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The map label for this gene is lytT [H]

Identifier: 126699349

GI number: 126699349

Start: 2018941

End: 2019648

Strand: Direct

Name: lytT [H]

Synonym: CD1743

Alternate gene names: 126699349

Gene position: 2018941-2019648 (Clockwise)

Preceding gene: 126699348

Following gene: 126699350

Centisome position: 47.06

GC content: 25.14

Gene sequence:

>708_bases
TTGATTTCAATTGCCATTTGTGATGATGAATCCTATATGCTAAATCATTTAAAGGAAAATATAGAATTATACATGAAGCA
GAAGAATTTATTATATAATATAGAGCTTTTTAATAAAGTAGAAAATTTACTATGCAATCATGAAAAGTTTAATATTGTAT
TTTTAGATATACAGATGGAAGAGATTAACGGAATGCAGGCAGCTAGAAAATTAAGGTCATATGGTAATGAGTGCTTTATA
ATTTTCGTTACAGTTTTAAATGAATTTGTATTTGATGCTTTTGAAGTAGATGCTATAAATTATCTGATAAAACCTCTATC
TAATGAGAAACTATATAAAACTTTGGATAAAATAGTTACAAAACTTGATGATAATGAAAGTAATTATATCACAATACAAA
AAGGTTATTCATATTGGAAATTAAAACTTGCTGATATTTTATATTGTGAAGTTATAAAAAGAAAGATTTATGTTCATTTA
AAGAAAGAGACTGTAGATTATTATGAGACTATTGAAAATTTAGAGAGAAGTTTACCAACAAATTTTTTTAGGTGTCATCG
TAGTTATATAATCAATTTACAATATGTATATGGATATGAAAATGGTAATGCAGTTATGGAAAGTGGAGATAGAATACCTG
TTTCTAGACTACGTCAACAAATATTTTCAAAAGTTATGCTTGAGTTCATGAAAAATAGGAGGATATAA

Upstream 100 bases:

>100_bases
TTTTGGAACAAATATTCAACATATTAGATCATATTAATTGAACAGAAAAAATTAACTTTATATAATAATTAGAATAATGA
TAAGAAAGAAGGTGTATATA

Downstream 100 bases:

>100_bases
GATGATTAATTTATTTTCTTCCGATTTATTTTTAAAGTACAGTTTTTTCTTCTCTTTTATTGTATATAGAATTTTAATGG
TAATAGTGCAATACTATTTT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MISIAICDDESYMLNHLKENIELYMKQKNLLYNIELFNKVENLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFI
IFVTVLNEFVFDAFEVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVIKRKIYVHL
KKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGDRIPVSRLRQQIFSKVMLEFMKNRRI

Sequences:

>Translated_235_residues
MISIAICDDESYMLNHLKENIELYMKQKNLLYNIELFNKVENLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFI
IFVTVLNEFVFDAFEVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVIKRKIYVHL
KKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGDRIPVSRLRQQIFSKVMLEFMKNRRI
>Mature_235_residues
MISIAICDDESYMLNHLKENIELYMKQKNLLYNIELFNKVENLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFI
IFVTVLNEFVFDAFEVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVIKRKIYVHL
KKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGDRIPVSRLRQQIFSKVMLEFMKNRRI

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=234, Percent_Identity=28.6324786324786, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788724, Length=200, Percent_Identity=25.5, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28140; Mature: 28140

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISIAICDDESYMLNHLKENIELYMKQKNLLYNIELFNKVENLLCNHEKFNIVFLDIQME
CEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCEEEEEEEEEHH
EINGMQAARKLRSYGNECFIIFVTVLNEFVFDAFEVDAINYLIKPLSNEKLYKTLDKIVT
HHCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KLDDNESNYITIQKGYSYWKLKLADILYCEVIKRKIYVHLKKETVDYYETIENLERSLPT
HCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHCCH
NFFRCHRSYIINLQYVYGYENGNAVMESGDRIPVSRLRQQIFSKVMLEFMKNRRI
HHHHHHHHHEEEEEEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MISIAICDDESYMLNHLKENIELYMKQKNLLYNIELFNKVENLLCNHEKFNIVFLDIQME
CEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCEEEEEEEEEHH
EINGMQAARKLRSYGNECFIIFVTVLNEFVFDAFEVDAINYLIKPLSNEKLYKTLDKIVT
HHCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KLDDNESNYITIQKGYSYWKLKLADILYCEVIKRKIYVHLKKETVDYYETIENLERSLPT
HCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHCCH
NFFRCHRSYIINLQYVYGYENGNAVMESGDRIPVSRLRQQIFSKVMLEFMKNRRI
HHHHHHHHHEEEEEEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]