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The map label for this gene is rnhB

Identifier: 126698859

GI number: 126698859

Start: 1468065

End: 1468832

Strand: Direct

Name: rnhB

Synonym: CD1262

Alternate gene names: 126698859

Gene position: 1468065-1468832 (Clockwise)

Preceding gene: 126698858

Following gene: 126698860

Centisome position: 34.22

GC content: 30.47

Gene sequence:

>768_bases
ATGCAGGATAAAAGTGTGAGGGAGATTAAAGAAATAATAGAGACTTTAGAAGTAGAAAAATATATGGAATATATAGAGCT
GTTAAGAGTTGATGAAAGAAAATCTGTACAAGGTCTAGCTATAAAACTAGCAAAAAAGCTGGATAATATTAGAAAAGAAG
AAGAAAGATTGGAAACTATAAATATATTTGAGAACGAAGGCTATGATAAAGGTTATTTATATATTGGAGGAATTGATGAG
GCGGGAAGAGGGCCACTTGCTGGACCTGTTGTAGCTTCTGTTGTAGTATTTAAAAAAGATACCAAAATAGAAGGTGTAAA
TGACTCTAAGAAACTGAGTGAGGCAAAAAGAGATGAACTTTTTGAAGTAATAAAAGAAGAAGCACTAGATTATGGAATAG
GTATAGTAAACAATGAAGAAATAGATGAATTTAATATATTAAATGCTACATATATGGCAATGAAAAAGGCTATAAATTGT
TTAAAAAAAGCACCAGATTATTTATTAGTTGATGCAGCAACAATACCAGGTATTGACATATCTCAAAATCCAATTGTGAA
AGGAGATTCAAAATCTATATCAATAGCAGCAGCAAGTATACTTGCTAAAGTTACTAGGGATAGTATAATGTACCAATATG
ATAGAGTATACCCAGAATATGGGTTTAAATCTCACAAAGGATATGGAACTAAAGAACACTATGAAGCTATTGAAAAATAT
GGCATAACTCCTATCCACAGAAAAAGTTTTTTGAAAAATATACTGTAA

Upstream 100 bases:

>100_bases
TGTTTAAAATGTGGCTATAGTGGATGCAATTAAACTCTAATTAAAAAATTTTAATATATTTAAAAATTAAATTTTTAAAA
ACGAAAGATGAGGGAATGGT

Downstream 100 bases:

>100_bases
ATATAATATGATATAATGTATATAATATAAATTACTATAGTTAATGGGGGATTAAAGATGGAATATAATGAATTATTAAA
AAGTGCTAGAGAAAATTTAA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLAKKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDE
AGRGPLAGPVVASVVVFKKDTKIEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYPEYGFKSHKGYGTKEHYEAIEKY
GITPIHRKSFLKNIL

Sequences:

>Translated_255_residues
MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLAKKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDE
AGRGPLAGPVVASVVVFKKDTKIEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYPEYGFKSHKGYGTKEHYEAIEKY
GITPIHRKSFLKNIL
>Mature_255_residues
MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLAKKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDE
AGRGPLAGPVVASVVVFKKDTKIEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYPEYGFKSHKGYGTKEHYEAIEKY
GITPIHRKSFLKNIL

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=176, Percent_Identity=49.4318181818182, Blast_Score=179, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_CLOD6 (Q18BC9)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001087756.1
- ProteinModelPortal:   Q18BC9
- SMR:   Q18BC9
- STRING:   Q18BC9
- GeneID:   4913741
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD1262
- NMPDR:   fig|1496.1.peg.28
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK00015
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 28911; Mature: 28911

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLAKKLDNIRKEEERLETI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTKIEGVNDSKKLSEAKRDEL
HHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHH
FEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINCLKKAPDYLLVDAATIPGIDI
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
SQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYPEYGFKSHKGYGTKEHYEAIEKY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
GITPIHRKSFLKNIL
CCCCHHHHHHHHHCC
>Mature Secondary Structure
MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLAKKLDNIRKEEERLETI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTKIEGVNDSKKLSEAKRDEL
HHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHH
FEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINCLKKAPDYLLVDAATIPGIDI
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
SQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYPEYGFKSHKGYGTKEHYEAIEKY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
GITPIHRKSFLKNIL
CCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA