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The map label for this gene is cinA

Identifier: 126699012

GI number: 126699012

Start: 1633314

End: 1634570

Strand: Direct

Name: cinA

Synonym: CD1409

Alternate gene names: 126699012

Gene position: 1633314-1634570 (Clockwise)

Preceding gene: 126699007

Following gene: 126699013

Centisome position: 38.07

GC content: 32.06

Gene sequence:

>1257_bases
TTGAAAGCTGAAATAATAAGTGTAGGAACAGAAATATTATTGGGAGATATAGTAAATACAAATTCTCAATTTTTAGCTAA
AGAACTTGCATCATTGGGAATAGAAGTATACCATCAGAGTACTGTTGGAGATAACAAACAAAGACTTTTAGAATGTTTTG
ATGAAAGCTTAAAGAGAAGTGATTTTGTAATTACTACAGGTGGTCTTGGGCCAACTGGTGATGATATGACAAAAGAAACT
GCTGCAGAATACTTTGGTCAGAAATTAGAACTACATAAACCTTCACTAGAGGTTTTGGAATCTTTCTTTGTTAAAACAGG
GAAAAAAATGGCCGAAAATAATATGAAACAAGTGTACTTTCCAAAAGATGCTATAGTACTAAAAAATAATAATGGTACAG
CTCCAGGGGCAATTTTAAAAAAAGATGGTAAATTTATAATAGTATTGCCTGGACCTCCAAGAGAAATGAAAGCTATGTTT
AATGAGAGTGTCAAACCTTACTTACAACAATTCACAAATGAAATGCTAGTATCTAAGACTTTAAGATTATATGGAATAGG
TGAGTCAAATCTAGAATTAGAAATTCTCGATATAATTAATGAGCAGACTAATCCAACAGTTGCTTTATATGCAAAAGAAT
TAGAAGTTACAATAAGAATAACTGCAAAGGCTGAAAATGAAAGAGAAGCTTTTAAATTAATAAAACCAGTAGAAGAAAAA
ATAAAAAGTAGAGTTGGTAAATATGTATATACTGAAGGAGATATTTCCATATCTGAAGGGGAGACTGCTTTAGAAGATGC
TGTTTCTAAGCTACTTGTAGAAAAAAATCTAACAATAGCAGTGGCTGAATCTTGTACTGGAGGTTTGGTTTCTTCATCTC
TTATAAACTATCCAGGTATATCCTCTGTATTTCTTGAAGGTTGTGTAACATATTCTAATGATTCTAAAATGAAAAGATTA
GGAGTAAAAAGAGAAACTTTGGAAGAGTTTGGAGCAGTAAGTGAGCAAACAGCTATAGAAATGGCTGAGGGCGTTGCTAA
AGGACTTAAAGCTAATATAGGTATATCCACAACTGGAGTAGCTGGACCTGGTGGAGGAACCAAAGAGAAGCCTGTGGGAC
TGGTTTATACTGCAATATATATAAATGGAAAAACAATAGTAAAGAAAAATATATTTAATGGGGATAGAAGAAAGATAAGA
TTAAGAGCTACTAGAGATTTGCTTAATGAATTGAGAATACAATTAGAAAAGCTTTAA

Upstream 100 bases:

>100_bases
AAATGATTTTTTAACTTTATTTATGTTATTATTTTTGCTAAAATTATTGTTATGAACTTAAGACTAGTCTTAATGGCTAT
AAATCAAGGAGTGATAAATT

Downstream 100 bases:

>100_bases
GTTATTTTGATTAAAGTATTAGTAAAATATAAAATTGTTTTTGGAGGCTTTTAATTTATGATAAAACATATATTTTGTGA
TTTAGATGGAACTCTATATG

Product: competence damage-inducible protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGDNKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKET
AAEYFGQKLELHKPSLEVLESFFVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTIRITAKAENEREAFKLIKPVEEK
IKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKNLTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRL
GVKRETLEEFGAVSEQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIFNGDRRKIR
LRATRDLLNELRIQLEKL

Sequences:

>Translated_418_residues
MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGDNKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKET
AAEYFGQKLELHKPSLEVLESFFVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTIRITAKAENEREAFKLIKPVEEK
IKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKNLTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRL
GVKRETLEEFGAVSEQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIFNGDRRKIR
LRATRDLLNELRIQLEKL
>Mature_418_residues
MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGDNKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKET
AAEYFGQKLELHKPSLEVLESFFVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTIRITAKAENEREAFKLIKPVEEK
IKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKNLTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRL
GVKRETLEEFGAVSEQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIFNGDRRKIR
LRATRDLLNELRIQLEKL

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Homo sapiens, GI41872403, Length=98, Percent_Identity=41.8367346938776, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI41872389, Length=96, Percent_Identity=42.7083333333333, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI296434309, Length=97, Percent_Identity=42.2680412371134, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788583, Length=295, Percent_Identity=30.5084745762712, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1789052, Length=153, Percent_Identity=41.8300653594771, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1787818, Length=142, Percent_Identity=36.6197183098592, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71993966, Length=111, Percent_Identity=35.1351351351351, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71993974, Length=111, Percent_Identity=35.1351351351351, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323832, Length=212, Percent_Identity=30.188679245283, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINA_CLOD6 (Q18BS8)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001087909.1
- ProteinModelPortal:   Q18BS8
- STRING:   Q18BS8
- GeneID:   4914970
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD1409
- NMPDR:   fig|1496.1.peg.3527
- eggNOG:   COG1058
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- ProtClustDB:   PRK00549
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 45903; Mature: 45903

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGDNKQRLLECFDESLKRS
CCCEEEECCHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCC
DFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESFFVKTGKKMAENNMKQVYF
CEEEEECCCCCCCCCHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCHHHHHCCCCEEEE
PKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMFNESVKPYLQQFTNEMLVSKT
CCCEEEEECCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTIRITAKAENEREAFKLIKPVEEK
HHEEECCCCCCCEEEEEHHCCCCCCEEEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHH
IKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKNLTIAVAESCTGGLVSSSLINYPGI
HHHHHCCEEEECCCEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCH
SSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVSEQTAIEMAEGVAKGLKANIGISTTGV
HHHHHHHHEEECCCCHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEECCC
AGPGGGTKEKPVGLVYTAIYINGKTIVKKNIFNGDRRKIRLRATRDLLNELRIQLEKL
CCCCCCCCCCCCEEEEEEEEECCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGDNKQRLLECFDESLKRS
CCCEEEECCHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCC
DFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESFFVKTGKKMAENNMKQVYF
CEEEEECCCCCCCCCHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCHHHHHCCCCEEEE
PKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMFNESVKPYLQQFTNEMLVSKT
CCCEEEEECCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTIRITAKAENEREAFKLIKPVEEK
HHEEECCCCCCCEEEEEHHCCCCCCEEEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHH
IKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKNLTIAVAESCTGGLVSSSLINYPGI
HHHHHCCEEEECCCEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCH
SSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVSEQTAIEMAEGVAKGLKANIGISTTGV
HHHHHHHHEEECCCCHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEECCC
AGPGGGTKEKPVGLVYTAIYINGKTIVKKNIFNGDRRKIRLRATRDLLNELRIQLEKL
CCCCCCCCCCCCEEEEEEEEECCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA