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The map label for this gene is resE [H]

Identifier: 126699182

GI number: 126699182

Start: 1828996

End: 1830852

Strand: Direct

Name: resE [H]

Synonym: CD1579

Alternate gene names: 126699182

Gene position: 1828996-1830852 (Clockwise)

Preceding gene: 126699181

Following gene: 126699183

Centisome position: 42.63

GC content: 25.09

Gene sequence:

>1857_bases
ATGGATACCCATAATAAATATGTAAATTTTATAAAAAATATACCTGTACCTTTTTTATATTGTAGAATTGTAAAGAGACA
AGAAGATATAGAATATCGAGTAGAATATATAAGTAAGGGTATGGGCAAAGTATTACAATTAGAAGAAGGTATTTGTGATA
AAAATATACTAGATGTATTGCCTGTATTTAAGTCTAAAAAATATTTCAAAGAGTTGTTCTCAAATGAAGTGGATTGTATA
AAAAGGTACATTCCGACACTTAAAAACTGGATAAATATAAAAAAACAGATAATAGGGGATTCATACATAATTTTGTATTT
TGGTAAAATTGTATTTGATTATAGACAGATAATCGATTCCTTTGATAAAAAGGAAAAAGTAGCTTATATTAAAGACGAAG
AAGGCATATATATAGATTGCAGTGAAAATTTAATACCAATATTAAATAACAACATTAAAACAACGAAAGATATCTTTGGT
AAAAATGATATAGAAGTATGGGGAGAGAATACAGGAAAATTATTTAGAGATGATTATAGAGAAGGAGTATCTAGTAAAAA
AAGATTTTTACAAAATCTTTTTGAATATGAAGAAACATTTTTTATGGTTGAAAAATATTTTTTGTATGATGAAGACGAAC
TTTTAGGTACTATAGGGATAGTAGACAATATAATATATAGTGGTTACAGTAATAGAAATTATAACTCAAAAGATTTAATG
AAGATGATAGAACACTCAATTCCAGAGAATATGTTTTATAAAGATGTGTATGGAAATTATATTGGATTTAATTCAGGTTT
TTTGAATTTAGCTTGTATGAATAAAGAAGAATTATTAGGGAAGAATAGTTATAAAATATCAGAAGAAGAAGCTTTAATAG
ATAAGATTTTTGAAAGTGATAAGGGTGTAGTTGAAAATAAAAAAGTAGTTACATTTGAGTTAAATATAAGTATGAATGAT
GAAAACAAGTGTATTGAGATTACAAAAAGGCCGTTTTTTGATAGCTATGGAAGTGTTATTGGAATAATTGGAACAGCAAG
GGATATAAGTAGAAGAAAAAGATTAGAAGAGGAAATGGATAAAACTAGGATGGAATTTTTTGCAAATTTATCCCATGAAC
TTAGAACGCCTATAAATTTAATATCATCTTCATTACAAGTGATAGAAAAAAAAGAAGCAGATTTAATAGAATCAAATGAT
ACTTTAAAAAGAAATCTAGGTATAATAAAACAAAATGGAAATAGAATATTGAGGTTAGTAAATAATGTTATAGACTTTAC
AAAAATGCAATCAGGATATTTAGATTTTAAACCAGAAGAATCTGATATAATTGCATTTATAGAGGAGATATGTATGTCTG
TAGCTGATTTTGCAAGCCAAAATAATATACAACTTACATTTGATACAGAAATAGAAGAATTTTCAATGTTATTTGATTCA
GAAAAATTGGAAAGAATAATATTAAATTTACTTTCTAATGGAATTAAGTACAATAAGAAAGATGGAAAAATAAATATATT
TTTATATGTGAAAGATAATGTATTTAATATGAAAATATCTGATAGTGGTATAGGTATACCAAAAGAAAAAATAGATAAAA
TATTTAATAGGTTTGAACAGATTGACAATGAACTTTCTTACAGAGTTAAAGGAAGTGGTATTGGACTTTCATTAGTGAAA
TCTTTGGTTGAGTTGCATGAGGGAAGTATATCTTTAAAAAGTCAACTTGGTATTGGAAGTGAATTTATAGTTTCATTGCC
TGTTAGAAGTAAAAATAATATTGAAAAATATAATCATAAAAGAGAAATCAGCAATGAACTAAGTAAAAAATTAGAAATAG
AGTTCTCGGATTTATAA

Upstream 100 bases:

>100_bases
CAAGTATATCTTATAAAATATGTTATAATTAATAGAAAATTGTCATATAATTAATTAAGTAGTATTATTATAAATAACAT
TGAAAGGTAGTGGTTAGAAT

Downstream 100 bases:

>100_bases
GTTTAAATATAAAAAATAAAATTTTAAAAAAGTATTGACAATTGATTTAGAAGGGTTTAAAATAAATTACAACATAATAA
ATAAAAAGGCGATGAATAGG

Product: two-component histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKVLQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCI
KRYIPTLKNWINIKKQIIGDSYIILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTIGIVDNIIYSGYSNRNYNSKDLM
KMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKEELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMND
ENKCIEITKRPFFDSYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKEADLIESND
TLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEICMSVADFASQNNIQLTFDTEIEEFSMLFDS
EKLERIILNLLSNGIKYNKKDGKINIFLYVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVK
SLVELHEGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL

Sequences:

>Translated_618_residues
MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKVLQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCI
KRYIPTLKNWINIKKQIIGDSYIILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTIGIVDNIIYSGYSNRNYNSKDLM
KMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKEELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMND
ENKCIEITKRPFFDSYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKEADLIESND
TLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEICMSVADFASQNNIQLTFDTEIEEFSMLFDS
EKLERIILNLLSNGIKYNKKDGKINIFLYVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVK
SLVELHEGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL
>Mature_618_residues
MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKVLQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCI
KRYIPTLKNWINIKKQIIGDSYIILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTIGIVDNIIYSGYSNRNYNSKDLM
KMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKEELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMND
ENKCIEITKRPFFDSYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKEADLIESND
TLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEICMSVADFASQNNIQLTFDTEIEEFSMLFDS
EKLERIILNLLSNGIKYNKKDGKINIFLYVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVK
SLVELHEGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=352, Percent_Identity=26.4204545454545, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788713, Length=403, Percent_Identity=25.8064516129032, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=31.6455696202532, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI145693157, Length=270, Percent_Identity=26.2962962962963, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=27.2727272727273, Blast_Score=109, Evalue=7e-25,
Organism=Escherichia coli, GI1786600, Length=276, Percent_Identity=24.6376811594203, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788549, Length=364, Percent_Identity=21.1538461538462, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=24.4897959183673, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790436, Length=257, Percent_Identity=25.2918287937743, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=25.9911894273128, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081816, Length=245, Percent_Identity=25.7142857142857, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788279, Length=226, Percent_Identity=28.3185840707965, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=23.3050847457627, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=21.4592274678112, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71998; Mature: 71998

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKVLQLEEGICDKNILDVL
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
PVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSYIILYFGKIVFDYRQIIDS
HHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHH
FDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFGKNDIEVWGENTGKLFRDDYR
HCCCCCEEEEECCCCEEEECCCCEEHHHCCCCCCHHHHCCCCCEEECCCCCCHHHHHHHH
EGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTIGIVDNIIYSGYSNRNYNSKDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKEELLGKNSYKISEEEALIDKIFESD
HHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHCC
KGVVENKKVVTFELNISMNDENKCIEITKRPFFDSYGSVIGIIGTARDISRRKRLEEEMD
CCCCCCCEEEEEEEEEEECCCCCEEEEECCCCHHCCCCCEEECCCHHHHHHHHHHHHHHH
KTRMEFFANLSHELRTPINLISSSLQVIEKKEADLIESNDTLKRNLGIIKQNGNRILRLV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEECCHHHHHHH
NNVIDFTKMQSGYLDFKPEESDIIAFIEEICMSVADFASQNNIQLTFDTEIEEFSMLFDS
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCH
EKLERIILNLLSNGIKYNKKDGKINIFLYVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQ
HHHHHHHHHHHHCCCEECCCCCEEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHH
IDNELSYRVKGSGIGLSLVKSLVELHEGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHK
HCCHHEEEECCCCCCHHHHHHHHHHHCCCEEEHHHCCCCCEEEEEECCCCCCCHHHHHHH
REISNELSKKLEIEFSDL
HHHHHHHHHHCCEEECCC
>Mature Secondary Structure
MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKVLQLEEGICDKNILDVL
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
PVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSYIILYFGKIVFDYRQIIDS
HHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHH
FDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFGKNDIEVWGENTGKLFRDDYR
HCCCCCEEEEECCCCEEEECCCCEEHHHCCCCCCHHHHCCCCCEEECCCCCCHHHHHHHH
EGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTIGIVDNIIYSGYSNRNYNSKDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKEELLGKNSYKISEEEALIDKIFESD
HHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHCC
KGVVENKKVVTFELNISMNDENKCIEITKRPFFDSYGSVIGIIGTARDISRRKRLEEEMD
CCCCCCCEEEEEEEEEEECCCCCEEEEECCCCHHCCCCCEEECCCHHHHHHHHHHHHHHH
KTRMEFFANLSHELRTPINLISSSLQVIEKKEADLIESNDTLKRNLGIIKQNGNRILRLV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEECCHHHHHHH
NNVIDFTKMQSGYLDFKPEESDIIAFIEEICMSVADFASQNNIQLTFDTEIEEFSMLFDS
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCH
EKLERIILNLLSNGIKYNKKDGKINIFLYVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQ
HHHHHHHHHHHHCCCEECCCCCEEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHH
IDNELSYRVKGSGIGLSLVKSLVELHEGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHK
HCCHHEEEECCCCCCHHHHHHHHHHHCCCEEEHHHCCCCCEEEEEECCCCCCCHHHHHHH
REISNELSKKLEIEFSDL
HHHHHHHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]