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The map label for this gene is hgdC [H]

Identifier: 126699357

GI number: 126699357

Start: 2027214

End: 2027969

Strand: Direct

Name: hgdC [H]

Synonym: CD1750

Alternate gene names: 126699357

Gene position: 2027214-2027969 (Clockwise)

Preceding gene: 126699356

Following gene: 126699358

Centisome position: 47.25

GC content: 32.67

Gene sequence:

>756_bases
ATGTTTAGTATAGGAGTTGACTCAGGGTCAGTGGCAACAAAGGGTGTGCTATTTGATGGTGAAAAAATTATTAAGAAAAT
AATTATACCAACTGGATGGAGCCCTAAAAGTACATCTAAACAGGTCTATGAGTTGCTAAGTAGTGAAATTGACAAAAAAG
ATATAAAAAAGGTGGTAGGTACAGGTTATGGAAGGGGAGTAATGGATTTTGCTGATAAGAAAGTAACAGAAATAACTTGT
CATACTAGAGGTATTTACTTTTTAAACAAGAACATAAGGACTATTTTAGATGTAGGTGGTCAAGATAGTAAAGTTATAAA
TTTAGATAGAGATGGAAATGTATTTAACTTTATAATGAATGATAAGTGTGCTGCAGGAACTGGTCGATTTTTAGAGATTA
CTTCTAACCTTTTAGGAAGCGATATTGAAAGTATAGATACATTAGCTAAAGGATATGAACCAGTTAATATATCTAGTATG
TGTACAGTTTTTGCTGAGTCTGAAATTGTAAGTCTTCTAGCTCAAAACATTTCTACTGGAGAGGTAGCAGCAGGGATACT
TAAATCTATTGCAAATAAATCCACCTCAATGTTAGCAAGAGGTGAGGTAATAGATGAAGTTGCATTTACTGGAGGGCTTG
CAAAAAGTAAAGAACTAGTAAAAATGATAGAAGAAATACTGGGTAAAAAAATTTTTATTGCAGAAGATACTCAAATAATA
GGAGCTTTAGGAGCTGCTGTAATAGGATTTAGATAA

Upstream 100 bases:

>100_bases
TCTTGAAACTGATTATTCAAAATCAGATACTGAACAATTAAGAACTAGATTTGAAGCGTTTGTAGAGATGTTGTAGGAAT
AAATAAAAGTAGGAGGAACT

Downstream 100 bases:

>100_bases
AAACATATAAAAAGAAAATGAGAAGCTGAATTTATTATAAATAAATTCAGTTTTTTATTTTATTTTATTTATTTATAAAG
GAAAACTTTGGTATAATTGA

Product: (R)-2-hydroxyglutaryl-CoA dehydratase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYELLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITC
HTRGIYFLNKNIRTILDVGGQDSKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKELVKMIEEILGKKIFIAEDTQII
GALGAAVIGFR

Sequences:

>Translated_251_residues
MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYELLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITC
HTRGIYFLNKNIRTILDVGGQDSKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKELVKMIEEILGKKIFIAEDTQII
GALGAAVIGFR
>Mature_251_residues
MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYELLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITC
HTRGIYFLNKNIRTILDVGGQDSKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKELVKMIEEILGKKIFIAEDTQII
GALGAAVIGFR

Specific function: Unknown

COG id: COG1924

COG function: function code I; Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082426, Length=250, Percent_Identity=44, Blast_Score=232, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002731
- InterPro:   IPR008275 [H]

Pfam domain/function: PF01869 BcrAD_BadFG [H]

EC number: NA

Molecular weight: Translated: 26942; Mature: 26942

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYELLSSEIDKKDIKKVVG
CEEECCCCCCCEECCEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHH
TGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQDSKVINLDRDGNVFNFIMN
CCCCCCHHHHHCCHHEEEEEECCEEEEECCCCCEEHHCCCCCCEEEEECCCCCEEEEEEC
DKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSMCTVFAESEIVSLLAQNISTG
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
EVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKELVKMIEEILGKKIFIAEDTQII
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCHHHH
GALGAAVIGFR
HHHHHHHHCCC
>Mature Secondary Structure
MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYELLSSEIDKKDIKKVVG
CEEECCCCCCCEECCEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHH
TGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQDSKVINLDRDGNVFNFIMN
CCCCCCHHHHHCCHHEEEEEECCEEEEECCCCCEEHHCCCCCCEEEEECCCCCEEEEEEC
DKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSMCTVFAESEIVSLLAQNISTG
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCH
EVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKELVKMIEEILGKKIFIAEDTQII
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCHHHH
GALGAAVIGFR
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]