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The map label for this gene is yycG [H]

Identifier: 138897043

GI number: 138897043

Start: 3520605

End: 3522434

Strand: Reverse

Name: yycG [H]

Synonym: GTNG_3414

Alternate gene names: 138897043

Gene position: 3522434-3520605 (Counterclockwise)

Preceding gene: 138897044

Following gene: 138897042

Centisome position: 99.21

GC content: 47.65

Gene sequence:

>1830_bases
ATGAAAAAGTTAGGTCCGTTTCGTTCGATTCATTTTAAGTTTGTCATTATTTATGTGTTGTTGATTCTCATTGCGATGCA
ATTATTGGGCGTGTACTTCGTCCGCAAGCTGGAAACGGAACTGGTGCAAAACTTCAAAAACTCGTTGAACGAACGGGTGA
CGCTGCTTGCTTATAACGTTGAGCAGGCAATGAGTCGGGAGCGGGATGAGAAAAGCCCGACATTGGAGGAAGACATCCGT
TCGCTTCTTCATGATTTCGTTTCCCAAGATATTTCAGAGGTGCGCGTCATCGATGAGAAAGGGAAAGTATTGGCGACGTC
CAATCCGTATATGCAAAACATCGTCGGAAAGCGAACGACGGAGATTTATGTGAAACGTTCGCTCGTCACGGGTGAAATTG
TCGACCGGATGCTGCTTGATTCGAAGACAGGCTATCGGATGTACATTTCCTCAACTCCGATCAAAACGAGTGGGGAAGTC
AAGGGTGTCATTTATGTGATTGCCTCGATGGAAAACGTCTTTTCACAAATGAGGCAAATTAATATGATTTTGGCGACCGG
AACGGGGATCGCTCTCGCCATTACCGCCGTGCTCGGCATTTTTTTGTCGCGCACGATCACCCGCCCCATTTCCGATATGC
GCCGACAAGCGCTGGCGATGACGAGAGGCGATTTTTCACGCAAGGTGAAAGTGTATGGCTACGATGAAATCGGGCAGCTG
GCGATGACGTTTAACAACTTGACAAAAAAGCTGCAGGAGGCGCAGGCAACGACGGAAGGGGAGCGGCGCAAACTTGAGTC
GGTGCTGACACATATGACCGACGGGGTCATCGCGACCGACCGCCGCGGCCGCGTCATTTTGATTAATGATGCAGCGCTCA
ACATTTTGAATGTTTCACGTGAAACAGTGCTGTCGAGTTCAATTGTTGATGTGCTTGGCATCGCCGATCAATATACGTTT
GAAACGTTGCTCGAGGAGCACGATTCGCTCATTTTGGATTTCAGCACAGATGAGGAATTGTATATTTTGCGCGCCTCGTT
GTCAGTCATTCAAAAAGAAGGCGGACTGATCAACGGGTTGATCGTCGTCTTGCACGACGTGACTGAACAGGAAAAAATCG
ACCGCGAACGGCGGCAGTTTGTCGCCAATGTGTCGCATGAATTGCGCACGCCGCTGACGACGATGAAAAGTTATTTAGAA
GCGTTGGCTGACGGTGCTTGGCAAGATAAAGAGATCACACCAAGATTCATTCAAGTCGTGCAAAATGAAACCGAGCGGAT
GATTCGGCTCGTCAACGATTTGCTCCATCTATCGAAACTAGACAGCAAAGACTATAAACTGAAGAAAACGTGGATCAACT
TCTCGGCTTATTTTCACAAAATTATTGACCGGTTTGAACTGACGAAAAGCGACAATATCCGGTTTGTTCGCAACATTCCA
CGCGAGGCGATTTTCATTGAAGTGGATGAAGATAAAATTACGCAAGTGTTGGATAACATCATTTCCAACGCAATAAAATA
CTCTCCCCAAGGTGGGACGATCACGTTTCGGGTGCGCGAGCTGGCTGATGAAATCATCATTAGTATCAGCGATGAAGGAG
TCGGCATTCCGAAAGCGGATTTGGCCAAAATTTTTGAGCGTTTTTACCGGGTCGATAAGGCACGGTCGCGCAAATTGGGT
GGCACCGGCCTTGGACTGGCCATTGCCAAAGAATTGGTGATCGCCCACGGTGGGACAATTTGGGCGGAAAGCAAAGAACA
TAAAGGGACGACGATTTACTTTACGTTGCCATTAGAACGAGAACAAAAGGATGACTGGTACAATGTATGA

Upstream 100 bases:

