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The map label for this gene is 126701222

Identifier: 126701222

GI number: 126701222

Start: 4201307

End: 4202536

Strand: Direct

Name: 126701222

Synonym: CD3595

Alternate gene names: NA

Gene position: 4201307-4202536 (Clockwise)

Preceding gene: 126701210

Following gene: 126701229

Centisome position: 97.93

GC content: 31.79

Gene sequence:

>1230_bases
ATGAATTTAAATAGAAATTTAGAAAAATACGCTGAATTAGCAATAAAAGTTGGAGTTAACATACAGCCAGGTCAAATTCT
ACTTATAAAGTCACCAATAGAATGTGCTGATTTTGCAAGAAATGCACTTAAAGAAGCATATAAATGTGGTGCTAAAAATG
TTTATATAGAGTGGTCTGATGAAGAAAGTACTCTTATTAAATACTTATATGCTCCAGATGAAGCATTTCATGAGTTCCCC
AAATGGACAGCAGAACAATATGTAGATATAGCAAAAGAAGGTGGGGCATTTTTATCAGTCTATGCCCAAAATCCAGATTT
ATTAAAAGATGTTGACCCTGAAAGAGTTGCAAATTTTCAGAAGGCATCTGGAAAAGCTTTAAAAGAATGGCGTTCTTACA
CTCTAACTGATAAATGTAAATGGAGTATAGTCTCTGTGCCAACAAAAGATTGGGCAAAAAAAGTGTTTCCAAATTTATCA
GAAGATAAAGCAATAGAAAAACTGTGGGATGCTATATTTAAATGTTCAAGAGTAGATGGTCAGGACCCTATAAAAGCATG
GGAAGAACATAATGAAAATCTTAAATCTAAAATGGACTTTCTAAATAAAAATAACTTTAAAACTTTAAAATATAAATCCT
CAAAAACTGATTTGACTCTAGACTTGCCAAAGGGTCATGTTTGGCTAAGTGGAGCATCCAAAGACCCTAATGGAATAAGT
TTTAATCCGAATATTCCAACTGAAGAGATTTTTGGAATGCCACATAAGTTTAAAGTAAATGGAACTGTTTATAGTACAAA
ACCTCTTGTTTATGGTGGAAACATAATTGACAATTTCTTCTTAACATTTAAAGATGGTAAAATAATAGATTTCTCTGCTG
AAAAGGGACTAGATACACTAGAAAAACTTATTGAAACGGATGAAGGCTCTCATTATTTAGGAGAAGTCGCTCTTGTTCCA
TACAACTCACCAATATCCAATACGGATATAATTTTTTATAATACTCTATATGATGAAAATGCTTCTTGCCACTTTGCAAT
TGGTTCTGCTTATAAGACTTGTCTGGAAGGTGGAAACAATTTAAAAGATGAAGAATTGGATGAACATGGTGTAAATGATA
GTTTAACACATGTAGATTTTATGATTGGTTCTGCTGATATGGATATTATTGGTGAGACTTATGATGGAAAGCAAATACAG
ATTTTTAAAAATGGTAATTGGGCTTTTTAA

Upstream 100 bases:

>100_bases
GTAAAGTTATAATATTTTATAAGTTGTTCAATATTAAAAACATAAGTAATGTTATAATACTTTATAAGTTATTCAATATT
AAAAATATAGGAGGATAAAT

Downstream 100 bases:

>100_bases
CATATGATTTTAACTAAAAAGGGCTGATGGAAGTTATACCAGACTTCCCAGCCCTTTTTAATGTTGATGATAAATATTTT
TTATATTAATTAATCTCATT

Product: aminopeptidase

Products: NA

Alternate protein names: Aminopeptidase II; AP-II [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALKEAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFP
KWTAEQYVDIAKEGGAFLSVYAQNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDLTLDLPKGHVWLSGASKDPNGIS
FNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNIIDNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVP
YNSPISNTDIIFYNTLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGETYDGKQIQ
IFKNGNWAF

Sequences:

>Translated_409_residues
MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALKEAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFP
KWTAEQYVDIAKEGGAFLSVYAQNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDLTLDLPKGHVWLSGASKDPNGIS
FNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNIIDNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVP
YNSPISNTDIIFYNTLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGETYDGKQIQ
IFKNGNWAF
>Mature_409_residues
MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALKEAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFP
KWTAEQYVDIAKEGGAFLSVYAQNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDLTLDLPKGHVWLSGASKDPNGIS
FNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNIIDNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVP
YNSPISNTDIIFYNTLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGETYDGKQIQ
IFKNGNWAF

Specific function: Broad specificity metal-dependent exopeptidase, releasing all N-terminal amino acids [H]

COG id: COG2309

COG function: function code E; Leucyl aminopeptidase (aminopeptidase T)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M29 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000787 [H]

Pfam domain/function: PF02073 Peptidase_M29 [H]

EC number: NA

Molecular weight: Translated: 46234; Mature: 46234

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALKEAYKCGAKNVYIEWSD
CCCCCCHHHHHHEEEEECCEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECC
EESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYAQNPDLLKDVDPERVANFQ
CCCEEEEEEECCCHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCHHHHHHHH
KASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLSEDKAIEKLWDAIFKCSRVDG
HHCCHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
QDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDLTLDLPKGHVWLSGASKDPNGIS
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCEEEEECCCCCCCCEE
FNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNIIDNFFLTFKDGKIIDFSAEKGLDTL
ECCCCCHHHHHCCCCEEEECCEEEECCCEEECCCEEECEEEEEECCEEEEECHHCCHHHH
EKLIETDEGSHYLGEVALVPYNSPISNTDIIFYNTLYDENASCHFAIGSAYKTCLEGGNN
HHHHCCCCCCEEEEEEEEEECCCCCCCCCEEEEEEEECCCCEEEEEEHHHHHHHHCCCCC
LKDEELDEHGVNDSLTHVDFMIGSADMDIIGETYDGKQIQIFKNGNWAF
CCCHHHHHCCCCCCCEEEEEEECCCCCEEECCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALKEAYKCGAKNVYIEWSD
CCCCCCHHHHHHEEEEECCEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECC
EESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYAQNPDLLKDVDPERVANFQ
CCCEEEEEEECCCHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCHHHHHHHH
KASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLSEDKAIEKLWDAIFKCSRVDG
HHCCHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
QDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDLTLDLPKGHVWLSGASKDPNGIS
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCEEEEECCCCCCCCEE
FNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNIIDNFFLTFKDGKIIDFSAEKGLDTL
ECCCCCHHHHHCCCCEEEECCEEEECCCEEECCCEEECEEEEEECCEEEEECHHCCHHHH
EKLIETDEGSHYLGEVALVPYNSPISNTDIIFYNTLYDENASCHFAIGSAYKTCLEGGNN
HHHHCCCCCCEEEEEEEEEECCCCCCCCCEEEEEEEECCCCEEEEEEHHHHHHHHCCCCC
LKDEELDEHGVNDSLTHVDFMIGSADMDIIGETYDGKQIQIFKNGNWAF
CCCHHHHHCCCCCCCEEEEEEECCCCCEEECCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9362117; 938681 [H]