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The map label for this gene is dapD

Identifier: 126700847

GI number: 126700847

Start: 3776445

End: 3777161

Strand: Direct

Name: dapD

Synonym: CD3227

Alternate gene names: 126700847

Gene position: 3776445-3777161 (Clockwise)

Preceding gene: 126700846

Following gene: 126700849

Centisome position: 88.02

GC content: 33.89

Gene sequence:

>717_bases
ATGGTAAATTTAAACGATGCTTATGAAATAGCAAGGTATATAAAAGAAGTTAAAAAGAAAACACCTGTTAAGGTATATGT
AAATACTAACTCTTTACACTTCCAATCAACTGATAAATTTAAGGTATTTGGAAGTAATGGTTCTTATATATTTGTAGGTG
ACTATGAGGATATAATGGAAGTATTAGATAAACATGGAAATGATATAACAGATACTCATGTAGAATATGATAGAAGAAAT
TCTGCTATTCCTCTAAAAAATACTTTAAGTGAACATGCAAGAATTGAGCCAGGTGCAATAATAAGAGACATGGTTACTAT
AGAAAAAAATGCTGTTGTAATGATGGGAGCTGTTATAAATATAGGAGCTGTTATTGGTGAAGGTTCTATGGTAGATATGA
ATGCTGTTATTGGAGCTAGAGGAACTCTTGGTAAAAATGTTCACTTAGGTGCTGGTGCTGTTGTTGCTGGTGTTTTAGAG
CCACCTTCTGCTACTCCTGTTATAGTTGAAGATGATGTTTTAATAGGAGCTAATGCAGTTATTCTTGAAGGTGTTAGAAT
CGGTAAAGGTGCTGTTGTTGCAGCTGGTGCTGTTGTAACTACTGATGTAGAAGCTGGTGCCGTTGTTGCTGGTTCTCCTG
CTAAAGTTATAAAAATGAAAGATGAAAAAACGGCTGACAAAACTAAGCTTATGGAAGACCTTAGAAATTTAGATTAA

Upstream 100 bases:

>100_bases
AATAAAATAAAATATAAATAATAAGAAGTAAGTATATACTAAAATTGACAAATAAGTATATAATAAAAGAAATATAATGA
AATACAAGGAGAATTAACAA

Downstream 100 bases:

>100_bases
TTAAATAGTACTATGCTATTAATTAAACAATAATATACTAATTTAAAAAATTAATTAAAAAGGTGTCTCTGTGTGAATTT
AATTCACCAGAGGCACCCTC

Product: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-acetyltransferase; THP acetyltransferase; Tetrahydropicolinate acetylase

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFGSNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRN
SAIPLKNTLSEHARIEPGAIIRDMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIKMKDEKTADKTKLMEDLRNLD

Sequences:

>Translated_238_residues
MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFGSNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRN
SAIPLKNTLSEHARIEPGAIIRDMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIKMKDEKTADKTKLMEDLRNLD
>Mature_238_residues
MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFGSNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRN
SAIPLKNTLSEHARIEPGAIIRDMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIKMKDEKTADKTKLMEDLRNLD

Specific function: Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. DapH subfamily

Homologues:

Organism=Escherichia coli, GI1786362, Length=175, Percent_Identity=36, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322243, Length=168, Percent_Identity=30.952380952381, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPH_CLOD6 (Q17ZX2)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001089744.1
- ProteinModelPortal:   Q17ZX2
- SMR:   Q17ZX2
- STRING:   Q17ZX2
- GeneID:   4915234
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD3227
- NMPDR:   fig|1496.1.peg.858
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   KNAVIMM
- ProtClustDB:   CLSK2535543
- HAMAP:   MF_01691
- InterPro:   IPR013710
- InterPro:   IPR018357
- InterPro:   IPR019873
- InterPro:   IPR011004
- TIGRFAMs:   TIGR03532

Pfam domain/function: PF08503 DapD_N; SSF51161 Trimer_LpxA_like

EC number: =2.3.1.89

Molecular weight: Translated: 25330; Mature: 25330

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFGSNGSYIFVGDYEDIME
CCCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCEEEEECCCCEEEEECHHHHHH
VLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIRDMVTIEKNAVVMMGAVIN
HHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHEEECCCCEEEEEHHHH
IGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLEPPSATPVIVEDDVLIGANAV
HEEEECCCCEEEEHEEEECCCCCCCEEEECCCCEEEEEECCCCCCCEEEECCEEECCCEE
ILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIKMKDEKTADKTKLMEDLRNLD
EEECEEECCCEEEECCEEEEECCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFGSNGSYIFVGDYEDIME
CCCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCEEEEECCCCEEEEECHHHHHH
VLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIRDMVTIEKNAVVMMGAVIN
HHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHEEECCCCEEEEEHHHH
IGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLEPPSATPVIVEDDVLIGANAV
HEEEECCCCEEEEHEEEECCCCCCCEEEECCCCEEEEEECCCCCCCEEEECCEEECCCEE
ILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIKMKDEKTADKTKLMEDLRNLD
EEECEEECCCEEEECCEEEEECCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA