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The map label for this gene is yusP [H]

Identifier: 138894830

GI number: 138894830

Start: 1233285

End: 1234634

Strand: Direct

Name: yusP [H]

Synonym: GTNG_1164

Alternate gene names: 138894830

Gene position: 1233285-1234634 (Clockwise)

Preceding gene: 138894828

Following gene: 138894831

Centisome position: 34.74

GC content: 50.59

Gene sequence:

>1350_bases
ATGAACAGCCGTCTGTCGGTCATGGTCAGCATCGTGCTGGCGATGCTCGTCGCATCGATGGATACGACGATCATGAACAC
GACCATGCCGATCATCGCTAAGGAACTGGAGGGATTTTCCCTTTATGCGTGGACGTTTGCGTCGTACATGATTACGACAA
CCGTTCTGTCGCCGATTGCCGGTCGCCTGTCGGACTTATTCGGCCGCAAAAAAGTTTTCAGCTTTGGCATTATTTTATTT
TTAATCGGTTCGCTTCTTTGCGGATTGTCGCAAAACATGGTGCAGCTCGTTTTGTTCCGCGCCTTGCAAGGGGTGGGGGC
GGGATTTATGATGCCGTTTCCTGCGATTATTGCCGGTGATTTGTTCCCCGTAGAAAAGCGCGGAAAAATCCAAGCATTTT
TTACTGCCATGTGGGGTCTTTCCGCTGTTTTAGCGCCGCTTTTGGGCTCGCTGTTTGTCGAGTATGCGACATGGCGCTGG
ATTTTTTATGTCAACATTCCGATTTGTGTGCTCTCGCTTTTAACGTTGCTTCCGTATAAAGAAGTGTATGAACCGAAGAG
AGCGGCGATTGACTATGTGGGTGCAGCGCTGTTTGCGACGGCGATCAGCCTGCTTTTGCTCGTCACGGTCGTTGAACAGG
GTCAATGGTGGTATGGTGCGGCTGGGGTGTTGTTGCTTGTCATCTTTTATTATTTCGAAAAACGGCAGCCATCGCCGCTC
GTCCCGTTGTCGCTTGTTCATCACCGGACGCTCAAATGGATGAACATTAACGGGTTTGTCAGCTGCGTCGCCTTGTTTGG
GACGTCAAGCTACATTCCGCTCTTTTTGCAAAATGTTGCCCACTTGTCGGTGTTTATGAGCGGGGTCGCTTTGCTCGGCT
CGTCTGTCGGCTGGATGATCGCCGCTGTGCCGGCGGGGAAATGGATTTTGCGCTATGGTTACCGTTCTCTTCTCATCATC
GGTAACGTGCTACTTGTCGCTTCCGGCCTTTTTCTCGCCTTACTCAACGAGAGCCATGGGTTTTGGTATGTCTTTTTCAT
CATGTTCTTACAAGGGCTGTCGTTTGGCTTGACATCGACCGTTGGCGTCATTGGCTCGCAACAGCTTGCGGATGCTCATG
AAAAGGGGATTGCGACTTCCTTTTTTATGTTTTGCCGCAATATCGGCACAGCGATTGGCGTCACGGTGATGGGAGCGTTT
TTGGCGCAGGCGTCGACATTTATGGCCGGTATTCGTCACCTGTTTTTATTTGGCTTAATCGGCAGCATCATCGCCATGAT
TACCTCACTTTTTATTCGTGATGAAACGGAAGCCGACCGGAACAACCAGCAGTCAGAAGGGATGGCATAA

Upstream 100 bases:

>100_bases
TACAAATGATCCAAATTTTTGACGCATATCATTTTGTGCCATGATTTTTTATCGTGTAAAATAAAATACTTGTAGTTTAC
TAAAAAAGGAGGTTATTTGC

Downstream 100 bases:

>100_bases
AGTCGGGCGGCGTGCCACCGCATGGCCGCCAAAAAAACGGTTAAACATTGGCGGCCATCATCCGATACTATAAGTGGAAC
GACCGATTTCTTTTAAAAAC

Product: permease, MDR related

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MNSRLSVMVSIVLAMLVASMDTTIMNTTMPIIAKELEGFSLYAWTFASYMITTTVLSPIAGRLSDLFGRKKVFSFGIILF
LIGSLLCGLSQNMVQLVLFRALQGVGAGFMMPFPAIIAGDLFPVEKRGKIQAFFTAMWGLSAVLAPLLGSLFVEYATWRW
IFYVNIPICVLSLLTLLPYKEVYEPKRAAIDYVGAALFATAISLLLLVTVVEQGQWWYGAAGVLLLVIFYYFEKRQPSPL
VPLSLVHHRTLKWMNINGFVSCVALFGTSSYIPLFLQNVAHLSVFMSGVALLGSSVGWMIAAVPAGKWILRYGYRSLLII
GNVLLVASGLFLALLNESHGFWYVFFIMFLQGLSFGLTSTVGVIGSQQLADAHEKGIATSFFMFCRNIGTAIGVTVMGAF
LAQASTFMAGIRHLFLFGLIGSIIAMITSLFIRDETEADRNNQQSEGMA

Sequences:

>Translated_449_residues
MNSRLSVMVSIVLAMLVASMDTTIMNTTMPIIAKELEGFSLYAWTFASYMITTTVLSPIAGRLSDLFGRKKVFSFGIILF
LIGSLLCGLSQNMVQLVLFRALQGVGAGFMMPFPAIIAGDLFPVEKRGKIQAFFTAMWGLSAVLAPLLGSLFVEYATWRW
IFYVNIPICVLSLLTLLPYKEVYEPKRAAIDYVGAALFATAISLLLLVTVVEQGQWWYGAAGVLLLVIFYYFEKRQPSPL
VPLSLVHHRTLKWMNINGFVSCVALFGTSSYIPLFLQNVAHLSVFMSGVALLGSSVGWMIAAVPAGKWILRYGYRSLLII
GNVLLVASGLFLALLNESHGFWYVFFIMFLQGLSFGLTSTVGVIGSQQLADAHEKGIATSFFMFCRNIGTAIGVTVMGAF
LAQASTFMAGIRHLFLFGLIGSIIAMITSLFIRDETEADRNNQQSEGMA
>Mature_449_residues
MNSRLSVMVSIVLAMLVASMDTTIMNTTMPIIAKELEGFSLYAWTFASYMITTTVLSPIAGRLSDLFGRKKVFSFGIILF
LIGSLLCGLSQNMVQLVLFRALQGVGAGFMMPFPAIIAGDLFPVEKRGKIQAFFTAMWGLSAVLAPLLGSLFVEYATWRW
IFYVNIPICVLSLLTLLPYKEVYEPKRAAIDYVGAALFATAISLLLLVTVVEQGQWWYGAAGVLLLVIFYYFEKRQPSPL
VPLSLVHHRTLKWMNINGFVSCVALFGTSSYIPLFLQNVAHLSVFMSGVALLGSSVGWMIAAVPAGKWILRYGYRSLLII
GNVLLVASGLFLALLNESHGFWYVFFIMFLQGLSFGLTSTVGVIGSQQLADAHEKGIATSFFMFCRNIGTAIGVTVMGAF
LAQASTFMAGIRHLFLFGLIGSIIAMITSLFIRDETEADRNNQQSEGMA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1790195, Length=414, Percent_Identity=29.951690821256, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1788392, Length=396, Percent_Identity=30.050505050505, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87081983, Length=413, Percent_Identity=24.6973365617433, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789042, Length=302, Percent_Identity=27.8145695364238, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788710, Length=306, Percent_Identity=26.797385620915, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI48994889, Length=131, Percent_Identity=32.0610687022901, Blast_Score=62, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323735, Length=325, Percent_Identity=26.1538461538462, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322958, Length=447, Percent_Identity=23.9373601789709, Blast_Score=106, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6319770, Length=387, Percent_Identity=26.3565891472868, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321663, Length=148, Percent_Identity=33.1081081081081, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6325455, Length=472, Percent_Identity=23.9406779661017, Blast_Score=90, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6324954, Length=232, Percent_Identity=29.7413793103448, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323520, Length=270, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49276; Mature: 49276

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSRLSVMVSIVLAMLVASMDTTIMNTTMPIIAKELEGFSLYAWTFASYMITTTVLSPIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHH
GRLSDLFGRKKVFSFGIILFLIGSLLCGLSQNMVQLVLFRALQGVGAGFMMPFPAIIAGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHCCCHHHHHCC
LFPVEKRGKIQAFFTAMWGLSAVLAPLLGSLFVEYATWRWIFYVNIPICVLSLLTLLPYK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECHHHHHHHHHHCCCH
EVYEPKRAAIDYVGAALFATAISLLLLVTVVEQGQWWYGAAGVLLLVIFYYFEKRQPSPL
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCC
VPLSLVHHRTLKWMNINGFVSCVALFGTSSYIPLFLQNVAHLSVFMSGVALLGSSVGWMI
CCHHHHHHHHHEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHE
AAVPAGKWILRYGYRSLLIIGNVLLVASGLFLALLNESHGFWYVFFIMFLQGLSFGLTST
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHH
VGVIGSQQLADAHEKGIATSFFMFCRNIGTAIGVTVMGAFLAQASTFMAGIRHLFLFGLI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSIIAMITSLFIRDETEADRNNQQSEGMA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]