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The map label for this gene is pyrH [H]

Identifier: 138894771

GI number: 138894771

Start: 1165554

End: 1166351

Strand: Direct

Name: pyrH [H]

Synonym: GTNG_1105

Alternate gene names: 138894771

Gene position: 1165554-1166351 (Clockwise)

Preceding gene: 138894770

Following gene: 138894772

Centisome position: 32.83

GC content: 51.63

Gene sequence:

>798_bases
ATGACGGACCGCAACAGGGAACACGCTCGTGTTCCCTGTTTTTCAAAGCGACTCGCATCATCACGGAGGTTTGACATGGA
ACAACCAAAATACAAACGCGTTGTTTTAAAGCTAAGCGGAGAAGCGCTCGCCGGAAAACAAGGATTTGGCATCCAGCCGG
CAGTGATCCAGTCGATCGCCAAACAAGTAAAAGAAGTGGCTGAACTCGATGTGGAAATCGCCATCGTTGTCGGCGGCGGC
AACATTTGGCGCGGAAAAACAGGAAGCGAAATGGGAATGGACCGGGCGACAGCTGACTACATGGGGATGTTAGCGACGGT
AATGAACGCGCTCGCCTTGCAGGATAGCCTCGAGCAGCTCGGCGTCGAAACGCGGGTGCAGACATCGATTGAAATGAGAC
AAGTGGCCGAACCGTACATCCGTCGGCGGGCGATTCGCCATCTCGAGAAAAAGCGGGTCGTCATTTTCGCCGCTGGTACG
GGCAACCCATATTTTTCAACCGATACGACTGCCGCGCTGCGGGCAGCAGAAATTGAAGCGGACGTCATTTTGATGGCGAA
AAACAACGTTGACGGCGTCTATAGTGCCGATCCGAATATCGATGCCAGTGCGGTCAAATACGATGAACTGTCGTACTTGG
ATGTCATTCAGCAAGGGCTCGGTGTCATGGACTCTACCGCTTCCTCGCTTTGCATGGACAACAATATTCCACTCATCGTC
TTTTCGATTACGGAAGAGGGTAACATTAAACGTGCTGTATTAGGAGAAAATATCGGAACGATCGTAAGGGGGAAATAA

Upstream 100 bases:

>100_bases
GAGCAACCGTGAAGCAGTTCATCCGCTACGAAGTTGGTGAAGGGCTCGAAAAACGTCAAGATAATTTCGCTGAAGAAGTC
ATGAGCCAAGTAAGAAAACA

Downstream 100 bases:

>100_bases
CGATGGCAAAGCAAGTGATCCAACAGGCGAAAGAAAAAATGGATAAAGCTGTGCAAGCGTTCAGCCGCGAGTTGGCGACC
GTCCGTGCCGGTCGGGCGAA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTDRNREHARVPCFSKRLASSRRFDMEQPKYKRVVLKLSGEALAGKQGFGIQPAVIQSIAKQVKEVAELDVEIAIVVGGG
NIWRGKTGSEMGMDRATADYMGMLATVMNALALQDSLEQLGVETRVQTSIEMRQVAEPYIRRRAIRHLEKKRVVIFAAGT
GNPYFSTDTTAALRAAEIEADVILMAKNNVDGVYSADPNIDASAVKYDELSYLDVIQQGLGVMDSTASSLCMDNNIPLIV
FSITEEGNIKRAVLGENIGTIVRGK

Sequences:

>Translated_265_residues
MTDRNREHARVPCFSKRLASSRRFDMEQPKYKRVVLKLSGEALAGKQGFGIQPAVIQSIAKQVKEVAELDVEIAIVVGGG
NIWRGKTGSEMGMDRATADYMGMLATVMNALALQDSLEQLGVETRVQTSIEMRQVAEPYIRRRAIRHLEKKRVVIFAAGT
GNPYFSTDTTAALRAAEIEADVILMAKNNVDGVYSADPNIDASAVKYDELSYLDVIQQGLGVMDSTASSLCMDNNIPLIV
FSITEEGNIKRAVLGENIGTIVRGK
>Mature_264_residues
TDRNREHARVPCFSKRLASSRRFDMEQPKYKRVVLKLSGEALAGKQGFGIQPAVIQSIAKQVKEVAELDVEIAIVVGGGN
IWRGKTGSEMGMDRATADYMGMLATVMNALALQDSLEQLGVETRVQTSIEMRQVAEPYIRRRAIRHLEKKRVVIFAAGTG
NPYFSTDTTAALRAAEIEADVILMAKNNVDGVYSADPNIDASAVKYDELSYLDVIQQGLGVMDSTASSLCMDNNIPLIVF
SITEEGNIKRAVLGENIGTIVRGK

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=235, Percent_Identity=45.9574468085106, Blast_Score=229, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 28999; Mature: 28868

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRNREHARVPCFSKRLASSRRFDMEQPKYKRVVLKLSGEALAGKQGFGIQPAVIQSIA
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHEEEEEEECCCEECCCCCCCCCHHHHHHHH
KQVKEVAELDVEIAIVVGGGNIWRGKTGSEMGMDRATADYMGMLATVMNALALQDSLEQL
HHHHHHHHCCEEEEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GVETRVQTSIEMRQVAEPYIRRRAIRHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHEECCC
DVILMAKNNVDGVYSADPNIDASAVKYDELSYLDVIQQGLGVMDSTASSLCMDNNIPLIV
CEEEEEECCCCEEEECCCCCCHHHEEHHHHHHHHHHHHHCCCHHHHHHHHEECCCCCEEE
FSITEEGNIKRAVLGENIGTIVRGK
EEECCCCCEEEEECCCCCCEEEECC
>Mature Secondary Structure 
TDRNREHARVPCFSKRLASSRRFDMEQPKYKRVVLKLSGEALAGKQGFGIQPAVIQSIA
CCCCCCCCCCCHHHHHHHHHCCCCCCCCHHEEEEEEECCCEECCCCCCCCCHHHHHHHH
KQVKEVAELDVEIAIVVGGGNIWRGKTGSEMGMDRATADYMGMLATVMNALALQDSLEQL
HHHHHHHHCCEEEEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GVETRVQTSIEMRQVAEPYIRRRAIRHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHEECCC
DVILMAKNNVDGVYSADPNIDASAVKYDELSYLDVIQQGLGVMDSTASSLCMDNNIPLIV
CEEEEEECCCCEEEECCCCCCHHHEEHHHHHHHHHHHHHCCCHHHHHHHHEECCCCCEEE
FSITEEGNIKRAVLGENIGTIVRGK
EEECCCCCEEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA