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The map label for this gene is ftsK [H]

Identifier: 126698923

GI number: 126698923

Start: 1534293

End: 1536704

Strand: Direct

Name: ftsK [H]

Synonym: CD1324

Alternate gene names: 126698923

Gene position: 1534293-1536704 (Clockwise)

Preceding gene: 126698922

Following gene: 126698924

Centisome position: 35.76

GC content: 31.01

Gene sequence:

>2412_bases
ATGGCCACGAAAAAGAAGAAAAAAAAGAAGGTAAATACCTTAAGTTTTAATGCAGAATATCATAATTTAATAACAATATT
TATAGGTGTATTTTTATTATATAGTTTAAATTCTAATTCTATGGGATGGATACCTGTGTTAATGCAAAATCTTTTTAAGG
GACTATTTGGAGGGCTTTCAATAGCAATACCATTTATAGTAATTATAACAGGACTTTTAGGATTTTTTGATGGAAATGAA
TATATATATAGGCTAAGAAAGACTAAACTATACTACATAATTATTTTATTTATATTTGTATTTTATGGATTATTAAATGC
AGGAACTCTTCCTGTAGATAGCCCACTAAAAGGTAACATGTTTGATGATGTTATGAAATTGGGTGTAAGTGGACAAGGTA
GTGGTTTGATAGCAACAACTATTGCGTATTATATGAGTAAAATATTTGGTATAGCAGGTGGATGGTTAATAAGTATCTTC
GCACTTATACTTTCTGTAATGTTTATATTTAATATTTCTATAAAAGATTTGGTGTCAAATGCAAAATCAAAATCTAAAGC
ATCTAAAGACAGCAATTTAACGTTTAAAGATAAAATTGCAAATATGAAAAAATCTGCAATAGATATGATGACTGATGAAG
TAGATGATACTACTATAAATAAAAAACCAGGTTTCTTTAAAGGGTTAATGTCAAAAGGTCTTAATAATGATGATGAAGAA
GATGAATATTTTGAAGAAGAAAATAGTGATGGTGTAGATGATAAAACTATAAAAATAGTTGGATTTAATAAGGCAGAAGA
TGAGTATTTAGAAATATTAGAAGGAACTCAAAGTATGCCAGAGTTAGATGTTTTAAAAGAATTACAAAAAGCTACCAATG
AAAATCCAGTTGTAGATACTAAACCAGAAAAAAAAGTTGATATAGCTAAACCTAATTTAAATATAGAAAAAACTCAACCT
ATGAGTATTGTAGCAGAGCCAGTTAATGAGGATTATTCAAACTATAAAAAGCCTAGCATTGAGCTTTTAAATAAAGTAAA
TAAGAAGTCTGATGAAAATGGTAAAAAGAAAGTGTTGAAAAATGCTTCTCTTTTAGAAAAGACACTATCAGATTTTGGAG
TGGAAGCAAAAATTAATCAAGTTACAGTTGGACCTACTATAACAAGATATGAAATACAACCAAGTCCAGGAGTCAAGGTA
AGTAAAATTGTAAATTTAACTGATGATATAGCTTTAAGTTTAGCAGCTAAAAGTATAAGAATTGAAGCCCCAATTCCTGG
TAAAAGTGCAATTGGAATAGAAGTTCCAAATGAAGAAGCTCAAATGGTTGGTGTGAGAGAAGTTCTAGAAAGTGAAGAAT
TTAATAATTTTAACTCTCCTCTTGCAATGGGACTTGGAAAAGACGTAGCAGGAAAAATTATAATTGGAGATATAGGTAAG
ATGCCACACTTACTAATAGCTGGTTCTACAGGTTCAGGAAAGAGTGTGTGTGTAAATACATTAATAAGTAGTATTTTATA
TAAGGCAAATCCTGATGAAGTAAAATTACTATTAATAGACCCAAAAGTAGTTGAACTTGCAAATTATAATGGAATACCAC
ATCTATTGATACCAGTAGTTACTGACCCTAAAAAAGCTGCAAATGCTTTAAATTGGGCAGTTACAGAGATGAATAGAAGG
TACAAATTATTTGCAGATGCTCAAGTAAAAGATGTAACAAGTTATAATGAGAAAGCGGAAGAAAAACTTCCTAAAATAGT
AATAATAATAGATGAGTTAGCAGATTTAATGATGGCAAGTGCAAATGATGTAGAAGATTATATTTGTAGATTAGCTCAAA
TGGCAAGAGCTGCTGGAATGCACTTGATTGTAGCAACTCAAAGACCATCTGTTGACGTTATAACAGGGGTAATAAAGGCT
AATATACCATCTAGAATAGCATTTGCAGTATCATCTCAAACTGATTCAAGAACAATCCTTGATATGGGTGGTGCAGAGAA
GCTTCTAGGTAAAGGTGATATGTTATTCTATCCACTTGGTGCAGCAAAACCAGTTAGACTTCAAGGGGCATTCATATCAG
AGAGTGAGTCGGAAAAAGTAATCGATTTTGTAAAAAGTCAGGTTAAAGATGGAATAAAATATGAAGAAGATATAATTGAA
ACTATATCTAAGGTTAATACTTCAAAGGGTAGTGATGAGGATGAGTTTTTGAGTGAAGCGATAGAATTTGTCGTGGAAAG
TGGTCAAGCATCTGCCTCTATGCTACAGAGAAGATTTAAAATAGGATTCAATAGAGCAGCTAGACTTATAGATTCTATGG
AAGAAAGAGGAATAATTGGAGCAAGTGAGGGAAGTAAACCGAGAAAGGTATTAATAAGCAAACAGGATTTGCAGAATTTA
GAAGGTGAATAG

