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The map label for this gene is hemN [C]

Identifier: 138894501

GI number: 138894501

Start: 903236

End: 905029

Strand: Reverse

Name: hemN [C]

Synonym: GTNG_0831

Alternate gene names: 138894501

Gene position: 905029-903236 (Counterclockwise)

Preceding gene: 138894504

Following gene: 138894491

Centisome position: 25.49

GC content: 50.56

Gene sequence:

>1794_bases
ATGAAAAGGAGTTTTGCTACGATGAACGTTGTCTGTACGACATTAAATGCCAAATACATTCATATGAATTTAGCCATTCG
CTATTTAAAAGCATACGCCCAGCCGGAGTTTGACGTCAAGCTTGTTGAATATACGATTAAAGACCCAGCGATGAACATCG
TTGCTGATTTGTATCAGCAACAACCGGATGTCGTCGGCTTCAGCTGTTACATTTGGAACATTGAAGAAACGATCAAAGTC
GTAAAAATGTTAAAAAAAGTGGCGCCGGACGTGACGGTCGTCGTTGGTGGGCCGGAAGTGTCTTATGATGTGCGCGAATG
GATGGAGCGAGTGCCGGAATTCGATTTTATCGTCATCGGTGAAGGAGAAGAAACGTTTAAACAGCTGCTGTTCGCCTTAA
ACGGCGATGGGAACGTGAGCGATGTCGCTGGGCTGGCGTTTCGTGACGGAGATCGCATCGTCGTCAACCCGCAACGGAAC
AAAATCCGCCTTGCCGACATGCCGTCGCCGTTTCGCTTTCCCGAAGATCTTCCGCATCTTCCGAACCGGATCGTTTATGT
CGAGACAAGCCGCGGCTGCCCGTTCAGCTGCCAATTTTGCCTGTCGTCCATCGAGGTTGGTGTCCGCTATTTTGACCGCG
AAAAAATCAAAGATGACTTGCGTTATTTAATGCAGCACGGGGCGCGGACGATCAAGTTTGTCGATCGGACGTTCAACATC
AGCCGCAGCTATGCGATGGATATGTTCCGCTTTTTAATTGACGAGCACGTGCCGGGGACGGTGTTTCAGTTTGAAATTAC
CGCCGACATTATGCGTCCTGAGGTGATCGAGTTTTTAAACAACGAGGCACCACCGGGGCTATTCCGCTTTGAAATCGGCG
TTCAGTCAACGAACGATGAAGTGAACCGTCTCATCATGCGCAAACAAAACTTCGCGAAACTGTCGCGGACGGTGACGATG
ATTAAAGAGGGAGGGAAAATTACCCAGCACTTAGATTTGATCGCCGGGCTGCCGGAAGAAGATTACGACTCGTTTCGGAA
GACGTTCAATGACGTATTCGCCCTCCGTCCGGAAGAACTGCAGCTTGGGTTTTTGAAACTGCTGCGCGGCACTGGGTTGC
GCCTGCGCGCTCATGAATACGGCTATGTATATATGGATCATGCGCCGTATGAAGTGCTTCGCAACAACGTTTTGTCTTTT
GATGACGTCATCCGCATCAAGCAAGTGGAAGATGTGCTCGAAAAGTATTGGAACGCCCATCGGATGGATGAAACGATCGA
ATATTTAGTAACCGACGTCTTCCCGTCACCGTTTGACTTCTTCCAGCAGTTTGGAACATATTGGGATGAACGCGGCTGGG
CGCGCATCGGTCATCAGTTAGAAGACTTGTTCCGCCGCCTCTATGAGTTTTTACGTACATCGGTACCAGACGCCTTGCCT
GTCGCCGAATCGCTCATGAAATACGACTACTTGCGCAATCAAAAATATAAGCCGCGCAAGCCGTGGTGGGACGAAAAAAC
AGAGAAAACGACGCGCACAGCCGTCTACCGGACGTTGCTTGAGCGCCCTGAGGTGCTCGGGGCGGACTTCGCCGCCCTTG
GGCTCGGAGAAAAAGAGCTGTTTAAACATACGGTCGTTGAAATCGTGCCGGTCGATGTCGGCCTCTACATTTCTAAAAGG
CAGCTTTCGTTTACGCCAACCGTTATCGTCGCCTACTTTGACCCGTCCGGTGCCGGTGCGACCATGTTTTCCGTGCCGCT
TTCCTCATTGTCGGCTTCTTTCACGTCGGCTTAA

Upstream 100 bases:

>100_bases
CCATTCACGAAGATTTTTCAAAAATCTTTTCCTCAATGTTCGACAAGTTTTTTCTTCTTTTTCATTTGGCTAAACTGCAT
TATAATGTGGGGTTAGTACG

Downstream 100 bases:

