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The map label for this gene is asd [H]

Identifier: 126700844

GI number: 126700844

Start: 3773400

End: 3774401

Strand: Direct

Name: asd [H]

Synonym: CD3224

Alternate gene names: 126700844

Gene position: 3773400-3774401 (Clockwise)

Preceding gene: 126700843

Following gene: 126700845

Centisome position: 87.95

GC content: 32.04

Gene sequence:

>1002_bases
ATGAAAAAAGTAAATGTAGCAATAGTTGGTGCTACTGGAATGGTAGGTAGAACATTTTTAAAAGTATTAGAAGAAAGAAA
TTTTCCAATAGAAAATCTATTTTTATTCTCTTCTTCTAAATCAGCTGGTTCTAAAGTAATGTTTTGTGGTAAAGAATATA
TAGTAGAAGAATTAAAGGAAACTTCATTTACTGATAGAGGCATACAAATAGCATTATTCTCTGCTGGTGGAAGTATTAGT
GAAAAGTATGCTCCAATAGCTGCTTCAAATGGAATCTTAGTAGTAGATAACTCTAGTCAATGGAGAATGAATCCAGATGT
GCCTTTAGTAGTTCCTGAGGTTAATCCAGAAGCCATAAAAAATCATAAGGGTATAATAGCTAATCCTAACTGCTCTACTA
TACAAGCTATGGTTCCCCTTAAAGCTCTTGATGATAAATACAAAATTAAGAGAGTTGTTTACTCTACTTACCAAGCTGTA
TCTGGTTCTGGTGTTAAAGGTGTTGAAGATTTAGAGAAAGGAATGAACGGTAATCCTACTGGATTCTACCCTCATCAAAT
CTCTTACAACTGTCTTCCTCATATAGATTCATTCACTGAAAATGGATACACTAAAGAAGAAATGAAAATGGTAAATGAAA
CTATGAAAATACTTGATAACTACGATTTAAAAATAACTGCAACTACTGTAAGAGTTCCAGTAAAAAATGGTCATAGTGAA
TCTATAAATGTTGAGTTTAACAATCCATTTGAGTTAGATGATTTAGTAAAAACACTTGAAGAAGCTCCAGGTGTTGTAGT
AGTTGATAATCCTGCTAAAAACGAATATCCAACTGCTGTAGAATTTGATGATAGAGATGAAGTATTTGTTGGAAGAATAA
GAAGAGATTTTAGTGTTGATAATGGTGTAAATCTTTGGGTTGTTGCTGATAATATAAGAAAAGGTGCTGCAACTAACGCA
ATTCAAATAGCTGAAATGGCTTTATCATACGATTTAGTATAA

Upstream 100 bases:

>100_bases
TAATATTAAAGTTTTTGAATATATAAAAATATTAACATATCTTACTTGTATAACTAAAATAAAATAATGTTTTAATAATT
TAAAATTGGGGTGAATTTAT

Downstream 100 bases:

>100_bases
TATACAAACTTGTATAAATATATAATTTTGTAAAATATTAATAGTAACTCAAAAACAAGCATTAGAAGTAACTGTAATAT
AAAACACAAAAATAAAAAAG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGSKVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSIS
EKYAPIAASNGILVVDNSSQWRMNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKILDNYDLKITATTVRVPVKNGHSE
SINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEYPTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNA
IQIAEMALSYDLV

Sequences:

>Translated_333_residues
MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGSKVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSIS
EKYAPIAASNGILVVDNSSQWRMNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKILDNYDLKITATTVRVPVKNGHSE
SINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEYPTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNA
IQIAEMALSYDLV
>Mature_333_residues
MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGSKVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSIS
EKYAPIAASNGILVVDNSSQWRMNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKILDNYDLKITATTVRVPVKNGHSE
SINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEYPTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNA
IQIAEMALSYDLV

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=332, Percent_Identity=34.3373493975904, Blast_Score=189, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6320362, Length=391, Percent_Identity=29.4117647058824, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36758; Mature: 36758

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGSKVMFCGKEYIVEELKE
CCEEEEEEEECCCHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCEEEEECHHHHHHHHHH
TSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWRMNPDVPLVVPEVNPEAIK
CCCCCCCEEEEEEECCCCCCCCCCCEEECCCEEEEECCCCEEECCCCCEEEECCCHHHHH
NHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAVSGSGVKGVEDLEKGMNGNPT
CCCCEEECCCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCC
GFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKILDNYDLKITATTVRVPVKNGHSE
CCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCC
SINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEYPTAVEFDDRDEVFVGRIRRDFSVD
EEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCEEEECCCCCHHHHHHHHCCCCC
NGVNLWVVADNIRKGAATNAIQIAEMALSYDLV
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGSKVMFCGKEYIVEELKE
CCEEEEEEEECCCHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCEEEEECHHHHHHHHHH
TSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWRMNPDVPLVVPEVNPEAIK
CCCCCCCEEEEEEECCCCCCCCCCCEEECCCEEEEECCCCEEECCCCCEEEECCCHHHHH
NHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAVSGSGVKGVEDLEKGMNGNPT
CCCCEEECCCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCC
GFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKILDNYDLKITATTVRVPVKNGHSE
CCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCC
SINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEYPTAVEFDDRDEVFVGRIRRDFSVD
EEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCEEEECCCCCHHHHHHHHCCCCC
NGVNLWVVADNIRKGAATNAIQIAEMALSYDLV
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]