Upstream 100 bases:

>100_bases
TATGATATAATGATGTAATAAAGTAGGAGTGTTAGTGTTAAGGCATTAGCACTTTTTGCTGTGAAGGGGTAAAACTTGCT
AAAAATAAGGAGTGATATTA

Downstream 100 bases:

>100_bases
AATTGTCAGTTATAAAAATAGAAAAAGCACTTAAGCTAGATAAAGTAATATTTGTAGATGTGAGAACTGAAGGAGAATAT
GAAGAAGACCATATATTGAA

Product: DNA translocase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 803; Mature: 802

Protein sequence:

>803_residues
MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWIPVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNE
YIYRLRKTKLYYIIILFIFVFYGLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTTINKKPGFFKGLMSKGLNNDDEE
DEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGTQSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQP
MSIVAEPVNEDYSNYKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEIQPSPGVKV
SKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLESEEFNNFNSPLAMGLGKDVAGKIIIGDIGK
MPHLLIAGSTGSGKSVCVNTLISSILYKANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRR
YKLFADAQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIVATQRPSVDVITGVIKA
NIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAAKPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIE
TISKVNTSKGSDEDEFLSEAIEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQNL
EGE

Sequences:

>Translated_803_residues
MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWIPVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNE
YIYRLRKTKLYYIIILFIFVFYGLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTTINKKPGFFKGLMSKGLNNDDEE
DEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGTQSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQP
MSIVAEPVNEDYSNYKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEIQPSPGVKV
SKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLESEEFNNFNSPLAMGLGKDVAGKIIIGDIGK
MPHLLIAGSTGSGKSVCVNTLISSILYKANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRR
YKLFADAQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIVATQRPSVDVITGVIKA
NIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAAKPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIE
TISKVNTSKGSDEDEFLSEAIEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQNL
EGE
>Mature_802_residues
ATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWIPVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEY
IYRLRKTKLYYIIILFIFVFYGLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIFA
LILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTTINKKPGFFKGLMSKGLNNDDEED
EYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGTQSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPM
SIVAEPVNEDYSNYKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEIQPSPGVKVS
KIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLESEEFNNFNSPLAMGLGKDVAGKIIIGDIGKM
PHLLIAGSTGSGKSVCVNTLISSILYKANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRY
KLFADAQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIVATQRPSVDVITGVIKAN
IPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAAKPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIET
ISKVNTSKGSDEDEFLSEAIEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQNLE
GE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=486, Percent_Identity=46.5020576131687, Blast_Score=422, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 88314; Mature: 88183

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWIPVLMQNLFKGLFGGLS
CCCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
IAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFYGLLNAGTLPVDSPLKGNM
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
FDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIFALILSVMFIFNISIKDLVSN
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
AKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTTINKKPGFFKGLMSKGLNNDDEE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCH
DEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGTQSMPELDVLKELQKATNENPVVDT
HHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCC
KPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSNYKKPSIELLNKVNKKSDENGKKKVLK
CCCCCEEEECCCCCCCCCCCHHHEECCCCCHHHHCCCCHHHHHHHHHCCCCCCHHHHHHH
NASLLEKTLSDFGVEAKINQVTVGPTITRYEIQPSPGVKVSKIVNLTDDIALSLAAKSIR
HHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCCCCCCHHHHHCCHHHHHHHHHHHEEE
IEAPIPGKSAIGIEVPNEEAQMVGVREVLESEEFNNFNSPLAMGLGKDVAGKIIIGDIGK
EECCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEEECCCC
MPHLLIAGSTGSGKSVCVNTLISSILYKANPDEVKLLLIDPKVVELANYNGIPHLLIPVV
CCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEHHCCCCCCEEEEEEE
TDPKKAANALNWAVTEMNRRYKLFADAQVKDVTSYNEKAEEKLPKIVIIIDELADLMMAS
CCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHC
ANDVEDYICRLAQMARAAGMHLIVATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTIL
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEE
DMGGAEKLLGKGDMLFYPLGAAKPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIE
ECCCHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
TISKVNTSKGSDEDEFLSEAIEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIG
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
ASEGSKPRKVLISKQDLQNLEGE
CCCCCCCCEEEEEHHHHHCCCCC
>Mature Secondary Structure 
ATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWIPVLMQNLFKGLFGGLS
CCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
IAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFYGLLNAGTLPVDSPLKGNM
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
FDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIFALILSVMFIFNISIKDLVSN
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
AKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTTINKKPGFFKGLMSKGLNNDDEE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCH
DEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGTQSMPELDVLKELQKATNENPVVDT
HHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCC
KPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSNYKKPSIELLNKVNKKSDENGKKKVLK
CCCCCEEEECCCCCCCCCCCHHHEECCCCCHHHHCCCCHHHHHHHHHCCCCCCHHHHHHH
NASLLEKTLSDFGVEAKINQVTVGPTITRYEIQPSPGVKVSKIVNLTDDIALSLAAKSIR
HHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCCCCCCHHHHHCCHHHHHHHHHHHEEE
IEAPIPGKSAIGIEVPNEEAQMVGVREVLESEEFNNFNSPLAMGLGKDVAGKIIIGDIGK
EECCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEEECCCC
MPHLLIAGSTGSGKSVCVNTLISSILYKANPDEVKLLLIDPKVVELANYNGIPHLLIPVV
CCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEHHCCCCCCEEEEEEE
TDPKKAANALNWAVTEMNRRYKLFADAQVKDVTSYNEKAEEKLPKIVIIIDELADLMMAS
CCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHC
ANDVEDYICRLAQMARAAGMHLIVATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTIL
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEE
DMGGAEKLLGKGDMLFYPLGAAKPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIE
ECCCHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
TISKVNTSKGSDEDEFLSEAIEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIG
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
ASEGSKPRKVLISKQDLQNLEGE
CCCCCCCCEEEEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]