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The map label for this gene is yycF [H]

Identifier: 138897044

GI number: 138897044

Start: 3522441

End: 3523154

Strand: Reverse

Name: yycF [H]

Synonym: GTNG_3415

Alternate gene names: 138897044

Gene position: 3523154-3522441 (Counterclockwise)

Preceding gene: 138897045

Following gene: 138897043

Centisome position: 99.23

GC content: 47.34

Gene sequence:

>714_bases
ATGGAAAAACGCATTTTAGTTGTTGATGATGAAAAACCGATTGCTGATATTTTGCAATTTAACTTACAAAAAGAAGGATA
CGAAGTGATTTGCGCTTACGACGGTGAAGAAGCGCTTCAAAAAGTAGAAGAAACAATGCCGGATTTAATTTTGCTTGATA
TTATGCTTCCGCTAAAAGATGGGATGGAAGTATGCCGCGAAGTGCGAAAAAAATACGATATGCCAATTATTATGCTGACG
GCGAAAGACTCGGAGATTGATAAAGTGCTTGGACTGGAGCTCGGAGCAGACGATTATGTCACCAAACCGTTCAGCACGCG
GGAGCTATTGGCGCGGGTGAAAGCGAACTTGCGCCGCCATGCGCAAACAGCGACCCAAGAGGAAGAGGAGAGCGAAACGA
ATGAAATCGTCGTCGGTCCGCTTGTAATCCGTCCGGACGCGTATGTCGTACAAAAGCGCGGGGAAACGATTGAATTGACT
CACCGCGAATTTGAACTGCTCCACTATTTGGCGAAACATATTGGCCAAGTGATGACGCGCGAGCATTTGTTGCAAACGGT
CTGGGGTTATGACTATTATGGCGATGTACGCACGGTCGATGTAACGGTAAGACGGCTGCGTGAAAAAATTGAGGATAACC
CTTCTCACCCGTCATGGATCGTTACTAGACGGGGGGTCGGCTACTACTTGCGCAACCCGGAACAGGAGTCATGA

Upstream 100 bases:

>100_bases
CCCCCTCAAAATGGCAATCGACAAAGGATGATTTCATTTTCATAACATGATAAATTAGTAATGATAGCATTCCATCGCAA
AAGGGAAGGATGTGAACGAG

Downstream 100 bases:

>100_bases
GCCGAGATGAAAAAGTTAGGTCCGTTTCGTTCGATTCATTTTAAGTTTGTCATTATTTATGTGTTGTTGATTCTCATTGC
GATGCAATTATTGGGCGTGT

Product: two-component response regulater

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MEKRILVVDDEKPIADILQFNLQKEGYEVICAYDGEEALQKVEETMPDLILLDIMLPLKDGMEVCREVRKKYDMPIIMLT
AKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRRHAQTATQEEEESETNEIVVGPLVIRPDAYVVQKRGETIELT
HREFELLHYLAKHIGQVMTREHLLQTVWGYDYYGDVRTVDVTVRRLREKIEDNPSHPSWIVTRRGVGYYLRNPEQES

Sequences:

>Translated_237_residues
MEKRILVVDDEKPIADILQFNLQKEGYEVICAYDGEEALQKVEETMPDLILLDIMLPLKDGMEVCREVRKKYDMPIIMLT
AKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRRHAQTATQEEEESETNEIVVGPLVIRPDAYVVQKRGETIELT
HREFELLHYLAKHIGQVMTREHLLQTVWGYDYYGDVRTVDVTVRRLREKIEDNPSHPSWIVTRRGVGYYLRNPEQES
>Mature_237_residues
MEKRILVVDDEKPIADILQFNLQKEGYEVICAYDGEEALQKVEETMPDLILLDIMLPLKDGMEVCREVRKKYDMPIIMLT
AKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRRHAQTATQEEEESETNEIVVGPLVIRPDAYVVQKRGETIELT
HREFELLHYLAKHIGQVMTREHLLQTVWGYDYYGDVRTVDVTVRRLREKIEDNPSHPSWIVTRRGVGYYLRNPEQES

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=42.9824561403509, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=41.991341991342, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=42.2907488986784, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=37.1681415929204, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1786784, Length=234, Percent_Identity=40.1709401709402, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=37.6106194690265, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1790863, Length=225, Percent_Identity=36, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=38.5281385281385, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=37.3913043478261, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=35.2173913043478, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=35.4978354978355, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=35.042735042735, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=32.4561403508772, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=33.1877729257642, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=37.962962962963, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790299, Length=137, Percent_Identity=28.4671532846715, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=35.9649122807018, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27559; Mature: 27559

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRILVVDDEKPIADILQFNLQKEGYEVICAYDGEEALQKVEETMPDLILLDIMLPLKD
CCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHH
GMEVCREVRKKYDMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRRH
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHHH
AQTATQEEEESETNEIVVGPLVIRPDAYVVQKRGETIELTHREFELLHYLAKHIGQVMTR
HHHHHHHHHHCCCCCEEEEEEEECCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHH
EHLLQTVWGYDYYGDVRTVDVTVRRLREKIEDNPSHPSWIVTRRGVGYYLRNPEQES
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCCCCC
>Mature Secondary Structure
MEKRILVVDDEKPIADILQFNLQKEGYEVICAYDGEEALQKVEETMPDLILLDIMLPLKD
CCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHH
GMEVCREVRKKYDMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELLARVKANLRRH
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHHH
AQTATQEEEESETNEIVVGPLVIRPDAYVVQKRGETIELTHREFELLHYLAKHIGQVMTR
HHHHHHHHHHCCCCCEEEEEEEECCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHH
EHLLQTVWGYDYYGDVRTVDVTVRRLREKIEDNPSHPSWIVTRRGVGYYLRNPEQES
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]