>100_bases
ACCGGAGGAACTAAACGGCCCTTGGCTTCATTTCATACCATTCCGTCTGCCCATCAAAAACGGCAGACAGTGAACAGGCA
CTGACAATCCTTCGTTTCCG

Product: Mg-protoporphyrin IX monomethyl ester oxidativecyclase

Products: Protoporphyrinogen-IX; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MKRSFATMNVVCTTLNAKYIHMNLAIRYLKAYAQPEFDVKLVEYTIKDPAMNIVADLYQQQPDVVGFSCYIWNIEETIKV
VKMLKKVAPDVTVVVGGPEVSYDVREWMERVPEFDFIVIGEGEETFKQLLFALNGDGNVSDVAGLAFRDGDRIVVNPQRN
KIRLADMPSPFRFPEDLPHLPNRIVYVETSRGCPFSCQFCLSSIEVGVRYFDREKIKDDLRYLMQHGARTIKFVDRTFNI
SRSYAMDMFRFLIDEHVPGTVFQFEITADIMRPEVIEFLNNEAPPGLFRFEIGVQSTNDEVNRLIMRKQNFAKLSRTVTM
IKEGGKITQHLDLIAGLPEEDYDSFRKTFNDVFALRPEELQLGFLKLLRGTGLRLRAHEYGYVYMDHAPYEVLRNNVLSF
DDVIRIKQVEDVLEKYWNAHRMDETIEYLVTDVFPSPFDFFQQFGTYWDERGWARIGHQLEDLFRRLYEFLRTSVPDALP
VAESLMKYDYLRNQKYKPRKPWWDEKTEKTTRTAVYRTLLERPEVLGADFAALGLGEKELFKHTVVEIVPVDVGLYISKR
QLSFTPTVIVAYFDPSGAGATMFSVPLSSLSASFTSA

Sequences:

>Translated_597_residues
MKRSFATMNVVCTTLNAKYIHMNLAIRYLKAYAQPEFDVKLVEYTIKDPAMNIVADLYQQQPDVVGFSCYIWNIEETIKV
VKMLKKVAPDVTVVVGGPEVSYDVREWMERVPEFDFIVIGEGEETFKQLLFALNGDGNVSDVAGLAFRDGDRIVVNPQRN
KIRLADMPSPFRFPEDLPHLPNRIVYVETSRGCPFSCQFCLSSIEVGVRYFDREKIKDDLRYLMQHGARTIKFVDRTFNI
SRSYAMDMFRFLIDEHVPGTVFQFEITADIMRPEVIEFLNNEAPPGLFRFEIGVQSTNDEVNRLIMRKQNFAKLSRTVTM
IKEGGKITQHLDLIAGLPEEDYDSFRKTFNDVFALRPEELQLGFLKLLRGTGLRLRAHEYGYVYMDHAPYEVLRNNVLSF
DDVIRIKQVEDVLEKYWNAHRMDETIEYLVTDVFPSPFDFFQQFGTYWDERGWARIGHQLEDLFRRLYEFLRTSVPDALP
VAESLMKYDYLRNQKYKPRKPWWDEKTEKTTRTAVYRTLLERPEVLGADFAALGLGEKELFKHTVVEIVPVDVGLYISKR
QLSFTPTVIVAYFDPSGAGATMFSVPLSSLSASFTSA
>Mature_597_residues
MKRSFATMNVVCTTLNAKYIHMNLAIRYLKAYAQPEFDVKLVEYTIKDPAMNIVADLYQQQPDVVGFSCYIWNIEETIKV
VKMLKKVAPDVTVVVGGPEVSYDVREWMERVPEFDFIVIGEGEETFKQLLFALNGDGNVSDVAGLAFRDGDRIVVNPQRN
KIRLADMPSPFRFPEDLPHLPNRIVYVETSRGCPFSCQFCLSSIEVGVRYFDREKIKDDLRYLMQHGARTIKFVDRTFNI
SRSYAMDMFRFLIDEHVPGTVFQFEITADIMRPEVIEFLNNEAPPGLFRFEIGVQSTNDEVNRLIMRKQNFAKLSRTVTM
IKEGGKITQHLDLIAGLPEEDYDSFRKTFNDVFALRPEELQLGFLKLLRGTGLRLRAHEYGYVYMDHAPYEVLRNNVLSF
DDVIRIKQVEDVLEKYWNAHRMDETIEYLVTDVFPSPFDFFQQFGTYWDERGWARIGHQLEDLFRRLYEFLRTSVPDALP
VAESLMKYDYLRNQKYKPRKPWWDEKTEKTTRTAVYRTLLERPEVLGADFAALGLGEKELFKHTVVEIVPVDVGLYISKR
QLSFTPTVIVAYFDPSGAGATMFSVPLSSLSASFTSA

Specific function: Anaerobic Transformation Of Coproporphyrinogen-III Into Protoporphyrinogen-IX. [C]

COG id: COG1032

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B12-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR007197 [H]

Pfam domain/function: PF02310 B12-binding; PF04055 Radical_SAM [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 69119; Mature: 69119

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSFATMNVVCTTLNAKYIHMNLAIRYLKAYAQPEFDVKLVEYTIKDPAMNIVADLYQQ
CCCCCEEHEEEEEECCCEEEEHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHC
QPDVVGFSCYIWNIEETIKVVKMLKKVAPDVTVVVGGPEVSYDVREWMERVPEFDFIVIG
CCCEEEEEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEC
EGEETFKQLLFALNGDGNVSDVAGLAFRDGDRIVVNPQRNKIRLADMPSPFRFPEDLPHL
CCHHHHHHHHHHCCCCCCHHHHCCEEEECCCEEEECCCCCEEEEECCCCCCCCCCCCCCC
PNRIVYVETSRGCPFSCQFCLSSIEVGVRYFDREKIKDDLRYLMQHGARTIKFVDRTFNI
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCC
SRSYAMDMFRFLIDEHVPGTVFQFEITADIMRPEVIEFLNNEAPPGLFRFEIGVQSTNDE
HHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHH
VNRLIMRKQNFAKLSRTVTMIKEGGKITQHLDLIAGLPEEDYDSFRKTFNDVFALRPEEL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHH
QLGFLKLLRGTGLRLRAHEYGYVYMDHAPYEVLRNNVLSFDDVIRIKQVEDVLEKYWNAH
HHHHHHHHHCCCCEEEEEECCEEEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHH
RMDETIEYLVTDVFPSPFDFFQQFGTYWDERGWARIGHQLEDLFRRLYEFLRTSVPDALP
HHHHHHHHHHHHCCCCHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VAESLMKYDYLRNQKYKPRKPWWDEKTEKTTRTAVYRTLLERPEVLGADFAALGLGEKEL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCHHHHCCCHHHH
FKHTVVEIVPVDVGLYISKRQLSFTPTVIVAYFDPSGAGATMFSVPLSSLSASFTSA
HHHHHHEEEEECCCEEEECCEEECCCEEEEEEECCCCCCCEEEECCHHHHHHHHCCC
>Mature Secondary Structure
MKRSFATMNVVCTTLNAKYIHMNLAIRYLKAYAQPEFDVKLVEYTIKDPAMNIVADLYQQ
CCCCCEEHEEEEEECCCEEEEHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHC
QPDVVGFSCYIWNIEETIKVVKMLKKVAPDVTVVVGGPEVSYDVREWMERVPEFDFIVIG
CCCEEEEEEEEECHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEC
EGEETFKQLLFALNGDGNVSDVAGLAFRDGDRIVVNPQRNKIRLADMPSPFRFPEDLPHL
CCHHHHHHHHHHCCCCCCHHHHCCEEEECCCEEEECCCCCEEEEECCCCCCCCCCCCCCC
PNRIVYVETSRGCPFSCQFCLSSIEVGVRYFDREKIKDDLRYLMQHGARTIKFVDRTFNI
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCC
SRSYAMDMFRFLIDEHVPGTVFQFEITADIMRPEVIEFLNNEAPPGLFRFEIGVQSTNDE
HHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHH
VNRLIMRKQNFAKLSRTVTMIKEGGKITQHLDLIAGLPEEDYDSFRKTFNDVFALRPEEL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHH
QLGFLKLLRGTGLRLRAHEYGYVYMDHAPYEVLRNNVLSFDDVIRIKQVEDVLEKYWNAH
HHHHHHHHHCCCCEEEEEECCEEEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHH
RMDETIEYLVTDVFPSPFDFFQQFGTYWDERGWARIGHQLEDLFRRLYEFLRTSVPDALP
HHHHHHHHHHHHCCCCHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VAESLMKYDYLRNQKYKPRKPWWDEKTEKTTRTAVYRTLLERPEVLGADFAALGLGEKEL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCHHHHCCCHHHH
FKHTVVEIVPVDVGLYISKRQLSFTPTVIVAYFDPSGAGATMFSVPLSSLSASFTSA
HHHHHHEEEEECCCEEEECCEEECCCEEEEEEECCCCCCCEEEECCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen-III; O2 [C]

Specific reaction: coproporphyrinogen-III + O2 = protoporphyrinogen-IX + 2 CO2 [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With oxygen as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]