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The map label for this gene is trpE2 [H]

Identifier: 126697221

GI number: 126697221

Start: 1610087

End: 1611403

Strand: Direct

Name: trpE2 [H]

Synonym: P9301_18831

Alternate gene names: 126697221

Gene position: 1610087-1611403 (Clockwise)

Preceding gene: 126697220

Following gene: 126697222

Centisome position: 98.06

GC content: 28.78

Gene sequence:

>1317_bases
ATGAAAATAAAAAAATTAATTCTAGAAAAATGGATAGATCCAGCACTGATTACGCATCATCTAACAAAAAAATTCGGAGA
TAAAGGGTTAGCTTGGCTAGACAGTGATGGTAAAGAAAATGGGGAATGGTCAATAATAGGAATAAAACCTAAAAAAATAA
TACAATCAAGAGATATCAATAACTTAGACAAAACTAATAATCCATTTAACAATTTAAAAAATATTGAAAAAGGATTTTGG
ATCGGATGGTTAAGTTATGAAGCTGGAGTTTACATAGAACCCAAAAACCCATGGCGAAAATCTAATATGGCAACTTTATG
GATTGCGTCATATGATCCAATCATTAAATGTAATCTAATAAAAAAAGAAATAATTATCGAAGGCACAAACTCATCTGAAC
TGATGAAATTTAAAAATACAATAGACAATATAAAAAATATTGAAGAAGAAAATATTATTAAAACAAATTTAAATTTTGAT
TTTTCAAAAATAAATTTGGACGAAATGGCTGAAAAATTTCAGAAAAATATTCTAAAATTAAAGAAATTAATTTCTGAAGG
GGATATATTTCAAGCAAACCTAACAACTAAATGCGAGATTGAATCTTCCAAAAATTATAATCCTTTAGATATTTATTTAA
AAATAAGAAGGAAATTAAGAGCTCCATTTGGAGGAATAATAATCAATAATGATAATCATAATGAGGCGGTATTATCTACC
TCCCCAGAAAGATTTATAAAAATAGATAATAAAAGTTTTGTAGAATCAAGACCTATTAAAGGAACTAGATCCAGAGATAA
GGATTTAAATCAAGACGCACTAAATGCTATCGATTTAATAACGAACGAAAAAGATAGAGCCGAAAATATTATGATTGTTG
ACCTAATAAGAAATGATTTAAGTAAAGTTTGCGAAACAGGAAGTATTATGGTGCCAGAAATATTAAAACTTGAAAGTTTC
TTAAAAGTTCATCATCTAACTTCAGTAATCAGAGGCAAATTAAAAAAAAACAAGAACTGGATTGATTTACTAAAAGCTTG
TTGGCCAGGGGGCTCAATAACTGGAGCACCTAAATTAAGATCATGCCAGAGACTTTTTGAATTAGAAGAATATGAACGCG
GACCATACTGTGGCTCGTTTTTGAAGCTTGACTGGAATGGAGAGTTTGACAGCAATATACTAATAAGATCATTTTTAATT
AAAGACAAAAAAATCAGTATATATGCTGGTTGCGGAATAGTTATTGACTCAAACCTTGAAGAGGAAACTAATGAACTAAA
GTGGAAACTTTTACCGTTAATTGATTCACTAAAATGA

Upstream 100 bases:

>100_bases
GGAGTTGTTATTCGGGTAATTCAAAACCATGCGGTAAGTGTGATAGCTGCAGAATTAGAAATGCCGCTTATGAAAAATGG
CTTAATAACAAAAATAAAAA

Downstream 100 bases:

>100_bases
TTGATACATTAGGCTGGTACAAGGATCAATGGTTGGATATTGATAGAATATTTATTGCTGCTAATAATAGAGGATTAAAA
TTTGCTGATGGTATATTTGA

Product: putative p-aminobenzoate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MKIKKLILEKWIDPALITHHLTKKFGDKGLAWLDSDGKENGEWSIIGIKPKKIIQSRDINNLDKTNNPFNNLKNIEKGFW
IGWLSYEAGVYIEPKNPWRKSNMATLWIASYDPIIKCNLIKKEIIIEGTNSSELMKFKNTIDNIKNIEEENIIKTNLNFD
FSKINLDEMAEKFQKNILKLKKLISEGDIFQANLTTKCEIESSKNYNPLDIYLKIRRKLRAPFGGIIINNDNHNEAVLST
SPERFIKIDNKSFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDLSKVCETGSIMVPEILKLESF
LKVHHLTSVIRGKLKKNKNWIDLLKACWPGGSITGAPKLRSCQRLFELEEYERGPYCGSFLKLDWNGEFDSNILIRSFLI
KDKKISIYAGCGIVIDSNLEEETNELKWKLLPLIDSLK

Sequences:

>Translated_438_residues
MKIKKLILEKWIDPALITHHLTKKFGDKGLAWLDSDGKENGEWSIIGIKPKKIIQSRDINNLDKTNNPFNNLKNIEKGFW
IGWLSYEAGVYIEPKNPWRKSNMATLWIASYDPIIKCNLIKKEIIIEGTNSSELMKFKNTIDNIKNIEEENIIKTNLNFD
FSKINLDEMAEKFQKNILKLKKLISEGDIFQANLTTKCEIESSKNYNPLDIYLKIRRKLRAPFGGIIINNDNHNEAVLST
SPERFIKIDNKSFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDLSKVCETGSIMVPEILKLESF
LKVHHLTSVIRGKLKKNKNWIDLLKACWPGGSITGAPKLRSCQRLFELEEYERGPYCGSFLKLDWNGEFDSNILIRSFLI
KDKKISIYAGCGIVIDSNLEEETNELKWKLLPLIDSLK
>Mature_438_residues
MKIKKLILEKWIDPALITHHLTKKFGDKGLAWLDSDGKENGEWSIIGIKPKKIIQSRDINNLDKTNNPFNNLKNIEKGFW
IGWLSYEAGVYIEPKNPWRKSNMATLWIASYDPIIKCNLIKKEIIIEGTNSSELMKFKNTIDNIKNIEEENIIKTNLNFD
FSKINLDEMAEKFQKNILKLKKLISEGDIFQANLTTKCEIESSKNYNPLDIYLKIRRKLRAPFGGIIINNDNHNEAVLST
SPERFIKIDNKSFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDLSKVCETGSIMVPEILKLESF
LKVHHLTSVIRGKLKKNKNWIDLLKACWPGGSITGAPKLRSCQRLFELEEYERGPYCGSFLKLDWNGEFDSNILIRSFLI
KDKKISIYAGCGIVIDSNLEEETNELKWKLLPLIDSLK

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=264, Percent_Identity=39.7727272727273, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1787518, Length=268, Percent_Identity=31.7164179104478, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI87082077, Length=247, Percent_Identity=27.5303643724696, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786809, Length=196, Percent_Identity=27.0408163265306, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=442, Percent_Identity=28.5067873303167, Blast_Score=160, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6324361, Length=283, Percent_Identity=30.3886925795053, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR010118 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 50456; Mature: 50456

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKKLILEKWIDPALITHHLTKKFGDKGLAWLDSDGKENGEWSIIGIKPKKIIQSRDIN
CCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCHHHHHHHCCCC
NLDKTNNPFNNLKNIEKGFWIGWLSYEAGVYIEPKNPWRKSNMATLWIASYDPIIKCNLI
CCCCCCCCHHHHHHHCCCEEEEEEEECCCEEECCCCCCCCCCEEEEEEECCCCEEEEEEE
KKEIIIEGTNSSELMKFKNTIDNIKNIEEENIIKTNLNFDFSKINLDEMAEKFQKNILKL
EEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHH
KKLISEGDIFQANLTTKCEIESSKNYNPLDIYLKIRRKLRAPFGGIIINNDNHNEAVLST
HHHHCCCCEEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEC
SPERFIKIDNKSFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDL
CCCCEEEECCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCEEEHHHHHHHH
SKVCETGSIMVPEILKLESFLKVHHLTSVIRGKLKKNKNWIDLLKACWPGGSITGAPKLR
HHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHH
SCQRLFELEEYERGPYCGSFLKLDWNGEFDSNILIRSFLIKDKKISIYAGCGIVIDSNLE
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEEECCCEEECCCCC
EETNELKWKLLPLIDSLK
HHHHHHHEEEEHHHHCCC
>Mature Secondary Structure
MKIKKLILEKWIDPALITHHLTKKFGDKGLAWLDSDGKENGEWSIIGIKPKKIIQSRDIN
CCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCHHHHHHHCCCC
NLDKTNNPFNNLKNIEKGFWIGWLSYEAGVYIEPKNPWRKSNMATLWIASYDPIIKCNLI
CCCCCCCCHHHHHHHCCCEEEEEEEECCCEEECCCCCCCCCCEEEEEEECCCCEEEEEEE
KKEIIIEGTNSSELMKFKNTIDNIKNIEEENIIKTNLNFDFSKINLDEMAEKFQKNILKL
EEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHH
KKLISEGDIFQANLTTKCEIESSKNYNPLDIYLKIRRKLRAPFGGIIINNDNHNEAVLST
HHHHCCCCEEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEC
SPERFIKIDNKSFVESRPIKGTRSRDKDLNQDALNAIDLITNEKDRAENIMIVDLIRNDL
CCCCEEEECCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCEEEHHHHHHHH
SKVCETGSIMVPEILKLESFLKVHHLTSVIRGKLKKNKNWIDLLKACWPGGSITGAPKLR
HHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHH
SCQRLFELEEYERGPYCGSFLKLDWNGEFDSNILIRSFLIKDKKISIYAGCGIVIDSNLE
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEEECCCEEECCCCC
EETNELKWKLLPLIDSLK
HHHHHHHEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]