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The map label for this gene is ttcA [H]

Identifier: 126701229

GI number: 126701229

Start: 4209384

End: 4210118

Strand: Direct

Name: ttcA [H]

Synonym: CD3602

Alternate gene names: 126701229

Gene position: 4209384-4210118 (Clockwise)

Preceding gene: 126701222

Following gene: 126701239

Centisome position: 98.12

GC content: 28.44

Gene sequence:

>735_bases
ATGTCTATACAAAAACTTCTAAGTAAAGCTCGTAAGGCTATACAAGATTTTGATATGATACAAGAAAATGATAAAATTGC
AGTTGGACTTTCTGGTGGAAAAGATAGTTTAACTTTACTTCATATACTTAAAAGTTATCAAAGATTTTCTCCACAAAACT
TTGAATTGATAGCCATAACATTAAATACTGGAGGTGTTGATAATTCTCCACTAGATAAATTGTGTAAAGAAATAAATGTT
CCTTTTTATGAATTTCAAACTGACATAAAAGAAATTGTATTTGATATAAGACAAGAAAAGAATCCTTGTGCATTATGTGC
TAATTTAAGAAGAGGTGCTTTGAACGATAATGCTAAAAAACTTGGATGTAATAAAGTAGCTCTTGGTCATCATAAAGATG
ATGCAATTGAGACATTTTTAATGTCTATGTTTTATGAGGGTAGAGTAAATTGTTTTTCCCCAAAGACATACCTAGACAGA
CAGGATTTAACAGTTATAAGACCTATGGTTTACATAGAAGAGTATATGACTAAGAAAATTTCAAAAGATTCTAACTATCC
TATTATCACAAATCCCTGCCCTGCAAATGGTCATACTAGGAGAGAGTACATAAAAAATCTTATTGCTAATTTAAATAAAG
AGATGCCTGATTTTAAAAGAAATGTATTTGGTGCTTTAAATAATTCTGAGAAATTGTTTATATGGGATAAAGAGAAGATA
AAAAATTTTAAATAA

Upstream 100 bases:

>100_bases
TGTTTGCTATAATGTTAATTTTAGAGTATAAGACTTAAGTATTTTATAAGTAAATCTTAAATAAATCTTAAATTTAATAT
TTTTAAAGGATGGTGATAAA

Downstream 100 bases:

>100_bases
TAATTAAAATTTTTAAATAAAAAAGCAAGATTGTATTAATTGTAAATAATCTTTATATAATCTACACAATCTTACTTTTT
TATTTATTATATGTTATTAT

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILKSYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINV
PFYEFQTDIKEIVFDIRQEKNPCALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDFKRNVFGALNNSEKLFIWDKEKI
KNFK

Sequences:

>Translated_244_residues
MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILKSYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINV
PFYEFQTDIKEIVFDIRQEKNPCALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDFKRNVFGALNNSEKLFIWDKEKI
KNFK
>Mature_243_residues
SIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILKSYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVP
FYEFQTDIKEIVFDIRQEKNPCALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDRQ
DLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDFKRNVFGALNNSEKLFIWDKEKIK
NFK

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=229, Percent_Identity=35.3711790393013, Blast_Score=146, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI193211090, Length=230, Percent_Identity=32.6086956521739, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17540090, Length=238, Percent_Identity=24.7899159663866, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24651972, Length=220, Percent_Identity=26.8181818181818, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 28080; Mature: 27949

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILKSYQRFSPQNFELIAIT
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEE
LNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNPCALCANLRRGALNDNAKK
EECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHH
LGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDRQDLTVIRPMVYIEEYMTKKI
CCCCCEECCCCCHHHHHHHHHHHHHCCCCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHH
SKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDFKRNVFGALNNSEKLFIWDKEKI
CCCCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEHHHC
KNFK
CCCC
>Mature Secondary Structure 
SIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILKSYQRFSPQNFELIAIT
CHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEE
LNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNPCALCANLRRGALNDNAKK
EECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHH
LGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDRQDLTVIRPMVYIEEYMTKKI
CCCCCEECCCCCHHHHHHHHHHHHHCCCCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHH
SKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDFKRNVFGALNNSEKLFIWDKEKI
CCCCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEHHHC
KNFK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA