCGATCGGCATTGGAACAAGTACAACACTTGGCCACCGA
GCTCGATGTGGAATTGCTTGTTGATTTGCCCGAAGAAGCGATCAACATTCAAGGCGATTCCAGGCGCATCGAAAGAATCA
TTCGCAACCTTCTAGCCAATGCGATCGACCACTCCAGGGGCTTGCCGGTTGAGTTGAAAGTTGCCGACAACGAGGACGCA
GTAGCGATCGTTGTTATTGATCACGGCGTCGGCCTGAAACCTGGACAAGACGAATTGGTGTTCAACAGATTCTGGCGAGC
CGACCCTTCGCGCGTCCGCCATTCTGGTGGCACCGGCCTGGGTCTTGCGATTTCTCGCGAAGATGCGATGCTTCATGGAG
GAAACCTTGATGCGGCGGGAACGATCGGTGTTGGTTCCATTTTCCGTTTGGTCTTGCCTAAAGAGCCGCATGGAAATTAT
CGTGAAGCACCGATCCCGTTGATCGCTCCAGAGACACCGTGGGAAGGGGAGCAGCAGTGA

Upstream 100 bases:

>100_bases
AGTTTTTCATTTAAAAAAGGGGCAGTTTCTCATTCTTGCCTGGCTCACGCGACTTCGACATCGCATTGTAGATAAATGGC
GAACCTCACTGCAGGTTCGC

Downstream 100 bases:

>100_bases
GTAAAATTTCGACGAAACTGAAGGCCCTCTCCGCGGTGCTGTCTGTGACAACTCTGGTGGCTGGGTGTTCCACGCTTCCG
CAGAACACGGATCCGCAAGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MLGSIFTASAVVMILLGLGMLTVFTQRLVDQKIDIASSEIDRARVIVEEQITASGASTSVQARVNSARAALSSLGTSGGT
ETNAAYDPVVLVNNDDLVVSPEGYQIPERLRYFVSENQVSYQFSSIDQGDGSSYQALIIGTPTESDIPNLQVYLVFSMES
DESSLALMRGLLSAALLIVVVLLVGIAWLATQQVTAPVRSASRIAERFAQGKLRERMVVEGEDEMARLAVSFNAMAESLS
AQITKLEEYGNLQRQFTSDVSHELRTPLTTVRMAADLIADSEDELSPGARRASQLMNRELDRFESLLSDLLEISRHDAGV
AELSTALHDVRIPVRSALEQVQHLATELDVELLVDLPEEAINIQGDSRRIERIIRNLLANAIDHSRGLPVELKVADNEDA
VAIVVIDHGVGLKPGQDELVFNRFWRADPSRVRHSGGTGLGLAISREDAMLHGGNLDAAGTIGVGSIFRLVLPKEPHGNY
REAPIPLIAPETPWEGEQQ

Sequences:

>Translated_499_residues
MLGSIFTASAVVMILLGLGMLTVFTQRLVDQKIDIASSEIDRARVIVEEQITASGASTSVQARVNSARAALSSLGTSGGT
ETNAAYDPVVLVNNDDLVVSPEGYQIPERLRYFVSENQVSYQFSSIDQGDGSSYQALIIGTPTESDIPNLQVYLVFSMES
DESSLALMRGLLSAALLIVVVLLVGIAWLATQQVTAPVRSASRIAERFAQGKLRERMVVEGEDEMARLAVSFNAMAESLS
AQITKLEEYGNLQRQFTSDVSHELRTPLTTVRMAADLIADSEDELSPGARRASQLMNRELDRFESLLSDLLEISRHDAGV
AELSTALHDVRIPVRSALEQVQHLATELDVELLVDLPEEAINIQGDSRRIERIIRNLLANAIDHSRGLPVELKVADNEDA
VAIVVIDHGVGLKPGQDELVFNRFWRADPSRVRHSGGTGLGLAISREDAMLHGGNLDAAGTIGVGSIFRLVLPKEPHGNY
REAPIPLIAPETPWEGEQQ
>Mature_499_residues
MLGSIFTASAVVMILLGLGMLTVFTQRLVDQKIDIASSEIDRARVIVEEQITASGASTSVQARVNSARAALSSLGTSGGT
ETNAAYDPVVLVNNDDLVVSPEGYQIPERLRYFVSENQVSYQFSSIDQGDGSSYQALIIGTPTESDIPNLQVYLVFSMES
DESSLALMRGLLSAALLIVVVLLVGIAWLATQQVTAPVRSASRIAERFAQGKLRERMVVEGEDEMARLAVSFNAMAESLS
AQITKLEEYGNLQRQFTSDVSHELRTPLTTVRMAADLIADSEDELSPGARRASQLMNRELDRFESLLSDLLEISRHDAGV
AELSTALHDVRIPVRSALEQVQHLATELDVELLVDLPEEAINIQGDSRRIERIIRNLLANAIDHSRGLPVELKVADNEDA
VAIVVIDHGVGLKPGQDELVFNRFWRADPSRVRHSGGTGLGLAISREDAMLHGGNLDAAGTIGVGSIFRLVLPKEPHGNY
REAPIPLIAPETPWEGEQQ

Specific function: Member of the two-component regulatory system mtrA/mtrB. Seems to function as a membrane-associated protein kinase that phosphorylates mtrA in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=312, Percent_Identity=29.8076923076923, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1787894, Length=274, Percent_Identity=31.021897810219, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788393, Length=281, Percent_Identity=29.1814946619217, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1786783, Length=333, Percent_Identity=26.7267267267267, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789149, Length=342, Percent_Identity=26.9005847953216, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=28.5106382978723, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786912, Length=264, Percent_Identity=30.3030303030303, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081816, Length=361, Percent_Identity=29.6398891966759, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=28, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=28.2051282051282, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790551, Length=290, Percent_Identity=28.2758620689655, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=27.8688524590164, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788279, Length=252, Percent_Identity=26.1904761904762, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789808, Length=297, Percent_Identity=25.5892255892256, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789403, Length=231, Percent_Identity=31.1688311688312, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=229, Percent_Identity=27.9475982532751, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87082128, Length=313, Percent_Identity=23.6421725239617, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54249; Mature: 54249

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGSIFTASAVVMILLGLGMLTVFTQRLVDQKIDIASSEIDRARVIVEEQITASGASTSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
QARVNSARAALSSLGTSGGTETNAAYDPVVLVNNDDLVVSPEGYQIPERLRYFVSENQVS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEECCCCCCCHHHHHHHHCCCCEE
YQFSSIDQGDGSSYQALIIGTPTESDIPNLQVYLVFSMESDESSLALMRGLLSAALLIVV
EEECCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VLLVGIAWLATQQVTAPVRSASRIAERFAQGKLRERMVVEGEDEMARLAVSFNAMAESLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHH
AQITKLEEYGNLQRQFTSDVSHELRTPLTTVRMAADLIADSEDELSPGARRASQLMNREL
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
DRFESLLSDLLEISRHDAGVAELSTALHDVRIPVRSALEQVQHLATELDVELLVDLPEEA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHEEECCHHH
INIQGDSRRIERIIRNLLANAIDHSRGLPVELKVADNEDAVAIVVIDHGVGLKPGQDELV
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCHHHH
FNRFWRADPSRVRHSGGTGLGLAISREDAMLHGGNLDAAGTIGVGSIFRLVLPKEPHGNY
HHHHHCCCHHHHHCCCCCCEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCCC
REAPIPLIAPETPWEGEQQ
CCCCCCEECCCCCCCCCCC
>Mature Secondary Structure
MLGSIFTASAVVMILLGLGMLTVFTQRLVDQKIDIASSEIDRARVIVEEQITASGASTSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
QARVNSARAALSSLGTSGGTETNAAYDPVVLVNNDDLVVSPEGYQIPERLRYFVSENQVS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEECCCCCCCHHHHHHHHCCCCEE
YQFSSIDQGDGSSYQALIIGTPTESDIPNLQVYLVFSMESDESSLALMRGLLSAALLIVV
EEECCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VLLVGIAWLATQQVTAPVRSASRIAERFAQGKLRERMVVEGEDEMARLAVSFNAMAESLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHH
AQITKLEEYGNLQRQFTSDVSHELRTPLTTVRMAADLIADSEDELSPGARRASQLMNREL
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
DRFESLLSDLLEISRHDAGVAELSTALHDVRIPVRSALEQVQHLATELDVELLVDLPEEA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHEEECCHHH
INIQGDSRRIERIIRNLLANAIDHSRGLPVELKVADNEDAVAIVVIDHGVGLKPGQDELV
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCHHHH
FNRFWRADPSRVRHSGGTGLGLAISREDAMLHGGNLDAAGTIGVGSIFRLVLPKEPHGNY
HHHHHCCCHHHHHCCCCCCEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCCC
REAPIPLIAPETPWEGEQQ
CCCCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]