Click here to switch to the map view.

The map label for this gene is sorA [H]

Identifier: 126698664

GI number: 126698664

Start: 1269612

End: 1270376

Strand: Direct

Name: sorA [H]

Synonym: CD1077

Alternate gene names: 126698664

Gene position: 1269612-1270376 (Clockwise)

Preceding gene: 126698663

Following gene: 126698665

Centisome position: 29.59

GC content: 33.99

Gene sequence:

>765_bases
ATGAAAATGGAATTTACACAAGTTATTTTGATAACTCTAATTGCATTCTTTGCATATATGCATAGTTTTGTAGGTTCTAC
AATGCATAATAGACCTATAGTTGTTGCACCACTTGTTGGTTTAGCACTAGGTAATCTTCATACAGGTATAGTAATAGGTT
CAACATTAGAATTAGTATTTATGGGTGCATTTCCTGTTGGGGCAAGTAATCCTCCTGATTTTGTGTCTGGTTCTATTATT
GCCACAGCGTTTGTAATATTAACGGGTCAAGATGTATCAGCAGCAGTTGTACTTGCAGTTCCTATAGCAACTCTAGTATT
GCTTATAGATAACTTCTTAATGACAGTAGTACTTACATGGGGAGCTCATATTGCTGACCGTTATGCAGAAGAGGGGAATA
TTGAAGGCGTAGAACGTGTGCAATTATTATTTGGTATAGGAAATAAATTAATATTAGCAATAATAGTAGGTATAGGATTT
TCATTAGGTGTTCCAGTAATAGAAAAAATACTTTCATTTATACCATCATATGTAACTCATGGAATGGATGTTGCAGCAGG
CGTGATTCCAGCAATAGGTTTTGCCATGTTAGCTAGAATGATGCTTAATAAGAAAACAGTAGCATTTTTATTATTAGGAT
TTATATTGGTTGCTTACCTAAACATAACAGTAACAGGAGTTGCATTGTTTGGATTAGCAATAGCTTTAATATATGTTAAC
TTTGTAGGAGAGAAGGAGGTAATAGTAGATGACAACGAGTTCTAA

Upstream 100 bases:

>100_bases
ATGATTAAAGAGTTAGATTCAGAAGGCGTAAATGTATTTGTACAATTAGTTCCTGATGATGATGCTACAAATGTAATGAA
ATTAATATAATTTTAGGGGG

Downstream 100 bases:

>100_bases
GAAATTAGAGACAATTTCACCAGATAGTAAAATAACGAGGAAAGACTTTTGGAAATGTTTTAGAAGGTCATTGACATTAG
ATTCATCTTGGAACTACGAA

Product: PTS system transporter subunit IIC

Products: protein histidine; sugar phosphate; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Sor; PTS system sorbose-specific EIIC component [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKMEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNLHTGIVIGSTLELVFMGAFPVGASNPPDFVSGSII
ATAFVILTGQDVSAAVVLAVPIATLVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGF
SLGVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYLNITVTGVALFGLAIALIYVN
FVGEKEVIVDDNEF

Sequences:

>Translated_254_residues
MKMEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNLHTGIVIGSTLELVFMGAFPVGASNPPDFVSGSII
ATAFVILTGQDVSAAVVLAVPIATLVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGF
SLGVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYLNITVTGVALFGLAIALIYVN
FVGEKEVIVDDNEF
>Mature_254_residues
MKMEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNLHTGIVIGSTLELVFMGAFPVGASNPPDFVSGSII
ATAFVILTGQDVSAAVVLAVPIATLVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGF
SLGVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYLNITVTGVALFGLAIALIYVN
FVGEKEVIVDDNEF

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3715

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1788121, Length=243, Percent_Identity=31.2757201646091, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1789528, Length=193, Percent_Identity=28.4974093264249, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004700
- InterPro:   IPR018404 [H]

Pfam domain/function: PF03609 EII-Sor [H]

EC number: NA

Molecular weight: Translated: 27009; Mature: 27009

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS51106 PTS_EIIC_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCEEEECCCCC
>Mature Secondary Structure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HCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N p -phosphohistidine; sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: protein N p -phosphohistidine + sugar = protein histidine + sugar phosphate phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7947968 [H]