Click here to switch to the map view.

The map label for this gene is preA [H]

Identifier: 134300043

GI number: 134300043

Start: 2404484

End: 2405254

Strand: Reverse

Name: preA [H]

Synonym: Dred_2199

Alternate gene names: 134300043

Gene position: 2405254-2404484 (Counterclockwise)

Preceding gene: 134300044

Following gene: 134300042

Centisome position: 66.66

GC content: 40.21

Gene sequence:

>771_bases
ATGTTAGGCGATTTATTTGCGGGTTTTTGGGAAGATATAAAAACTATTCATAATAATATTAAAACACAATTGTTTGTAAA
AGTTGGTCATGTTGGGGAATACGCACATTTGGAATTCTCTCCCCAAGATAATTTTATCCGCCCAGCGATGGTGCTTATTG
TGGCAAGATTATACAACTGCAGGTCTCCTAGGGTATTGTCCCTTGGTGCAATTGTGCAGTTTATTTTTATGGCTTCCTGT
ATTCATAAAAAAATTCCAGATGCTGCTGTGCCAAATCATACAGTTGATCCTAGGGACGGTACCCAGTTTCCTGTTCTAGT
AGGAGATTACCTTTATGGGAAATTCTTTACGAACCTATGTAATTCAGGCCTACTATGTTATCTTCGTCCCCTAGCTGAGA
TCATTGGTGCCATTCATGAGGGCGGCATATTGAAGATAAATAAAGCTGCACAATTAAAAGACGATAACCAATTAATGAAT
GAAATTATTCGTCTGGAAGTGGCAGAGCTCATGGCGGGAGCTGCAAGTCTGGCAGGAGATGTAGCAGGGGCGCCACAGAA
AGACCAACAGCTTCTTCATGAATTTGGCCTTAATTTAGGGATGCTCTATGGCTTAAACCAAGCAAATTGTATTGATGGAC
AGGCCCTTACGTATTATAAACAGGCCAAAATGGTGTTGGAGAAACTACCAAGCCATCTTGAAAAAACCATGTTGGAACAA
CTCCTTCATAGTTTATACTTGAACCAAGACATCATCCGTAAGGTTGTCTAA

Upstream 100 bases:

>100_bases
GTCAGTTTTTTTATGTCCTTTTTCCAAATACTTAAAAGAGGAAATCTCCCTTAATTCACGAAGTAATAATAAGTTAACCG
CCAAAAGGGGGCTTTTGTTA

Downstream 100 bases:

>100_bases
AAAGAAGGGAGAACTACCGCAGTGCAACAGTTTAATGGAAAAAATAAAGAAGAATTTGTGCATGGGGTATTTTCTACCAT
TGCCCACCGCTATGATCTAA

Product: hypothetical protein

Products: trans-polyisoprenyln-PP; pyrophosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MLGDLFAGFWEDIKTIHNNIKTQLFVKVGHVGEYAHLEFSPQDNFIRPAMVLIVARLYNCRSPRVLSLGAIVQFIFMASC
IHKKIPDAAVPNHTVDPRDGTQFPVLVGDYLYGKFFTNLCNSGLLCYLRPLAEIIGAIHEGGILKINKAAQLKDDNQLMN
EIIRLEVAELMAGAASLAGDVAGAPQKDQQLLHEFGLNLGMLYGLNQANCIDGQALTYYKQAKMVLEKLPSHLEKTMLEQ
LLHSLYLNQDIIRKVV

Sequences:

>Translated_256_residues
MLGDLFAGFWEDIKTIHNNIKTQLFVKVGHVGEYAHLEFSPQDNFIRPAMVLIVARLYNCRSPRVLSLGAIVQFIFMASC
IHKKIPDAAVPNHTVDPRDGTQFPVLVGDYLYGKFFTNLCNSGLLCYLRPLAEIIGAIHEGGILKINKAAQLKDDNQLMN
EIIRLEVAELMAGAASLAGDVAGAPQKDQQLLHEFGLNLGMLYGLNQANCIDGQALTYYKQAKMVLEKLPSHLEKTMLEQ
LLHSLYLNQDIIRKVV
>Mature_256_residues
MLGDLFAGFWEDIKTIHNNIKTQLFVKVGHVGEYAHLEFSPQDNFIRPAMVLIVARLYNCRSPRVLSLGAIVQFIFMASC
IHKKIPDAAVPNHTVDPRDGTQFPVLVGDYLYGKFFTNLCNSGLLCYLRPLAEIIGAIHEGGILKINKAAQLKDDNQLMN
EIIRLEVAELMAGAASLAGDVAGAPQKDQQLLHEFGLNLGMLYGLNQANCIDGQALTYYKQAKMVLEKLPSHLEKTMLEQ
LLHSLYLNQDIIRKVV

Specific function: Possible role in synthesis of the nonaprenyl side chain of plastoquinone or in synthesis of other prenyl chains such as undekaprenyl pyrophosphate [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789578, Length=198, Percent_Identity=23.7373737373737, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR014120
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 28534; Mature: 28534

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGDLFAGFWEDIKTIHNNIKTQLFVKVGHVGEYAHLEFSPQDNFIRPAMVLIVARLYNC
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCC
RSPRVLSLGAIVQFIFMASCIHKKIPDAAVPNHTVDPRDGTQFPVLVGDYLYGKFFTNLC
CCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NSGLLCYLRPLAEIIGAIHEGGILKINKAAQLKDDNQLMNEIIRLEVAELMAGAASLAGD
CCCHHHHHHHHHHHHHHHHCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGAPQKDQQLLHEFGLNLGMLYGLNQANCIDGQALTYYKQAKMVLEKLPSHLEKTMLEQ
CCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLHSLYLNQDIIRKVV
HHHHHHHCHHHHHHCC
>Mature Secondary Structure
MLGDLFAGFWEDIKTIHNNIKTQLFVKVGHVGEYAHLEFSPQDNFIRPAMVLIVARLYNC
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCC
RSPRVLSLGAIVQFIFMASCIHKKIPDAAVPNHTVDPRDGTQFPVLVGDYLYGKFFTNLC
CCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NSGLLCYLRPLAEIIGAIHEGGILKINKAAQLKDDNQLMNEIIRLEVAELMAGAASLAGD
CCCHHHHHHHHHHHHHHHHCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGAPQKDQQLLHEFGLNLGMLYGLNQANCIDGQALTYYKQAKMVLEKLPSHLEKTMLEQ
CCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLHSLYLNQDIIRKVV
HHHHHHHCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trans-polyisoprenyln-PP; Delta3-isopentenyl-PP [C]

Specific reaction: trans-polyisoprenyln-PP + Delta3-isopentenyl-PP = trans-polyisoprenyln-PP + pyrophosphate [C]

General reaction: Transferring alkyl or aryl groups, other than methyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]