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The map label for this gene is lytE [H]

Identifier: 138894828

GI number: 138894828

Start: 1230284

End: 1231327

Strand: Direct

Name: lytE [H]

Synonym: GTNG_1162

Alternate gene names: 138894828

Gene position: 1230284-1231327 (Clockwise)

Preceding gene: 138894827

Following gene: 138894830

Centisome position: 34.65

GC content: 48.18

Gene sequence:

>1044_bases
ATGAAAAAAGCACTTGTATTTACCGGGACATTGATCGGATCATTATTAGCCAGCCATGCGGCCTCAGCAGCAAGCCACAC
GGTGCAAAAAGGCGATACGCTCTGGGGAATTTCGAAGAAATATAATACGACCGTCGATCGATTAAAACAACAAAACAATT
TATCTTCCGATCTCATTTTTCCAGGCCAAGTATTGCAAGTAAATGGACAAAGCGGAAGTGGACAAGCAGCTTCCCATACA
TACACTGTCCAGCTCGGTGACACATTAAGCGGGATTGCTAAGAAGTTTGGCACAACGGTAGAAGCGTTGGTCAAACTAAA
CCCAAGCATTACGAATCCGGACTTCATCCGCGACGGCCAAGTGCTCAAAGTAACAGGCGGACAAGAAAACACCAATACAT
ATACTGTTCGGCCGGCGGCCACGGCTGTGAACGGTCAGTACATCGCCCAAAAAGGGGATACATTATCGGAGATTGCGAAC
AAGTTTCAAACGACCGTTGACCGCTTGTTGTCGCTCAATCCGCAAATTACGAACCCGAATATGATTCGCGTTGGCCAAGC
CATTAAAGTAACGGGTGGAACAACCGCTGTTCGCACCGAGCAACAAGGATCGACCGCCCAACAAACGAAACCGGCCGCTA
AACCGGCTGCGTCTGAATCGTCTGCTTCACTTGCCGACAAAATCATCAAAATCGGCGAAAAATATTTAGGGGCGAGATAT
TTGTACGGAGCAGATCCATCGCGCACCGATGTGTTCGACTGCTCTTCGTTTACAATGCGTGTTTTTAGCGAAGCAGGCAT
TTCGCTGCCGCGTACATCGTCAGCCCAAGCACAAGCCGGCAAAGCGGTGTCGTTCAACCAATTGCAAAAAGGTGATCTTG
TCTTTTTTGACACTGACTCGAACGGCACGATCAACCATGTTGGCATTTACGCTGGCAATGGGCAAATGATTAATGCGACT
GTTTCGTTGGGCGTTACGTATTCGTCGCTCACTTCATCGTATTGGAAAACGCGGTTTGTAAAGGCGGTTCGCGTGCTTAA
CTAA

Upstream 100 bases:

>100_bases
GGCTCATGTGCGGGAATACATGGCGATTTTTGTAGAGTGATAGCGAAATTTACCTAAGGAAATAGAGAAATGTCAAATTG
ATGTCATAGGGGGATATAAA

Downstream 100 bases:

>100_bases
CGGGATGCTTACGGACATTTTGCCTGTTGCTTAAACATAGCCGAATGCGACAGAAGGCTGCTCGCATAAAGCACATGTGA
GGCTTTAGCGGGCAGCTTTT

Product: phosphatase-associated protein

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP33; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytE; Phosphatase-associated protein papQ [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKKALVFTGTLIGSLLASHAASAASHTVQKGDTLWGISKKYNTTVDRLKQQNNLSSDLIFPGQVLQVNGQSGSGQAASHT
YTVQLGDTLSGIAKKFGTTVEALVKLNPSITNPDFIRDGQVLKVTGGQENTNTYTVRPAATAVNGQYIAQKGDTLSEIAN
KFQTTVDRLLSLNPQITNPNMIRVGQAIKVTGGTTAVRTEQQGSTAQQTKPAAKPAASESSASLADKIIKIGEKYLGARY
LYGADPSRTDVFDCSSFTMRVFSEAGISLPRTSSAQAQAGKAVSFNQLQKGDLVFFDTDSNGTINHVGIYAGNGQMINAT
VSLGVTYSSLTSSYWKTRFVKAVRVLN

Sequences:

>Translated_347_residues
MKKALVFTGTLIGSLLASHAASAASHTVQKGDTLWGISKKYNTTVDRLKQQNNLSSDLIFPGQVLQVNGQSGSGQAASHT
YTVQLGDTLSGIAKKFGTTVEALVKLNPSITNPDFIRDGQVLKVTGGQENTNTYTVRPAATAVNGQYIAQKGDTLSEIAN
KFQTTVDRLLSLNPQITNPNMIRVGQAIKVTGGTTAVRTEQQGSTAQQTKPAAKPAASESSASLADKIIKIGEKYLGARY
LYGADPSRTDVFDCSSFTMRVFSEAGISLPRTSSAQAQAGKAVSFNQLQKGDLVFFDTDSNGTINHVGIYAGNGQMINAT
VSLGVTYSSLTSSYWKTRFVKAVRVLN
>Mature_347_residues
MKKALVFTGTLIGSLLASHAASAASHTVQKGDTLWGISKKYNTTVDRLKQQNNLSSDLIFPGQVLQVNGQSGSGQAASHT
YTVQLGDTLSGIAKKFGTTVEALVKLNPSITNPDFIRDGQVLKVTGGQENTNTYTVRPAATAVNGQYIAQKGDTLSEIAN
KFQTTVDRLLSLNPQITNPNMIRVGQAIKVTGGTTAVRTEQQGSTAQQTKPAAKPAASESSASLADKIIKIGEKYLGARY
LYGADPSRTDVFDCSSFTMRVFSEAGISLPRTSSAQAQAGKAVSFNQLQKGDLVFFDTDSNGTINHVGIYAGNGQMINAT
VSLGVTYSSLTSSYWKTRFVKAVRVLN

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG1388

COG function: function code M; FOG: LysM repeat

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1788501, Length=159, Percent_Identity=35.8490566037736, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788001, Length=138, Percent_Identity=38.4057971014493, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787944, Length=115, Percent_Identity=34.7826086956522, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 36872; Mature: 36872

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKALVFTGTLIGSLLASHAASAASHTVQKGDTLWGISKKYNTTVDRLKQQNNLSSDLIF
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCEEC
PGQVLQVNGQSGSGQAASHTYTVQLGDTLSGIAKKFGTTVEALVKLNPSITNPDFIRDGQ
CCEEEEEECCCCCCCCCCEEEEEEECCHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCC
VLKVTGGQENTNTYTVRPAATAVNGQYIAQKGDTLSEIANKFQTTVDRLLSLNPQITNPN
EEEEECCCCCCCEEEEECCCEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
MIRVGQAIKVTGGTTAVRTEQQGSTAQQTKPAAKPAASESSASLADKIIKIGEKYLGARY
EEEECCEEEECCCCEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEE
LYGADPSRTDVFDCSSFTMRVFSEAGISLPRTSSAQAQAGKAVSFNQLQKGDLVFFDTDS
EECCCCCCCCEECCCHHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHCCCCCEEEEECCC
NGTINHVGIYAGNGQMINATVSLGVTYSSLTSSYWKTRFVKAVRVLN
CCCEEEEEEEECCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKALVFTGTLIGSLLASHAASAASHTVQKGDTLWGISKKYNTTVDRLKQQNNLSSDLIF
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCEEC
PGQVLQVNGQSGSGQAASHTYTVQLGDTLSGIAKKFGTTVEALVKLNPSITNPDFIRDGQ
CCEEEEEECCCCCCCCCCEEEEEEECCHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCC
VLKVTGGQENTNTYTVRPAATAVNGQYIAQKGDTLSEIANKFQTTVDRLLSLNPQITNPN
EEEEECCCCCCCEEEEECCCEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
MIRVGQAIKVTGGTTAVRTEQQGSTAQQTKPAAKPAASESSASLADKIIKIGEKYLGARY
EEEECCEEEECCCCEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEE
LYGADPSRTDVFDCSSFTMRVFSEAGISLPRTSSAQAQAGKAVSFNQLQKGDLVFFDTDS
EECCCCCCCCEECCCHHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHCCCCCEEEEECCC
NGTINHVGIYAGNGQMINATVSLGVTYSSLTSSYWKTRFVKAVRVLN
CCCEEEEEEEECCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457885; 9579061; 9384377; 8045898 [H]