Click here to switch to the map view.

The map label for this gene is dapB1 [H]

Identifier: 126700846

GI number: 126700846

Start: 3775472

End: 3776221

Strand: Direct

Name: dapB1 [H]

Synonym: CD3226

Alternate gene names: 126700846

Gene position: 3775472-3776221 (Clockwise)

Preceding gene: 126700845

Following gene: 126700847

Centisome position: 88.0

GC content: 33.6

Gene sequence:

>750_bases
ATGTTAAAAGTTATAGCAACTGGTTATGATGGAAAAATGGGTAAGATTTTAGCCGATACTATAAGAGAAGATAATGAATT
AGAATTGGTTTGTGTTGCAGCTAGAGGTCTGGATAGCTATGAAGGCGACCTTAAAATTTATGAAGATATGAGTACTATAG
TTGAGGAAGCTGATGTAGTTATAGATTTTTCTCATCACTCTAATTTAGATAATATCTTATCTTACGTTTTAAAGACTAAA
ACACCTTTAGTAATTGCTACTACTGGATATAATGATGACGAAATGAACAAAATACGTGAAGCGGCTAAAGTTATTCCTGT
ATTCCAATCATATAATATGTCTCTTGGTGTAAATGTATTAGTAAAATTGGTTAAAGATGCAGCTAAATTACTAGAAGGAT
TTGATATAGAAATAATAGAAAAACATCACAACAGAAAAGTAGATGCCCCAAGTGGCACAGCTGTTATGATTGCTAACGCT
ATAAAAGAGGTTTTGCCAAACGTTGAAAATAATTATGGTAGATATGGTCGTAGTGCAAAAAGACAACCAAATGAAGTTGG
TATTCATGCTATAAGAGGTGGAAATATTGTTGGCGAACATGATGCTCTATTTGCTGGAGACAATGAGGTTCTTACAATAA
GCCATCAAGCTCAATCTCGTGGTATCTTTGCAAGTGGTTCTATAGCTGCTGCCAAATACTTAGTTAAGCAAAAACCAGGA
TTTTATAATATGGACAGCATGTTGGGATAA

Upstream 100 bases:

>100_bases
ATTAGTTAACTTTGGACTAAAAGTTAATGCATAGTAAAGATTAATGCATGGTAAAAAGTAAGTTTGGTCAAAAGTTAGCC
CTTAATCATAGGAGGAAATT

Downstream 100 bases:

>100_bases
TAGTATAAATATAATAATACACAATATAAATTAAACATATGCAATATAGATATAATAATACGCAATACAAATCAAACATA
TATAATAAATTTATTTAATA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDLKIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTK
TPLVIATTGYNDDEMNKIREAAKVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQSRGIFASGSIAAAKYLVKQKPG
FYNMDSMLG

Sequences:

>Translated_249_residues
MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDLKIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTK
TPLVIATTGYNDDEMNKIREAAKVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQSRGIFASGSIAAAKYLVKQKPG
FYNMDSMLG
>Mature_249_residues
MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDLKIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTK
TPLVIATTGYNDDEMNKIREAAKVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQSRGIFASGSIAAAKYLVKQKPG
FYNMDSMLG

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=209, Percent_Identity=37.799043062201, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 27285; Mature: 27285

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDLKIYEDMSTIVEEADVV
CEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEHHHHHHHHHHCCCEE
IDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAAKVIPVFQSYNMSLGVNVL
EEECCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANAIKEVLPNVENNYGRYGRSAK
HHHHHHHHHHHCCCCCEEEEHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
RQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQSRGIFASGSIAAAKYLVKQKPG
CCCCHHCEEEEECCCEECCCCEEEECCCCEEEEEECCCCCCEEECCCHHHHHHHHHCCCC
FYNMDSMLG
CCCHHHHCC
>Mature Secondary Structure
MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDLKIYEDMSTIVEEADVV
CEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEHHHHHHHHHHCCCEE
IDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAAKVIPVFQSYNMSLGVNVL
EEECCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANAIKEVLPNVENNYGRYGRSAK
HHHHHHHHHHHCCCCCEEEEHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
RQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQSRGIFASGSIAAAKYLVKQKPG
CCCCHHCEEEEECCCEECCCCEEEECCCCEEEEEECCCCCCEEECCCHHHHHHHHHCCCC
FYNMDSMLG
CCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]