Click here to switch to the map view.

The map label for this gene is frc [H]

Identifier: 126698382

GI number: 126698382

Start: 974669

End: 975907

Strand: Direct

Name: frc [H]

Synonym: CD0802

Alternate gene names: 126698382

Gene position: 974669-975907 (Clockwise)

Preceding gene: 126698381

Following gene: 126698383

Centisome position: 22.72

GC content: 33.66

Gene sequence:

>1239_bases
TTGAAAGTGTTAAATAAACCATTAGAGGGAGTTAAGGTTATTGACCTAACGTATTTTGTAGCAGGTCCAGGGACTTCTAA
AATATTAGCTGACTGGGGTGCTGACGTTATTAAGGTAGAGCCAAGCTTTGGAGACCCAGGAAGAAAGACAGGGGCAACAA
TGACAATGCCAATAGATGATTATAATAATCCTTTTTACAGCACATATAATTCAAATAAAAGAGGTTTGTCTATAAATCTT
AAGAGTGAAACTGGAATTGAAATTATGGATAAGCTTTTAAGCGAAGCAAACGTATTTGTTTCAAGTTATAGAACAGGAGC
ATTAAAAAGACTAGGTCTTGATTATGAATCATTAAGTAAAAAGCATCCACACCTTATCTGGGGTCAGATAAATGGTTTTG
GCGATTTTGGACCTGCTAAGGATAATGCAGGATTTGATACAGTTGCCTTTTGGGCAAGAAGTGGGGCTATGCTTGATATA
GCAGAAAAAGATACAAGTCCAATAAATCCACCTATAGCCTTTGGAGATGCAACAACTTCTTGTAGTTTATCTGGAGGAAT
ATGTGCAGCTTTGTACCAGCAAGCTAAAACTGGAAAAGGACAAAAAGTAATGGCATCTTTATTTGGGCAAGCAATATGGA
ATGCATCATCTTTATTAGCATCTACACAGTTTAGTGATGAGTATCCAAAAACTAGAAAAAATGCTATTTCACCAGTAATA
AATTCTTATCGTTGTAAGGATGGAAAGTGGATATTCTTAAGTATTTTAGAGCATGAAAGATATTTTGAGGCACTTTGTAG
ATTATTTGGAAGAGAAGACTTAATAAAAGAAGAGAAATTTGCATCTTCAGTAGAAAGTAAGAAAAATGCTACAGAACTTA
TTAATATTTTGGATGGTGAATTTGCAAAGTTTACTCAAAATGAGATGGTTGAAAAACTTACTGCTGCTGATATAGCTCAT
GAAAAAATTCAACATGTTAATGATGTAGTGACTGATGAACAGGCTATTGCTAATAACTATATATATGAACATACAAGTAA
AAATGGAAATAAGACAATGCTTGCATCTACTCCAGTTAAATTTGGAAATATTGAAGTTAACATGACTTGTGATGCTCCAC
TTATAGGAGAACATTCAGATGAGATATTGAGAGAACTTGGATACAGTGATTCTGATATAGAAGCTCTAATTGAATCTGGA
ATTGTAACAATGAATAAAGAAGCATGTGAAATATGTTAA

Upstream 100 bases:

>100_bases
TGATATTATAAAATCAATTTTCAAAATATATACAATAAATTTCATGTTTTAATACTGTAAATATGTATTTAAAATAACAA
ATTGACCATATAAGGAGGAA

Downstream 100 bases:

>100_bases
TAAACATGTGAAGTATGTTAATAAATAGGAGGGAATTTTATGGATTTTAGATTAACAGAAGCACAATTAATGCTTCAAAG
AGTAGCAAAAGAATTTGCAG

Product: CoA-transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKVLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDPGRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINL
KSETGIEIMDKLLSEANVFVSSYRTGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDI
AEKDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLASTQFSDEYPKTRKNAISPVI
NSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEEKFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAH
EKIQHVNDVVTDEQAIANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIEALIESG
IVTMNKEACEIC

Sequences:

>Translated_412_residues
MKVLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDPGRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINL
KSETGIEIMDKLLSEANVFVSSYRTGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDI
AEKDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLASTQFSDEYPKTRKNAISPVI
NSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEEKFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAH
EKIQHVNDVVTDEQAIANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIEALIESG
IVTMNKEACEIC
>Mature_412_residues
MKVLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDPGRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINL
KSETGIEIMDKLLSEANVFVSSYRTGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDI
AEKDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLASTQFSDEYPKTRKNAISPVI
NSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEEKFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAH
EKIQHVNDVVTDEQAIANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIEALIESG
IVTMNKEACEIC

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=402, Percent_Identity=30.5970149253731, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI300863124, Length=428, Percent_Identity=28.7383177570093, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI300863126, Length=402, Percent_Identity=27.8606965174129, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI13376042, Length=428, Percent_Identity=25.7009345794392, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI266456254, Length=408, Percent_Identity=26.2254901960784, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI42794625, Length=408, Percent_Identity=26.2254901960784, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI266458393, Length=288, Percent_Identity=27.4305555555556, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI266458397, Length=260, Percent_Identity=28.0769230769231, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI266458395, Length=149, Percent_Identity=29.5302013422819, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI42822893, Length=139, Percent_Identity=29.4964028776978, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788717, Length=417, Percent_Identity=28.0575539568345, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI87082093, Length=385, Percent_Identity=25.974025974026, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1786222, Length=406, Percent_Identity=24.1379310344828, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115535051, Length=343, Percent_Identity=24.198250728863, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32564160, Length=306, Percent_Identity=24.1830065359477, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648431, Length=402, Percent_Identity=29.8507462686567, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24585488, Length=410, Percent_Identity=25.609756097561, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 45315; Mature: 45315

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDPGRKTGATMTMPIDD
CCCCCCCCCCEEEEEEEEEEECCCCCHHHHHCCCCEEEECCCCCCCCCCCCCEEEEECCC
YNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYRTGALKRLGLDYESLSK
CCCCEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
KHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAEKDTSPINPPIAFGDATTS
CCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCEEECCCCCC
CSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLASTQFSDEYPKTRKNAISPVI
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
NSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEEKFASSVESKKNATELINILDGE
HCCCCCCCCEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
FAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAIANNYIYEHTSKNGNKTMLASTPVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEECCCCCCEEEEEECCEE
FGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIEALIESGIVTMNKEACEIC
ECCEEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCEEECCHHHCCC
>Mature Secondary Structure
MKVLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDPGRKTGATMTMPIDD
CCCCCCCCCCEEEEEEEEEEECCCCCHHHHHCCCCEEEECCCCCCCCCCCCCEEEEECCC
YNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYRTGALKRLGLDYESLSK
CCCCEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
KHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAEKDTSPINPPIAFGDATTS
CCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCEEECCCCCC
CSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLASTQFSDEYPKTRKNAISPVI
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
NSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEEKFASSVESKKNATELINILDGE
HCCCCCCCCEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
FAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAIANNYIYEHTSKNGNKTMLASTPVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEECCCCCCEEEEEECCEE
FGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIEALIESGIVTMNKEACEIC
ECCEEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]