Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 126698747

GI number: 126698747

Start: 1350569

End: 1351699

Strand: Direct

Name: mrdB [H]

Synonym: CD1152

Alternate gene names: 126698747

Gene position: 1350569-1351699 (Clockwise)

Preceding gene: 126698746

Following gene: 126698748

Centisome position: 31.48

GC content: 32.18

Gene sequence:

>1131_bases
TTGAAAAAAATCAATATTAATTATAAGTCGACAATTAAGTTGATAAAACAGTTAGACTGGAAACTTATAGTTACAGTATT
AGCTATCTTTATTTTTGGGCTTGTTATACTTAGTAGTGCAACACATGCTAATTCAACAGGTTCATATAATCAATTGATTA
AACAAGGATTAGCTTTTGTACTTGGGATAGGAATGATTATAGTCATATTATTTTTTGACTATAACCTTCTAGGCAGGTAT
TATAAAGCGCTTTATATAATAAGTCTTATTTTGTTAGCCATAGTTTTATTACCTGGAATTGGGACAGTAAAAGGTGGAGC
TAGGTCGTGGATTAACTTAGGACCACTTGACTTGCAGACATCTGAAATAGTCAAATTAACATTTGTACTAAGTTATGCAA
AGATACTTGAATCCAAAAAGGATAAATTAAATACGTTAAAGGAAGTTATGCCTGTTGTAGTTTATTCTCTTCCATTTATC
GGATTATTGATTGCACAACCAGACTTGGGAACAGGAATTGTATTTTGTTGTATGATATTTGCAATGCTGTTCACAGCAGG
TCTTAGCTCAAAGTTGATAAAAAGAGGAATAATCATACTATTAGTGTCAATGCCACTGATGTATTTAATGATGGCAGACC
ATCAAAAGGTAAGAATAGAAGCTTTTCTAAATCCAGAAGATGTAACTCTAAAAGGAAACTATCAAGTTATGCAATCTCTG
ATTGCAATTGGTTCTGGAGGCGTAACTGGTAAAGGACTTTACAATGGAAGTCAAAATCAAGAAGATTTTTTACCTGTACA
AGATAGTGATTTTATATTTGCTGTTGTAGGTGAAGAACTTGGTGTAATAGGAATGGCAGTGTTGATAATCTTATTTATGA
TATTCCTATTAAGGCTTTTAGCAATTGCAAGAGATGCAAAAGATTTTTATGGAACCCTCATAGTGGTTGGTGTTATGGGA
ATGTTTGGTTACCAGATAATCCAAAATATAGGTATGACGGTTGCGTTAATACCAGTAACTGGAGTAACATTACCTTTTGT
AAGTTATGGAGGAAGTTCGTTATTGACATCTTTAGCAAACTTAGGATTAGTACTAAATGTGTGTATGAGAAGAAAGAAAA
TAAATTTCTAA

Upstream 100 bases:

>100_bases
AGATAGATGTATGTAATTAGTGCTTAAAAGGGGGATATCCTTATTGGTATATGCCCCTTTTATTTAATTATATGTTTAAA
GATAGAAAGACGGTGATTCT

Downstream 100 bases:

>100_bases
ATTTAAATACATCTAAACATAAATTGAGGAGATTAGATATATGAATATAGCATTAGTAGCACATGACCAAATGAAAAACA
CTATGGTCGGATTTTGTATA

Product: rod shape-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHANSTGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRY
YKALYIISLILLAIVLLPGIGTVKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVRIEAFLNPEDVTLKGNYQVMQSL
IAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVVGEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMG
MFGYQIIQNIGMTVALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF

Sequences:

>Translated_376_residues
MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHANSTGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRY
YKALYIISLILLAIVLLPGIGTVKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVRIEAFLNPEDVTLKGNYQVMQSL
IAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVVGEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMG
MFGYQIIQNIGMTVALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF
>Mature_376_residues
MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHANSTGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRY
YKALYIISLILLAIVLLPGIGTVKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVRIEAFLNPEDVTLKGNYQVMQSL
IAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVVGEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMG
MFGYQIIQNIGMTVALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=318, Percent_Identity=36.4779874213836, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786277, Length=311, Percent_Identity=37.620578778135, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41200; Mature: 41200

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHANSTGSYNQLIKQGLAFV
CCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGTVKGGARSWINLGPLDLQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
SEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFIGLLIAQPDLGTGIVFCCMIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHH
AMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVRIEAFLNPEDVTLKGNYQVMQSL
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEECCCHHHHHHH
IAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVVGEELGVIGMAVLIILFMIFLLRLL
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
AIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTVALIPVTGVTLPFVSYGGSSLLTSLAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCHHHHHHHHH
LGLVLNVCMRRKKINF
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHANSTGSYNQLIKQGLAFV
CCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGTVKGGARSWINLGPLDLQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
SEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFIGLLIAQPDLGTGIVFCCMIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHH
AMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVRIEAFLNPEDVTLKGNYQVMQSL
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEECCCHHHHHHH
IAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVVGEELGVIGMAVLIILFMIFLLRLL
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
AIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTVALIPVTGVTLPFVSYGGSSLLTSLAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCHHHHHHHHH
LGLVLNVCMRRKKINF
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]