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The map label for this gene is dapB2 [H]

Identifier: 126700849

GI number: 126700849

Start: 3779042

End: 3779797

Strand: Direct

Name: dapB2 [H]

Synonym: CD3229

Alternate gene names: 126700849

Gene position: 3779042-3779797 (Clockwise)

Preceding gene: 126700847

Following gene: 126700861

Centisome position: 88.08

GC content: 30.82

Gene sequence:

>756_bases
ATGTTGAAAGTTATAATTAGTGGCTATAATGGAACAATGGGAAGAGTTTTAGCAGAATGTGTAAAAAAAGATAATGAATT
AGAGTTGGTTTGTGGTGTAGCTAGGTCTGCTGATGAAAAAGGTCATCATAGTGATACAAAACTTTACAAAACAATGACTG
ATGTAACTGAAAAAACTGATGTAATAATAGACTTTTCACATCATGAGACTTTAGAGCCAATATTGTCATATGCTCTAAAA
AATAATACACCTGTAGTATTAGCTACTACTGGATATGACGAAAATGACTTAAATAAAATAGAAGAAGCATCAAAAAACAT
TCCTATATTATTATCATCAAATACATCTCTTGGAGTAAATATATTAATAAAATTAGTTAAGGACGCTTCAAAGATGTTAG
AAGGTTTTGATATTGAAATCATAGAAAAACATCACAATAGAAAAGAAGATGCCCCTAGTGGAACTGCTACTATGATAGCT
AATGCAATTAGAGAAGTCTTGCCTGAAAGTGAAAATACACATGGTAGATATGGTAGAGATTGTAAAAGAAAACCAAATGA
AATTGGAATACACTCTATAAGAGGTGGCAATATAATCAGCGACCATGATGTTATATTTGCAGGTGATAATGAAGTTCTTA
CATTAAGCCATCATTCTCAATCTGATGAAGTATTTGCAAACGGTTCTATAGTTGCAGCTAAATTTTTAATTGGTAAGCAA
TCTGGACTTTATAAAATGTCAGATATACTAGGATAA

Upstream 100 bases:

>100_bases
AAGCTTATTATCACTAATATTATTTTATATAAATTATATTAGTGATAAAATAAACTTATAGAAATATAACAAATTTTTAT
TAATTTCATAGGAGGAATTT

Downstream 100 bases:

>100_bases
GTTTTGTACATAATAAATCTCAATCTATTTAGGTATTCATATTCATCAATTTGAATATCTAATTGATTGAGATTTCTATT
CTAAAAGTTTATAAATTTTA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHSDTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALK
NNTPVVLATTGYDENDLNKIEEASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHHSQSDEVFANGSIVAAKFLIGKQ
SGLYKMSDILG

Sequences:

>Translated_251_residues
MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHSDTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALK
NNTPVVLATTGYDENDLNKIEEASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHHSQSDEVFANGSIVAAKFLIGKQ
SGLYKMSDILG
>Mature_251_residues
MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHSDTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALK
NNTPVVLATTGYDENDLNKIEEASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHHSQSDEVFANGSIVAAKFLIGKQ
SGLYKMSDILG

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=263, Percent_Identity=32.6996197718631, Blast_Score=138, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 27555; Mature: 27555

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHSDTKLYKTMTDVTEKTD
CEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECHHCCCCCCCCCHHHHHHHHHHHHCCCC
VIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEEASKNIPILLSSNTSLGVN
EEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCHHH
ILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIANAIREVLPESENTHGRYGRD
HHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCH
CKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHHSQSDEVFANGSIVAAKFLIGKQ
HHCCCCCCCEEEECCCCEECCCCEEEECCCCEEEEECCCCCCCEEECCCEEEEEEECCCC
SGLYKMSDILG
CCCCHHHHHCC
>Mature Secondary Structure
MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHSDTKLYKTMTDVTEKTD
CEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECHHCCCCCCCCCHHHHHHHHHHHHCCCC
VIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEEASKNIPILLSSNTSLGVN
EEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCHHH
ILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIANAIREVLPESENTHGRYGRD
HHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCH
CKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHHSQSDEVFANGSIVAAKFLIGKQ
HHCCCCCCCEEEECCCCEECCCCEEEECCCCEEEEECCCCCCCEEECCCEEEEEEECCCC
SGLYKMSDILG
CCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]