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The map label for this gene is queC

Identifier: 126697220

GI number: 126697220

Start: 1609416

End: 1610090

Strand: Direct

Name: queC

Synonym: P9301_18821

Alternate gene names: 126697220

Gene position: 1609416-1610090 (Clockwise)

Preceding gene: 126697219

Following gene: 126697221

Centisome position: 98.02

GC content: 30.67

Gene sequence:

>675_bases
ATGAATCTTAAAAATAAATCGATAGTAGTTTTATTATCTGGAGGTTTAGATTCTTCTACAGTTACTGGTATCGCAAAAAA
ATCCGAAGCTAAAATTTTTGGCCTTTCATTTGACTACGGTCAACGTCATAAAAAAGAATTAAATTCTGCATCAATAATTG
CAAAACACTTTGATATCGAAGAATTTAAAATCATTAAGCTTGACTTATCTTTATGGGGAGGCTCGTCATTGACTGATTCT
CAAAAAAATATTCCGATAGAAGGAGTACAAGCTAATAAAATTCCTAATACTTATGTTCCCGGAAGAAATACTATATTTAT
TTCCGTTGCACTAAGTTATGCCGAAGCAATAGATGCTGATTTTATAGGATTAGGAGTTAATGCACTTGATTATTCAGGTT
ATCCAGATTGCAGACCTGACTACATTAAAAAATTTCAAGAATTAGCAGATTTAGCCAATAAAAGAGGAAGAGAAAATAAT
CCAATAAAACTTTGGACACCACTATTAGATTTAAATAAAGAGGAAATTATTAAATTAGCTTTTGATAATCATGTCCCTTT
TGATAAAACATGGAGTTGTTATTCGGGTAATTCAAAACCATGCGGTAAGTGTGATAGCTGCAGAATTAGAAATGCCGCTT
ATGAAAAATGGCTTAATAACAAAAATAAAAAATGA

Upstream 100 bases:

>100_bases
TGCGAATGGTTTTTCTCTTGCTATTGATTTCGTAAAAAATAACCCCGATTGGAAATTGAGCCTTCAAACTCACAAATACT
TAAAAATTAATTGAAATCAT

Downstream 100 bases:

>100_bases
AAATAAAAAAATTAATTCTAGAAAAATGGATAGATCCAGCACTGATTACGCATCATCTAACAAAAAAATTCGGAGATAAA
GGGTTAGCTTGGCTAGACAG

Product: ATPase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MNLKNKSIVVLLSGGLDSSTVTGIAKKSEAKIFGLSFDYGQRHKKELNSASIIAKHFDIEEFKIIKLDLSLWGGSSLTDS
QKNIPIEGVQANKIPNTYVPGRNTIFISVALSYAEAIDADFIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENN
PIKLWTPLLDLNKEEIIKLAFDNHVPFDKTWSCYSGNSKPCGKCDSCRIRNAAYEKWLNNKNKK

Sequences:

>Translated_224_residues
MNLKNKSIVVLLSGGLDSSTVTGIAKKSEAKIFGLSFDYGQRHKKELNSASIIAKHFDIEEFKIIKLDLSLWGGSSLTDS
QKNIPIEGVQANKIPNTYVPGRNTIFISVALSYAEAIDADFIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENN
PIKLWTPLLDLNKEEIIKLAFDNHVPFDKTWSCYSGNSKPCGKCDSCRIRNAAYEKWLNNKNKK
>Mature_224_residues
MNLKNKSIVVLLSGGLDSSTVTGIAKKSEAKIFGLSFDYGQRHKKELNSASIIAKHFDIEEFKIIKLDLSLWGGSSLTDS
QKNIPIEGVQANKIPNTYVPGRNTIFISVALSYAEAIDADFIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENN
PIKLWTPLLDLNKEEIIKLAFDNHVPFDKTWSCYSGNSKPCGKCDSCRIRNAAYEKWLNNKNKK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=222, Percent_Identity=33.7837837837838, Blast_Score=124, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_PROM0 (A3PFI0)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001092106.1
- ProteinModelPortal:   A3PFI0
- SMR:   A3PFI0
- STRING:   A3PFI0
- GeneID:   4912709
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_18821
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK922250
- BioCyc:   PMAR167546:P9301ORF_1924-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25053; Mature: 25053

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKNKSIVVLLSGGLDSSTVTGIAKKSEAKIFGLSFDYGQRHKKELNSASIIAKHFDIE
CCCCCCEEEEEEECCCCCHHHEHHHCCCCCEEEEEECCCCHHHHHHCCHHHEEHHHCCCC
EFKIIKLDLSLWGGSSLTDSQKNIPIEGVQANKIPNTYVPGRNTIFISVALSYAEAIDAD
CEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHCCC
FIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENNPIKLWTPLLDLNKEEIIKLA
EEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCHHHEEEEE
FDNHVPFDKTWSCYSGNSKPCGKCDSCRIRNAAYEKWLNNKNKK
ECCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNLKNKSIVVLLSGGLDSSTVTGIAKKSEAKIFGLSFDYGQRHKKELNSASIIAKHFDIE
CCCCCCEEEEEEECCCCCHHHEHHHCCCCCEEEEEECCCCHHHHHHCCHHHEEHHHCCCC
EFKIIKLDLSLWGGSSLTDSQKNIPIEGVQANKIPNTYVPGRNTIFISVALSYAEAIDAD
CEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHCCC
FIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENNPIKLWTPLLDLNKEEIIKLA
EEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCHHHEEEEE
FDNHVPFDKTWSCYSGNSKPCGKCDSCRIRNAAYEKWLNNKNKK
ECCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA