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The map label for this gene is speH [H]

Identifier: 134300044

GI number: 134300044

Start: 2405428

End: 2405811

Strand: Reverse

Name: speH [H]

Synonym: Dred_2200

Alternate gene names: 134300044

Gene position: 2405811-2405428 (Counterclockwise)

Preceding gene: 134300045

Following gene: 134300043

Centisome position: 66.68

GC content: 45.57

Gene sequence:

>384_bases
ATGAAACCTTTGGGCCGCCATGTCTTGGCTGAAATCTATGGCTGTGATTTTGAAATCCTCAATGATGTTAAGAAGGTTGA
GGAAATTATGGTTAACGCAGCACTGGAATCGGGGGCTGAGGTCCGCGAATATGTTTTTCACAAATTTAGTCCACAGGGAG
TTAGTGGTGTAGTAGTAATTAGTGAAAGCCACCTGGCTATTCATACCTGGCCTGAATTAGGTTACGCTGCGGTTGATGTC
TTTACCTGTGGTGATTCAGTGAATCCCTGGGATGCATGCAACTTCTTAACCAGAGAATTTGGTGCAAAGGATATGTCTGC
TCAGGAGACTAAGAGAGGAATCCTGCCTGGTATGGCGCCGCATTTGGTGGCTGCAAATTCATAG

Upstream 100 bases:

>100_bases
TAAAATTGACTTTGGTTGGAATTGACCAGCCCGAAAACTTAGTAATTTGGGCTGGTTAGTTCCAACATTTTATTAAGTGA
AATGGAGGAGGATAACTATA

Downstream 100 bases:

>100_bases
GAGGGATATTTATTAGTACCAAGAGTAGCACGACCTGACGAGCCTTGCACATCGTGATGATGTAGCGAGGCTCGTCAGTT
TTTTTATGTCCTTTTTCCAA

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MKPLGRHVLAEIYGCDFEILNDVKKVEEIMVNAALESGAEVREYVFHKFSPQGVSGVVVISESHLAIHTWPELGYAAVDV
FTCGDSVNPWDACNFLTREFGAKDMSAQETKRGILPGMAPHLVAANS

Sequences:

>Translated_127_residues
MKPLGRHVLAEIYGCDFEILNDVKKVEEIMVNAALESGAEVREYVFHKFSPQGVSGVVVISESHLAIHTWPELGYAAVDV
FTCGDSVNPWDACNFLTREFGAKDMSAQETKRGILPGMAPHLVAANS
>Mature_127_residues
MKPLGRHVLAEIYGCDFEILNDVKKVEEIMVNAALESGAEVREYVFHKFSPQGVSGVVVISESHLAIHTWPELGYAAVDV
FTCGDSVNPWDACNFLTREFGAKDMSAQETKRGILPGMAPHLVAANS

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 13878; Mature: 13878

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLGRHVLAEIYGCDFEILNDVKKVEEIMVNAALESGAEVREYVFHKFSPQGVSGVVVI
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEE
SESHLAIHTWPELGYAAVDVFTCGDSVNPWDACNFLTREFGAKDMSAQETKRGILPGMAP
ECCCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCC
HLVAANS
CEEECCC
>Mature Secondary Structure
MKPLGRHVLAEIYGCDFEILNDVKKVEEIMVNAALESGAEVREYVFHKFSPQGVSGVVVI
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEE
SESHLAIHTWPELGYAAVDVFTCGDSVNPWDACNFLTREFGAKDMSAQETKRGILPGMAP
ECCCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCC
HLVAANS
CEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA