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The map label for this gene is selU [H]

Identifier: 126698924

GI number: 126698924

Start: 1536707

End: 1537765

Strand: Direct

Name: selU [H]

Synonym: CD1325

Alternate gene names: 126698924

Gene position: 1536707-1537765 (Clockwise)

Preceding gene: 126698923

Following gene: 126698925

Centisome position: 35.82

GC content: 27.86

Gene sequence:

>1059_bases
TTGTCAGTTATAAAAATAGAAAAAGCACTTAAGCTAGATAAAGTAATATTTGTAGATGTGAGAACTGAAGGAGAATATGA
AGAAGACCATATATTGAATGCAATCAATATGCCTCTTTTTAAAAATAATGAACATAATGAAGTTGGAACAATTTATAAGA
TGCAGGGAAAACATGAAGCAATACAAAAAGGGTTTGACTATGTATCGTATAAATTAAAGGATATATATTTACAAGCAGCA
GAACTTGCATTAAATTATGATAATATTGTCATATATTGTGCAAGAGGCGGAATGAGAAGTGGAAGTATAGTAAATTTATT
ATCATCATTAGGTGTAAATGTATATCAACTTGAAGGTGGATATAAGGCTTATAGAAATTTTGTTTTAGAGTATTTAAGGC
ATGTAATGGATACAAAAAACTTTGTATCTGTTCATGGATTGACTGGTACAGGAAAGACTGATTTGTTACATTTATTAGAT
GAAAACGGAATAGATGTACTGGATTTAGAAGGCATAGCTAAAAACAGTGGTTCTACCTTTGGTTTTATAACTTTTGATAA
AAAGCCACCATCTCAAAAGAACTTTGAAACAAAACTATTTGAAAGTATATTTTTTTCGAAAGAGAATTATATATTTGTCG
AGAGTGAAAGCAAACGAGTTGGAAGTGTTACAGTTCCAAATGAAATTTTCGAGGCAATGACACGAGAAGGACATCATATA
TTATTAGAATGTGATATTGAAAATAGAGTTGATAGACTTTGTAGAGATTATATTTATGATAAAGATGAAGGTAATATATT
GATTTTAAAAGAATGTATAAACAAGTTTAGAAAAAGATTGGGTAATAAAGTAGTAGATGATTATATTGATTTATTAGAAT
CAGGTGAATATAAAGAACTTGTAAAAAGATATCTTTTAGAATACTACGACCCACTTTATATGCATTCAGTAGAGAAATAT
AAGTATAGTAAGATTATAAATTTTAATGATACACAAAAAGCTTTAGAAGATGTTATAGACTTATATGAGAGTATATTGGA
AGGAGAAAGTGAATGTTAA

Upstream 100 bases:

>100_bases
CTATGGAAGAAAGAGGAATAATTGGAGCAAGTGAGGGAAGTAAACCGAGAAAGGTATTAATAAGCAAACAGGATTTGCAG
AATTTAGAAGGTGAATAGAA

Downstream 100 bases:

>100_bases
AAATAGCATTGGAATCATTAGGATGCTCAAAAAATTTAGTAGATGCAGAAATAATGATGGGAATTTTAAATAACAAAGGC
TATAAATTAATTGGAGATTT

Product: tRNA 2-selenouridine synthase

Products: NA

Alternate protein names: Selenophosphate-dependent tRNA 2-selenouridine synthase [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNEHNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAA
ELALNYDNIVIYCARGGMRSGSIVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
ENGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESKRVGSVTVPNEIFEAMTREGHHI
LLECDIENRVDRLCRDYIYDKDEGNILILKECINKFRKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKY
KYSKIINFNDTQKALEDVIDLYESILEGESEC

Sequences:

>Translated_352_residues
MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNEHNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAA
ELALNYDNIVIYCARGGMRSGSIVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
ENGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESKRVGSVTVPNEIFEAMTREGHHI
LLECDIENRVDRLCRDYIYDKDEGNILILKECINKFRKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKY
KYSKIINFNDTQKALEDVIDLYESILEGESEC
>Mature_351_residues
SVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNEHNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAE
LALNYDNIVIYCARGGMRSGSIVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLDE
NGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESKRVGSVTVPNEIFEAMTREGHHIL
LECDIENRVDRLCRDYIYDKDEGNILILKECINKFRKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYK
YSKIINFNDTQKALEDVIDLYESILEGESEC

Specific function: Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA [H]

COG id: COG2603

COG function: function code R; Predicted ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Escherichia coli, GI1786712, Length=348, Percent_Identity=29.8850574712644, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR017582 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40727; Mature: 40596

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNEHNEVGTIYKMQGKHEA
CCEEEHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCEECCCCCCCCCEEEEECCHHHH
IQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGSIVNLLSSLGVNVYQLEGG
HHHCHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEECCC
YKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLDENGIDVLDLEGIAKNSGSTF
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCEE
GFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESKRVGSVTVPNEIFEAMTREGHHI
EEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCHHHHHHHHCCCCEE
LLECDIENRVDRLCRDYIYDKDEGNILILKECINKFRKRLGNKVVDDYIDLLESGEYKEL
EEEECHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHH
VKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKALEDVIDLYESILEGESEC
HHHHHHHHCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNEHNEVGTIYKMQGKHEA
CEEEHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCEECCCCCCCCCEEEEECCHHHH
IQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGSIVNLLSSLGVNVYQLEGG
HHHCHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEECCC
YKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLDENGIDVLDLEGIAKNSGSTF
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCEE
GFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESKRVGSVTVPNEIFEAMTREGHHI
EEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCHHHHHHHHCCCCEE
LLECDIENRVDRLCRDYIYDKDEGNILILKECINKFRKRLGNKVVDDYIDLLESGEYKEL
EEEECHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHH
VKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKALEDVIDLYESILEGESEC
HHHHHHHHCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA