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The map label for this gene is sucC [H]

Identifier: 134302424

GI number: 134302424

Start: 1467951

End: 1469114

Strand: Direct

Name: sucC [H]

Synonym: FTW_1561

Alternate gene names: 134302424

Gene position: 1467951-1469114 (Clockwise)

Preceding gene: 134302420

Following gene: 134302425

Centisome position: 77.32

GC content: 37.8

Gene sequence:

>1164_bases
ATGAACTTACATGAATATCAAGCTAAAGATCTTTTAGAAAGCTATGGTCTAAAAGTTCAAAAAGGTATCGTAGCTCATAA
CCCAAATGAAGCTGCTCAAGCATTTGACCAATTAGGTGGCAAATTTGCTGTGGTTAAAGCTCAGGTACATGCTGGTGGTC
GTGGTAAAGCTGGTGGTGTAAAGGTTGTTAAATCATCTCAAGAAGCTCGTGAAGTAGCAGAAAGCTTAATCGGTAAAAAT
CTTGTTACTTTCCAAACTGATGCTGAAGGTCAGCCAGTTAATTCTGTAGGTGTATTTGAAGATGTATACCCTGTTACTCG
TGAGTTATACCTTGGTGCGGTAGTTGATAGATCTAGCCGTAAAGTAACATTCATGGCTTCAACTGAAGGCGGTGTAGATA
TTGAAGAAGTTGCACACAACTCTCCTGAAAAAATCCTTAAAGTAGAAGTAGATCCTTTAGTTGGCTTACAACCTTTCCAA
GCTCGTGAAGTAGCTTTCAAGCTTGGTCTAGAAGGCAAGCAAATCAATGATTTTGTTAAAACTATGCTAGGCGCTTACAA
AGCATTCATCGAATGTGATTTTGCCCTATTTGAAATCAACCCTCTTGCAGTTAGAGAAAACGGAGAGATTGTCTGTGTTG
ATGGTAAAATCAACCTTGATTCAAATGCTCTTTATAGACACCCTAAACTTTTAGCTCTAAGAGACAAATCTCAAGAAAAT
GCTAAAGAACTTAAAGCTTCAGAGCATGAGCTAAACTATGTAGCTCTTAAAGGTAACATCGGTTGTATGGTAAACGGTGC
TGGTCTAGCAATGGCTACTATGGATATTATCCAATTATACGGTGGTAAGCCTGCTAACTTCCTAGATGTAGGTGGTGGTG
CTACTAAAGAGAGAGTAATCGAAGCTTTCAAACTAATCCTAGATGATGAAAATGTAAAAGCTGTTTTAATTAACATCTTC
GGTGGTATTGTTCGTTGTGATATGATCGCTGAAGCAATTATTGAAGCTGTTAAAGAAGTAAATGTAACTGTACCAGTAGT
TGTTCGTCTAGAAGGTAACAATGCAGAAAAAGGTGCTAAAATATTAGCTGATTCAGGTTTAAAACTAATACCTGCTGATG
GTTTAGCTGATGCTGCTGATAAAGTTGTGAAATCACTAGGTTAA

Upstream 100 bases:

>100_bases
AATAAGTATTTTTATTAGAAAAAATAACATAAATGAGTTATTATTTTGTTTGTTATCTAATAAAAATTTTCATCAAACTA
TCAAATAAGGAAGAAAATCA

Downstream 100 bases:

>100_bases
TAAATTAAAACAGTTAAAAGGATATTAAATAATGAGCGTATTAGTTGATAAAAATACAAAAGTTTTAGTACAGGGTTTTA
CTGGTAAAAATGGTACTTTC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGVKVVKSSQEAREVAESLIGKN
LVTFQTDAEGQPVNSVGVFEDVYPVTRELYLGAVVDRSSRKVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQ
AREVAFKLGLEGKQINDFVKTMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQEN
AKELKASEHELNYVALKGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVIEAFKLILDDENVKAVLINIF
GGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAKILADSGLKLIPADGLADAADKVVKSLG

Sequences:

>Translated_387_residues
MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGVKVVKSSQEAREVAESLIGKN
LVTFQTDAEGQPVNSVGVFEDVYPVTRELYLGAVVDRSSRKVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQ
AREVAFKLGLEGKQINDFVKTMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQEN
AKELKASEHELNYVALKGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVIEAFKLILDDENVKAVLINIF
GGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAKILADSGLKLIPADGLADAADKVVKSLG
>Mature_387_residues
MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGVKVVKSSQEAREVAESLIGKN
LVTFQTDAEGQPVNSVGVFEDVYPVTRELYLGAVVDRSSRKVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQ
AREVAFKLGLEGKQINDFVKTMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQEN
AKELKASEHELNYVALKGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVIEAFKLILDDENVKAVLINIF
GGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAKILADSGLKLIPADGLADAADKVVKSLG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=47.5703324808184, Blast_Score=355, Evalue=3e-98,
Organism=Homo sapiens, GI157779135, Length=384, Percent_Identity=44.7916666666667, Blast_Score=311, Evalue=5e-85,
Organism=Homo sapiens, GI294862256, Length=364, Percent_Identity=45.0549450549451, Blast_Score=298, Evalue=7e-81,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=62.9533678756477, Blast_Score=473, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI17567829, Length=393, Percent_Identity=45.8015267175573, Blast_Score=330, Evalue=7e-91,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=44.0506329113924, Blast_Score=321, Evalue=4e-88,
Organism=Saccharomyces cerevisiae, GI6321683, Length=394, Percent_Identity=44.1624365482233, Blast_Score=330, Evalue=2e-91,
Organism=Drosophila melanogaster, GI161078106, Length=390, Percent_Identity=46.1538461538462, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24645208, Length=390, Percent_Identity=46.1538461538462, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI281361397, Length=391, Percent_Identity=46.2915601023018, Blast_Score=315, Evalue=5e-86,
Organism=Drosophila melanogaster, GI281361395, Length=391, Percent_Identity=46.2915601023018, Blast_Score=315, Evalue=5e-86,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=42.3857868020305, Blast_Score=292, Evalue=2e-79,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41527; Mature: 41527

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCEEECCEEECCCCHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVVKSSQEAREVAESLIGKNLVTFQTDAEGQPVNSVGVFEDVYPVTRELYLGAVVDRSSR
EEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCC
KVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQAREVAFKLGLEGKQINDFVK
EEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHHH
TMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQEN
HHHHHHHHHHEECEEEEEECEEEEECCCCEEEECCEEECCCCCHHCCCEEEEECCCCHHH
AKELKASEHELNYVALKGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVI
HHHHHCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
EAFKLILDDENVKAVLINIFGGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAK
HHHHHHHCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHH
ILADSGLKLIPADGLADAADKVVKSLG
EEECCCCEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCEEECCEEECCCCHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVVKSSQEAREVAESLIGKNLVTFQTDAEGQPVNSVGVFEDVYPVTRELYLGAVVDRSSR
EEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCC
KVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQAREVAFKLGLEGKQINDFVK
EEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHHH
TMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQEN
HHHHHHHHHHEECEEEEEECEEEEECCCCEEEECCEEECCCCCHHCCCEEEEECCCCHHH
AKELKASEHELNYVALKGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVI
HHHHHCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
EAFKLILDDENVKAVLINIFGGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAK
HHHHHHHCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHH
ILADSGLKLIPADGLADAADKVVKSLG
EEECCCCEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA