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The map label for this gene is srlR [H]

Identifier: 126699728

GI number: 126699728

Start: 2440349

End: 2441113

Strand: Direct

Name: srlR [H]

Synonym: CD2111

Alternate gene names: 126699728

Gene position: 2440349-2441113 (Clockwise)

Preceding gene: 126699726

Following gene: 126699733

Centisome position: 56.88

GC content: 26.8

Gene sequence:

>765_bases
ATGTTTGCAGAAGAAAGAATCCAAGCTATATTAAATATCCTAAAAAAAGAAGGTAGAGTTACTGTCAAAGAGCTCAGTTC
TAAATTTAATGTTACAGAAGATTGTATAAGAAAAGATTTAAAAAATATAGAAAAGATTTCTTCAATAAGAAGAATTTATG
GAGGAGCTGTACTAGCTAGAGAAACACTAGAGAATCAGGATACAAAAGACAGAAAAGAAATTAATATTCCAACAAAGAAA
ATAATAGCAGAAAAAGCATTTAATTTAATTGAAGATAGAGAAACTATATTTTTAGATATCTCTACAATTAACATCTTGCT
TGCGAAGTTGTTAGCTGAAAGTAATAAAAAAGTAACACTTGTTACAAATATGCTGGATATACTAAATGTAGTTACTTCAA
AACCAAATAATTTAAATATAATTTCCACTGGAGGTTTATTAAATCTCAGTTTAGACGGTTTTGTCGGTACTCCAACTATA
GAGTTTATATCGAAATATAAGTTTGATAAGACTTTTATGGGAAGTTGTGGAGTAGATGTATTCAACTCTTCACTTACAAC
TTTTGAAATTGAAGATGGTCTTACGAAGAAGGCTATAATAAATTCAAGTAAAAAAGTATTTATAGTTATGGAAGATAAAA
AGTTTAAATTTGATGGAAATTTCAAGTTTGCTCATTTAGAAGATATTAGTTCTATAATTACAGAAAAAACGCCTACTCCT
GATATAGTAGATATTTTATCAGAATTTAATGTAAATGTTTTATAA

Upstream 100 bases:

>100_bases
TATATTAAATTAATTTTGTATTTCATGTTAAAATAGTTGATATATTGTATTTTATCTTATAATATTTACTATAATACTAT
ATTGCGAAAAGAGGTAGAAA

Downstream 100 bases:

>100_bases
GTTTAATTATATATTTTATAGGATTTCTTATAAATATAAATTTTTATTTGATAACTATTCTTAAAAACATATTTCTATAA
TATTTATTTTATCCTTAGTA

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIEKISSIRRIYGGAVLARETLENQDTKDRKEINIPTKK
IIAEKAFNLIEDRETIFLDISTINILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFDGNFKFAHLEDISSIITEKTPTP
DIVDILSEFNVNVL

Sequences:

>Translated_254_residues
MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIEKISSIRRIYGGAVLARETLENQDTKDRKEINIPTKK
IIAEKAFNLIEDRETIFLDISTINILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFDGNFKFAHLEDISSIITEKTPTP
DIVDILSEFNVNVL
>Mature_254_residues
MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIEKISSIRRIYGGAVLARETLENQDTKDRKEINIPTKK
IIAEKAFNLIEDRETIFLDISTINILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFDGNFKFAHLEDISSIITEKTPTP
DIVDILSEFNVNVL

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=255, Percent_Identity=32.5490196078431, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1789829, Length=254, Percent_Identity=29.9212598425197, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1788069, Length=255, Percent_Identity=32.156862745098, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787540, Length=239, Percent_Identity=28.4518828451883, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=25.7936507936508, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082344, Length=233, Percent_Identity=21.8884120171674, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI226510968, Length=236, Percent_Identity=25, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789170, Length=240, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28591; Mature: 28591

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIEKISSIRRIYGGAVLAR
CCHHHHHHHHHHHHHHCCCEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDISTINILLAKLLAESNKKVTL
HHHCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCEEEE
VTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTIEFISKYKFDKTFMGSCGVDV
HHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHCCCCHHCCCCCHHH
FNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFDGNFKFAHLEDISSIITEKTPTP
HCCCCEEEEECCCCCHHHHHCCCCEEEEEEECCEEEECCCEEEEHHHHHHHHHHCCCCCC
DIVDILSEFNVNVL
HHHHHHHHCCCCCC
>Mature Secondary Structure
MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIEKISSIRRIYGGAVLAR
CCHHHHHHHHHHHHHHCCCEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDISTINILLAKLLAESNKKVTL
HHHCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCEEEE
VTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTIEFISKYKFDKTFMGSCGVDV
HHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHCCCCHHCCCCCHHH
FNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFDGNFKFAHLEDISSIITEKTPTP
HCCCCEEEEECCCCCHHHHHCCCCEEEEEEECCEEEECCCEEEEHHHHHHHHHHCCCCCC
DIVDILSEFNVNVL
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]