>100_bases
TGAAAAAATTGAGGATAACCCTTCTCACCCGTCATGGATCGTTACTAGACGGGGGGTCGGCTACTACTTGCGCAACCCGG
AACAGGAGTCATGAGCCGAG

Downstream 100 bases:

>100_bases
GCAGATTAAAACAGTCGTGTTGACGGTGCTCGTGCTGATCAGCATTACGTTGACGTTTGTTTTATGGACATACTATCCGA
AATATGATGTGCTGCAAAAC

Product: sensory box histidine kinase YycG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MKKLGPFRSIHFKFVIIYVLLILIAMQLLGVYFVRKLETELVQNFKNSLNERVTLLAYNVEQAMSRERDEKSPTLEEDIR
SLLHDFVSQDISEVRVIDEKGKVLATSNPYMQNIVGKRTTEIYVKRSLVTGEIVDRMLLDSKTGYRMYISSTPIKTSGEV
KGVIYVIASMENVFSQMRQINMILATGTGIALAITAVLGIFLSRTITRPISDMRRQALAMTRGDFSRKVKVYGYDEIGQL
AMTFNNLTKKLQEAQATTEGERRKLESVLTHMTDGVIATDRRGRVILINDAALNILNVSRETVLSSSIVDVLGIADQYTF
ETLLEEHDSLILDFSTDEELYILRASLSVIQKEGGLINGLIVVLHDVTEQEKIDRERRQFVANVSHELRTPLTTMKSYLE
ALADGAWQDKEITPRFIQVVQNETERMIRLVNDLLHLSKLDSKDYKLKKTWINFSAYFHKIIDRFELTKSDNIRFVRNIP
REAIFIEVDEDKITQVLDNIISNAIKYSPQGGTITFRVRELADEIIISISDEGVGIPKADLAKIFERFYRVDKARSRKLG
GTGLGLAIAKELVIAHGGTIWAESKEHKGTTIYFTLPLEREQKDDWYNV

Sequences:

>Translated_609_residues
MKKLGPFRSIHFKFVIIYVLLILIAMQLLGVYFVRKLETELVQNFKNSLNERVTLLAYNVEQAMSRERDEKSPTLEEDIR
SLLHDFVSQDISEVRVIDEKGKVLATSNPYMQNIVGKRTTEIYVKRSLVTGEIVDRMLLDSKTGYRMYISSTPIKTSGEV
KGVIYVIASMENVFSQMRQINMILATGTGIALAITAVLGIFLSRTITRPISDMRRQALAMTRGDFSRKVKVYGYDEIGQL
AMTFNNLTKKLQEAQATTEGERRKLESVLTHMTDGVIATDRRGRVILINDAALNILNVSRETVLSSSIVDVLGIADQYTF
ETLLEEHDSLILDFSTDEELYILRASLSVIQKEGGLINGLIVVLHDVTEQEKIDRERRQFVANVSHELRTPLTTMKSYLE
ALADGAWQDKEITPRFIQVVQNETERMIRLVNDLLHLSKLDSKDYKLKKTWINFSAYFHKIIDRFELTKSDNIRFVRNIP
REAIFIEVDEDKITQVLDNIISNAIKYSPQGGTITFRVRELADEIIISISDEGVGIPKADLAKIFERFYRVDKARSRKLG
GTGLGLAIAKELVIAHGGTIWAESKEHKGTTIYFTLPLEREQKDDWYNV
>Mature_609_residues
MKKLGPFRSIHFKFVIIYVLLILIAMQLLGVYFVRKLETELVQNFKNSLNERVTLLAYNVEQAMSRERDEKSPTLEEDIR
SLLHDFVSQDISEVRVIDEKGKVLATSNPYMQNIVGKRTTEIYVKRSLVTGEIVDRMLLDSKTGYRMYISSTPIKTSGEV
KGVIYVIASMENVFSQMRQINMILATGTGIALAITAVLGIFLSRTITRPISDMRRQALAMTRGDFSRKVKVYGYDEIGQL
AMTFNNLTKKLQEAQATTEGERRKLESVLTHMTDGVIATDRRGRVILINDAALNILNVSRETVLSSSIVDVLGIADQYTF
ETLLEEHDSLILDFSTDEELYILRASLSVIQKEGGLINGLIVVLHDVTEQEKIDRERRQFVANVSHELRTPLTTMKSYLE
ALADGAWQDKEITPRFIQVVQNETERMIRLVNDLLHLSKLDSKDYKLKKTWINFSAYFHKIIDRFELTKSDNIRFVRNIP
REAIFIEVDEDKITQVLDNIISNAIKYSPQGGTITFRVRELADEIIISISDEGVGIPKADLAKIFERFYRVDKARSRKLG
GTGLGLAIAKELVIAHGGTIWAESKEHKGTTIYFTLPLEREQKDDWYNV

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=365, Percent_Identity=29.3150684931507, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=33.1896551724138, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI1786783, Length=236, Percent_Identity=31.3559322033898, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788549, Length=516, Percent_Identity=24.4186046511628, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI48994928, Length=273, Percent_Identity=28.5714285714286, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790346, Length=234, Percent_Identity=31.1965811965812, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=29.3388429752066, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788713, Length=234, Percent_Identity=29.0598290598291, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=30.0429184549356, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=28.2700421940928, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=33.4763948497854, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI87081816, Length=235, Percent_Identity=28.936170212766, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1787894, Length=233, Percent_Identity=24.8927038626609, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1790861, Length=202, Percent_Identity=27.7227722772277, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1790551, Length=255, Percent_Identity=28.2352941176471, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=23.5042735042735, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789403, Length=218, Percent_Identity=29.8165137614679, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790300, Length=235, Percent_Identity=28.0851063829787, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787374, Length=263, Percent_Identity=25.8555133079848, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=211, Percent_Identity=28.9099526066351, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69420; Mature: 69420

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLGPFRSIHFKFVIIYVLLILIAMQLLGVYFVRKLETELVQNFKNSLNERVTLLAYNV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECH
EQAMSRERDEKSPTLEEDIRSLLHDFVSQDISEVRVIDEKGKVLATSNPYMQNIVGKRTT
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHEEECCCCCEEECCCCHHHHHHCCCHH
EIYVKRSLVTGEIVDRMLLDSKTGYRMYISSTPIKTSGEVKGVIYVIASMENVFSQMRQI
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
NMILATGTGIALAITAVLGIFLSRTITRPISDMRRQALAMTRGDFSRKVKVYGYDEIGQL
HEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHH
AMTFNNLTKKLQEAQATTEGERRKLESVLTHMTDGVIATDRRGRVILINDAALNILNVSR
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCHHHHHHCHH
ETVLSSSIVDVLGIADQYTFETLLEEHDSLILDFSTDEELYILRASLSVIQKEGGLINGL
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCEEEEHHHHHHHHHCCCCHHHH
IVVLHDVTEQEKIDRERRQFVANVSHELRTPLTTMKSYLEALADGAWQDKEITPRFIQVV
HHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
QNETERMIRLVNDLLHLSKLDSKDYKLKKTWINFSAYFHKIIDRFELTKSDNIRFVRNIP
HHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC
REAIFIEVDEDKITQVLDNIISNAIKYSPQGGTITFRVRELADEIIISISDEGVGIPKAD
CCEEEEEECHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHHHHEEEECCCCCCCCHHH
LAKIFERFYRVDKARSRKLGGTGLGLAIAKELVIAHGGTIWAESKEHKGTTIYFTLPLER
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCC
EQKDDWYNV
CCCCCCCCC
>Mature Secondary Structure
MKKLGPFRSIHFKFVIIYVLLILIAMQLLGVYFVRKLETELVQNFKNSLNERVTLLAYNV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECH
EQAMSRERDEKSPTLEEDIRSLLHDFVSQDISEVRVIDEKGKVLATSNPYMQNIVGKRTT
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHEEECCCCCEEECCCCHHHHHHCCCHH
EIYVKRSLVTGEIVDRMLLDSKTGYRMYISSTPIKTSGEVKGVIYVIASMENVFSQMRQI
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
NMILATGTGIALAITAVLGIFLSRTITRPISDMRRQALAMTRGDFSRKVKVYGYDEIGQL
HEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHH
AMTFNNLTKKLQEAQATTEGERRKLESVLTHMTDGVIATDRRGRVILINDAALNILNVSR
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCHHHHHHCHH
ETVLSSSIVDVLGIADQYTFETLLEEHDSLILDFSTDEELYILRASLSVIQKEGGLINGL
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCEEEEHHHHHHHHHCCCCHHHH
IVVLHDVTEQEKIDRERRQFVANVSHELRTPLTTMKSYLEALADGAWQDKEITPRFIQVV
HHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
QNETERMIRLVNDLLHLSKLDSKDYKLKKTWINFSAYFHKIIDRFELTKSDNIRFVRNIP
HHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC
REAIFIEVDEDKITQVLDNIISNAIKYSPQGGTITFRVRELADEIIISISDEGVGIPKAD
CCEEEEEECHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHHHHEEEECCCCCCCCHHH
LAKIFERFYRVDKARSRKLGGTGLGLAIAKELVIAHGGTIWAESKEHKGTTIYFTLPLER
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCC
EQKDDWYNV
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]