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The map label for this gene is mreB2 [H]

Identifier: 126698740

GI number: 126698740

Start: 1343123

End: 1344184

Strand: Direct

Name: mreB2 [H]

Synonym: CD1145

Alternate gene names: 126698740

Gene position: 1343123-1344184 (Clockwise)

Preceding gene: 126698739

Following gene: 126698741

Centisome position: 31.31

GC content: 33.9

Gene sequence:

>1062_bases
ATGGCTAAGGAAAAAAAGAAAGAAAAAAAAGGTTTTTTTAGTTTTAATAAGATGACAAAGGATATGGGAATAGATTTAGG
GACTGCAAATACATTAGTTTACATAAAAGGACAAGGTATTGTTGTTAGAGAACCATCAGTTGTCGCAATAAGAGATGATA
GTAAAGAGGTATTAGCAGTAGGTGAAGAAGCCAAAAAAATGATAGGTAGAACACCAGGAAATATAGTAGCTATAAGACCT
ATGAAAGATGGAGTAATAGCTGATTTTGACATAACTCAATCAATGATTAGCTATTTTATACAAAAAGCGGCTGATAAAAA
AGGTGTTGTAAGTCCAAGAATAGCTATATGTGTTCCTTTTGGAGTTACAGAAGTAGAAAAGAGAGCTATAGAAGAGGCTG
CAAGACAAGCAGGAGCTAAAGATGCATTCCTTATAGAAGAGCCAATGGCAGCGGCTATAGGGGCTGGATTAAAAGTTGAA
GAACCAGAAGGTAATATGGTAGTTGATATTGGTGGAGGTACTTCAGAAATAGCTGTAATATCTTTAGGAGGAATCGTTAC
TGCTAAATCTATAAGAATAGGTGGAGACGAATTTGACGAGTCTATAGTGGCTTATGTAAAAAAAGAATATAATCTTATGA
TAGGTGAAAGAACTGCTGAAAATGTAAAAATTAACATAGGTTCTACATTTAAAGATGATGAAGAAATAAATATGCAAATA
AGAGGTAGAGATTTAATCTCAGGATTACCTAAAACAATAGAAATATGCTCTACAGAAGTTAGAGAAGCATTAAAAGAACC
TGTAAGTTCAATAGTAGATGCAATAAAATCTACACTAGAAAGAACTCCACCAGAATTAGCCTCAGATATAATGGAAAACG
GAATAATGCTAACAGGAGGAGGCGCTTTGCTTAGAGGTCTTGATAAGCTTATTACACAGGAAACTGGTATGTCTGTACAA
ATAGCAGAAACACCTCTTGATTGTGTTGCACTTGGAACAGGTAAATCTGTTGAAGACCAAGAAATCTTTGAAAAAGTATT
AATGATGAATACTAAGAATTAG

Upstream 100 bases:

>100_bases
CTTTAGCTTTAAAGAAAATATGATAATTTGACTTTATATGTGATAAAATAATAGGAGAATGTTTTAAACATGATTCTTAA
TAGTAGGAAGGAGTAAAATC

Downstream 100 bases:

>100_bases
AAGTTGGTGATGGCCTTGAGATTTGACAAGAACAAAAATGAGAAAAAAAGGATTAATGTTAAAGTGATAGCAACGGGCGT
AGTTGCTATCACTTTAATTG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MAKEKKKEKKGFFSFNKMTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVGEEAKKMIGRTPGNIVAIRP
MKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVPFGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVE
EPEGNMVVDIGGGTSEIAVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEEINMQI
RGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMENGIMLTGGGALLRGLDKLITQETGMSVQ
IAETPLDCVALGTGKSVEDQEIFEKVLMMNTKN

Sequences:

>Translated_353_residues
MAKEKKKEKKGFFSFNKMTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVGEEAKKMIGRTPGNIVAIRP
MKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVPFGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVE
EPEGNMVVDIGGGTSEIAVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEEINMQI
RGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMENGIMLTGGGALLRGLDKLITQETGMSVQ
IAETPLDCVALGTGKSVEDQEIFEKVLMMNTKN
>Mature_352_residues
AKEKKKEKKGFFSFNKMTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVGEEAKKMIGRTPGNIVAIRPM
KDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVPFGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEE
PEGNMVVDIGGGTSEIAVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEEINMQIR
GRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMENGIMLTGGGALLRGLDKLITQETGMSVQI
AETPLDCVALGTGKSVEDQEIFEKVLMMNTKN

Specific function: Involved in formation of the rod shape of the cell [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=337, Percent_Identity=57.8635014836795, Blast_Score=390, Evalue=1e-110,
Organism=Escherichia coli, GI1786196, Length=383, Percent_Identity=24.0208877284595, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17507981, Length=383, Percent_Identity=25.5874673629243, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320805, Length=375, Percent_Identity=26.1333333333333, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6320950, Length=240, Percent_Identity=27.5, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319972, Length=392, Percent_Identity=24.4897959183673, Blast_Score=63, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324120, Length=256, Percent_Identity=25.390625, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 38034; Mature: 37902

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEKKKEKKGFFSFNKMTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAV
CCCHHHHHHHCCHHHHHHHHHHCCEECCCCEEEEEECCEEEEECCCEEEEECCCHHHHHC
GEEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVPF
CHHHHHHHCCCCCCEEEEEECCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
GVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEIAVI
CHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCCEEECCCCCEEEEECCCCCEEEEE
SLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEEINMQI
EECCEEEEEEEEECCCHHHHHHHHHHHHHHCEEEECCCCCEEEEEECCCCCCCCCEEEEE
RGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMENGIMLTGG
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECC
GALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNTKN
HHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKEKKKEKKGFFSFNKMTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAV
CCHHHHHHHCCHHHHHHHHHHCCEECCCCEEEEEECCEEEEECCCEEEEECCCHHHHHC
GEEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVPF
CHHHHHHHCCCCCCEEEEEECCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
GVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEIAVI
CHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCCEEECCCCCEEEEECCCCCEEEEE
SLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEEINMQI
EECCEEEEEEEEECCCHHHHHHHHHHHHHHCEEEECCCCCEEEEEECCCCCCCCCEEEEE
RGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMENGIMLTGG
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECC
GALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNTKN
HHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377; 8387996 [H]