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The map label for this gene is bipA [H]

Identifier: 126699733

GI number: 126699733

Start: 2447691

End: 2449514

Strand: Direct

Name: bipA [H]

Synonym: CD2116

Alternate gene names: 126699733

Gene position: 2447691-2449514 (Clockwise)

Preceding gene: 126699728

Following gene: 126699735

Centisome position: 57.05

GC content: 32.79

Gene sequence:

>1824_bases
ATGTCACAAAAACATAAAATTATAAATATCGCAGTTATAGCCCACGTTGACGCTGGAAAATCAACATTGGTTGATGCTTT
CCTTTCTCAAAGCGGTGTTTTTAGAAAGAACGAAGTAGTTAAAGACTGCGTTATGGACAGTAACGACCTTGAAAAAGAAA
GAGGCATAACTATATATTCAAAAAACTGTGCAATAAACTATGAAGATTACAAAATAAACATAGTTGATACTCCAGGACAC
AGTGACTTTTCTTCTGAAGTTGAACGTGTTATGAAAACTGTTGACACAGTTATTCTATTAGTTGATGCTAGTGAAGGCCC
AATGCCTCAAACTAGATTCGTTTTACAAAAATCTTTAGAGTTCGGTTTAAAACCAATATTATTTATAAACAAGATTGATA
AAAAAGACCAGAGAGCGGAAGAAGTAGTTAATGAAGTTTTCGATTTATTTGTAGACTTAAATGCAACAGATGAGCAATGC
GAATTTCCTATAATATATGGTATTGCTAAACAAGGTATTGCTAAACTTGAAATGGATGATGATAGTGAAGACCTTTCTCC
TCTATTTAAAACTATTGTAAATCACGTTGAAGCTTATCCTAATTACGATAATGAACCTCTACAGTTCCAAATATCAGCTC
TTGCATATGATGATTATGTAGGTAGACTTGGTATAGGTAGAATTTACAAAGGTACTCTTAAAAACAATACACAAGTTGCT
ATATGTAGAGAAGATTCTGTTGTATCTAAAGGAAAAGTATCAAAACTTTCTGTGTATGAAGGTTTAAAACAAGTTGAAGT
TGATGAAGCTACTAGTGGAGAAATAGTTGTTATAGCTGGTATTCCTGATATATCTATAGGTGAAACTATATGCGATTTAG
ATAGTCCACTACCTATGGAAATGATAAAAATAGAAGAGCCTACTCTTTCTATGAACTTCTTAGTAAACGACTCTCCATTC
GTTGGAAAAAGTGGAAAATTCGTTACAACTAGACATTTGAAAGATAGACTTGAAAAAGAACTTGAAGTAAATGTTGGTCT
TAAAGTTGAACCTCTTGATACTACTGATGGATACAAAGTTTCTGGACGTGGAGAGCTTCACTTATCTATACTACTTGAAA
ATATGAGACGTGAAGGTTATGAAGTTGGTGTTTCTAAACCTGAAGTTTTAATGCATAAAGAAGATGGAAAACTAATGGAA
CCAATAGAAAGAGTTGTTGTAAACTGTCCTGAAGTTTACTCTGGTACTATTATAAATGAATTAAACATGAGAAAAGGTAT
GATGGAGTCTATGTCAATAGAAGGAGACTATGTAAAAATAGAGTTCTTAGCACCTACTCGTGGTCTTTTAGGATATCGAA
GTGAATTTATAAACGCTACTCGTGGAGAAGGTACTTTAGTTCGTTCATTTGAAAAATTTGAAGAATTTAAAGGAGAAATA
CCTTCAAGAGGAAATGGTGTTTTAATAGCACAAGGACCTGGTGTTACTATGGGGTATTCTCTTAATGCCTTAAGTGATAG
AGCTGTAATGTTTGTAGACCCTGGTGTAGAAGTTTACGAAGGTATGATAATTGGTATGAATTCCAGAAAAGATGATATGG
TAGTCAACCCTTGTAAAAACAAGAAAATGAGTAACGTACGTGCTTCTGGTTCAGATGATGCTATAAAATTATCTCCTCCT
AGAATATTTACTCTTGAAGAAGCACTAGAGTTTATAGAAGATGATGAATTAGTTGAAATTACACCTGATTCTATAAGACT
TAGAAAAAGATTCTTAAATGAACATGATAGATTAAGATATAACAAATCTAGACAAGGTAAATAA

Upstream 100 bases:

>100_bases
ATTTAAACTATATTAATACAATTTAATATATTCCTCCTTGTACCTAATAATATATTGTGCTATAATTAATAAGTTATTTT
AATCGAAGGGAGCAACAAAA

Downstream 100 bases:

>100_bases
AACGTACATTTACCTCTAATTAACAAAATAGCCATATAGTACTGAAAAATTATTTCAGTTTATATGGCTATTTTTATTTG
AAATTTATATTATTCAACAT

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 607; Mature: 606

Protein sequence:

>607_residues
MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCVMDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGH
SDFSSEVERVMKTVDTVILLVDASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDDYVGRLGIGRIYKGTLKNNTQVA
ICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIVVIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPF
VGKSGKFVTTRHLKDRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMHKEDGKLME
PIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLLGYRSEFINATRGEGTLVRSFEKFEEFKGEI
PSRGNGVLIAQGPGVTMGYSLNALSDRAVMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPP
RIFTLEEALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK

Sequences:

>Translated_607_residues
MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCVMDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGH
SDFSSEVERVMKTVDTVILLVDASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDDYVGRLGIGRIYKGTLKNNTQVA
ICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIVVIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPF
VGKSGKFVTTRHLKDRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMHKEDGKLME
PIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLLGYRSEFINATRGEGTLVRSFEKFEEFKGEI
PSRGNGVLIAQGPGVTMGYSLNALSDRAVMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPP
RIFTLEEALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK
>Mature_606_residues
SQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCVMDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHS
DFSSEVERVMKTVDTVILLVDASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQCE
FPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDDYVGRLGIGRIYKGTLKNNTQVAI
CREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIVVIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFV
GKSGKFVTTRHLKDRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMHKEDGKLMEP
IERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLLGYRSEFINATRGEGTLVRSFEKFEEFKGEIP
SRGNGVLIAQGPGVTMGYSLNALSDRAVMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPR
IFTLEEALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI94966754, Length=132, Percent_Identity=44.6969696969697, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI157426893, Length=495, Percent_Identity=26.0606060606061, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI18390331, Length=134, Percent_Identity=41.044776119403, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI25306287, Length=131, Percent_Identity=39.6946564885496, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4503483, Length=150, Percent_Identity=35.3333333333333, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI19923640, Length=131, Percent_Identity=39.6946564885496, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI25306283, Length=131, Percent_Identity=39.6946564885496, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI310132016, Length=110, Percent_Identity=44.5454545454545, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI310110807, Length=110, Percent_Identity=44.5454545454545, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI310123363, Length=110, Percent_Identity=44.5454545454545, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI34147630, Length=241, Percent_Identity=29.8755186721992, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI217272892, Length=140, Percent_Identity=33.5714285714286, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI217272894, Length=140, Percent_Identity=33.5714285714286, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI94966752, Length=67, Percent_Identity=49.2537313432836, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI48994988, Length=601, Percent_Identity=51.5806988352745, Blast_Score=630, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=510, Percent_Identity=27.4509803921569, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789738, Length=147, Percent_Identity=38.7755102040816, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790835, Length=179, Percent_Identity=29.608938547486, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789737, Length=127, Percent_Identity=33.0708661417323, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790412, Length=127, Percent_Identity=33.0708661417323, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789108, Length=330, Percent_Identity=25.4545454545455, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17556745, Length=143, Percent_Identity=41.2587412587413, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17557151, Length=288, Percent_Identity=28.125, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17506493, Length=178, Percent_Identity=32.0224719101124, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17533571, Length=134, Percent_Identity=35.8208955223881, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71988811, Length=128, Percent_Identity=38.28125, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71988819, Length=128, Percent_Identity=38.28125, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17552882, Length=140, Percent_Identity=33.5714285714286, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17556456, Length=283, Percent_Identity=27.5618374558304, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115532065, Length=234, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532067, Length=234, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25141371, Length=240, Percent_Identity=27.5, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=465, Percent_Identity=27.5268817204301, Blast_Score=117, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6324707, Length=150, Percent_Identity=35.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320593, Length=150, Percent_Identity=35.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322359, Length=150, Percent_Identity=36.6666666666667, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6323098, Length=139, Percent_Identity=35.2517985611511, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324761, Length=270, Percent_Identity=25.1851851851852, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324166, Length=142, Percent_Identity=35.9154929577465, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322937, Length=202, Percent_Identity=27.2277227722772, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI78706572, Length=482, Percent_Identity=25.5186721991701, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28574573, Length=141, Percent_Identity=39.0070921985816, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585709, Length=170, Percent_Identity=33.5294117647059, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24585711, Length=170, Percent_Identity=33.5294117647059, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24585713, Length=170, Percent_Identity=33.5294117647059, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24582462, Length=146, Percent_Identity=35.6164383561644, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI221458488, Length=149, Percent_Identity=38.255033557047, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19921738, Length=238, Percent_Identity=29.8319327731092, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=34.3283582089552, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI281363316, Length=319, Percent_Identity=23.5109717868339, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17864358, Length=319, Percent_Identity=23.5109717868339, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 68038; Mature: 67907

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCVMDSNDLEKERGITIYS
CCCCCEEEEEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHCCEEEEE
KNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVDASEGPMPQTRFVLQKSLE
CCEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHH
FGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQCEFPIIYGIAKQGIAKLEMDD
HCCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEHHCCCEEEECCC
DSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDDYVGRLGIGRIYKGTLKNNTQVA
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEHHHHCCCCCCCEEECCCCCCCEEE
ICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIVVIAGIPDISIGETICDLDSPLPME
EEECCCCCCCCCCCEEHHHHCHHHEECCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCCE
MIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLKDRLEKELEVNVGLKVEPLDTTDGYKV
EEEECCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHEEECCEEEEECCCCCCEEE
SGRGELHLSILLENMRREGYEVGVSKPEVLMHKEDGKLMEPIERVVVNCPEVYSGTIINE
CCCCCEEHHHHHHHHHHCCEEECCCCCEEEEECCCCCHHHHHHHHHHCCCCHHCCCEEEH
LNMRKGMMESMSIEGDYVKIEFLAPTRGLLGYRSEFINATRGEGTLVRSFEKFEEFKGEI
HHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC
PSRGNGVLIAQGPGVTMGYSLNALSDRAVMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKN
CCCCCEEEEECCCCEEEEEEECCCCCCEEEEECCCHHHHCCEEEECCCCCCCEEECCCCC
KKMSNVRASGSDDAIKLSPPRIFTLEEALEFIEDDELVEITPDSIRLRKRFLNEHDRLRY
CCCCCCCCCCCCCEEEECCCEEEEHHHHHHHHCCCCEEEECCHHHHHHHHHHCHHHHHEE
NKSRQGK
CCCCCCC
>Mature Secondary Structure 
SQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCVMDSNDLEKERGITIYS
CCCCEEEEEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHCCEEEEE
KNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVDASEGPMPQTRFVLQKSLE
CCEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHH
FGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQCEFPIIYGIAKQGIAKLEMDD
HCCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEHHCCCEEEECCC
DSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDDYVGRLGIGRIYKGTLKNNTQVA
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEHHHHCCCCCCCEEECCCCCCCEEE
ICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIVVIAGIPDISIGETICDLDSPLPME
EEECCCCCCCCCCCEEHHHHCHHHEECCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCCE
MIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLKDRLEKELEVNVGLKVEPLDTTDGYKV
EEEECCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHEEECCEEEEECCCCCCEEE
SGRGELHLSILLENMRREGYEVGVSKPEVLMHKEDGKLMEPIERVVVNCPEVYSGTIINE
CCCCCEEHHHHHHHHHHCCEEECCCCCEEEEECCCCCHHHHHHHHHHCCCCHHCCCEEEH
LNMRKGMMESMSIEGDYVKIEFLAPTRGLLGYRSEFINATRGEGTLVRSFEKFEEFKGEI
HHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC
PSRGNGVLIAQGPGVTMGYSLNALSDRAVMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKN
CCCCCEEEEECCCCEEEEEEECCCCCCEEEEECCCHHHHCCEEEECCCCCCCEEECCCCC
KKMSNVRASGSDDAIKLSPPRIFTLEEALEFIEDDELVEITPDSIRLRKRFLNEHDRLRY
CCCCCCCCCCCCCEEEECCCEEEEHHHHHHHHCCCCEEEECCHHHHHHHHHHCHHHHHEE
NKSRQGK
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]