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The map label for this gene is tsf [H]

Identifier: 138894770

GI number: 138894770

Start: 1164673

End: 1165557

Strand: Direct

Name: tsf [H]

Synonym: GTNG_1104

Alternate gene names: 138894770

Gene position: 1164673-1165557 (Clockwise)

Preceding gene: 138894769

Following gene: 138894771

Centisome position: 32.8

GC content: 48.7

Gene sequence:

>885_bases
ATGGCGATTACAGCACAAATGGTAAAAGAGCTGCGCGAAAAAACGGGCGCAGGCATGATGGACTGCAAAAAAGCGCTCAC
CGAAACGAACGGTGACATGGAAAAAGCGATCGACTGGCTGCGTGAAAAAGGAATTGCTAAAGCAGCGAAAAAAGCAGATC
GCATCGCAGCGGAAGGAATGACATACATCGCGACGGAAGGCAATGCGGCTGTCATTTTGGAAGTAAACTCGGAAACGGAC
TTCGTTGCCAAAAACGAAGCGTTCCAAACGCTCGTTAAGGAGCTGGCTGCACATCTGCTGAAACAAAAGCCAGCCACGCT
TGATGAAGCGCTCGGACAAACGATGAGCAGTGGTTCCACTGTTCAAGATTACATTAACGAAGCAGTTGCTAAAATCGGTG
AAAAAATTACGCTCCGCCGCTTTGCTGTTGTCAACAAAGCGGATGATGAAACGTTTGGCGCGTACTTGCACATGGGCGGG
CGCATCGGCGTATTAACATTATTAGCCGGCAGCGCAACTGAAGAGGTCGCTAAAGATGTGGCGATGCATATTGCTGCGCT
CCATCCGAAATACGTTTCGCGCGATGAAGTGCCGCAAGAAGAGATTGCGCGCGAACGTGAAGTGTTGAAACAACAAGCGT
TGAACGAAGGTAAGCCGGAAAACATCGTTGAAAAAATGGTTGAAGGCCGTCTGAAAAAGTTTTACGAAGATGTTTGCCTG
CTTGAGCAAGCGTTCGTGAAAAACCCGGATGTGACGGTACGCCAATACGTCGAATCGAGCGGAGCAACCGTGAAGCAGTT
CATCCGCTACGAAGTTGGTGAAGGGCTCGAAAAACGTCAAGATAATTTCGCTGAAGAAGTCATGAGCCAAGTAAGAAAAC
AATGA

Upstream 100 bases:

>100_bases
GAAATCAGCAACTTTTGGCTATACTAACGAATAAGGGCAAAACAGGCACCCGCTGCCGACATCGATACATATATGGGATA
AAGAGAAGGAGGAGCTTTTC

Downstream 100 bases:

>100_bases
CGGACCGCAACAGGGAACACGCTCGTGTTCCCTGTTTTTCAAAGCGACTCGCATCATCACGGAGGTTTGACATGGAACAA
CCAAAATACAAACGCGTTGT

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MAITAQMVKELREKTGAGMMDCKKALTETNGDMEKAIDWLREKGIAKAAKKADRIAAEGMTYIATEGNAAVILEVNSETD
FVAKNEAFQTLVKELAAHLLKQKPATLDEALGQTMSSGSTVQDYINEAVAKIGEKITLRRFAVVNKADDETFGAYLHMGG
RIGVLTLLAGSATEEVAKDVAMHIAALHPKYVSRDEVPQEEIAREREVLKQQALNEGKPENIVEKMVEGRLKKFYEDVCL
LEQAFVKNPDVTVRQYVESSGATVKQFIRYEVGEGLEKRQDNFAEEVMSQVRKQ

Sequences:

>Translated_294_residues
MAITAQMVKELREKTGAGMMDCKKALTETNGDMEKAIDWLREKGIAKAAKKADRIAAEGMTYIATEGNAAVILEVNSETD
FVAKNEAFQTLVKELAAHLLKQKPATLDEALGQTMSSGSTVQDYINEAVAKIGEKITLRRFAVVNKADDETFGAYLHMGG
RIGVLTLLAGSATEEVAKDVAMHIAALHPKYVSRDEVPQEEIAREREVLKQQALNEGKPENIVEKMVEGRLKKFYEDVCL
LEQAFVKNPDVTVRQYVESSGATVKQFIRYEVGEGLEKRQDNFAEEVMSQVRKQ
>Mature_293_residues
AITAQMVKELREKTGAGMMDCKKALTETNGDMEKAIDWLREKGIAKAAKKADRIAAEGMTYIATEGNAAVILEVNSETDF
VAKNEAFQTLVKELAAHLLKQKPATLDEALGQTMSSGSTVQDYINEAVAKIGEKITLRRFAVVNKADDETFGAYLHMGGR
IGVLTLLAGSATEEVAKDVAMHIAALHPKYVSRDEVPQEEIAREREVLKQQALNEGKPENIVEKMVEGRLKKFYEDVCLL
EQAFVKNPDVTVRQYVESSGATVKQFIRYEVGEGLEKRQDNFAEEVMSQVRKQ

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Homo sapiens, GI171846268, Length=304, Percent_Identity=27.6315789473684, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI291084500, Length=325, Percent_Identity=26.1538461538462, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI291084502, Length=114, Percent_Identity=39.4736842105263, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI291084498, Length=114, Percent_Identity=39.4736842105263, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI1786366, Length=289, Percent_Identity=46.0207612456747, Blast_Score=229, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17561440, Length=300, Percent_Identity=27.6666666666667, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI19921466, Length=284, Percent_Identity=27.112676056338, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 32588; Mature: 32456

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS01126 EF_TS_1 ; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITAQMVKELREKTGAGMMDCKKALTETNGDMEKAIDWLREKGIAKAAKKADRIAAEGM
CCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TYIATEGNAAVILEVNSETDFVAKNEAFQTLVKELAAHLLKQKPATLDEALGQTMSSGST
EEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCH
VQDYINEAVAKIGEKITLRRFAVVNKADDETFGAYLHMGGRIGVLTLLAGSATEEVAKDV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHH
AMHIAALHPKYVSRDEVPQEEIAREREVLKQQALNEGKPENIVEKMVEGRLKKFYEDVCL
HHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LEQAFVKNPDVTVRQYVESSGATVKQFIRYEVGEGLEKRQDNFAEEVMSQVRKQ
HHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AITAQMVKELREKTGAGMMDCKKALTETNGDMEKAIDWLREKGIAKAAKKADRIAAEGM
CCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TYIATEGNAAVILEVNSETDFVAKNEAFQTLVKELAAHLLKQKPATLDEALGQTMSSGST
EEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCH
VQDYINEAVAKIGEKITLRRFAVVNKADDETFGAYLHMGGRIGVLTLLAGSATEEVAKDV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHH
AMHIAALHPKYVSRDEVPQEEIAREREVLKQQALNEGKPENIVEKMVEGRLKKFYEDVCL
HHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LEQAFVKNPDVTVRQYVESSGATVKQFIRYEVGEGLEKRQDNFAEEVMSQVRKQ
HHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA