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The map label for this gene is mmgC [H]

Identifier: 126698383

GI number: 126698383

Start: 975947

End: 977089

Strand: Direct

Name: mmgC [H]

Synonym: CD0803

Alternate gene names: 126698383

Gene position: 975947-977089 (Clockwise)

Preceding gene: 126698382

Following gene: 126698384

Centisome position: 22.75

GC content: 36.22

Gene sequence:

>1143_bases
ATGGATTTTAGATTAACAGAAGCACAATTAATGCTTCAAAGAGTAGCAAAAGAATTTGCAGAGAATGAAATAGCACCAAT
AGCTGCTGAAACAGACAAAACAGGTATTTTTCCAAGGGAGCTTTTTAGCAAAATGGCTAAAATAGGATTTAATGGAATTG
GAACACCTGTAGAGTATAGTGGTTCTGGTGGGGCAGATATAGAAAAGGTAATTGTTGTTACTGAGATTGCCAAAAAATGT
GCAGCATCTGCAGCAATATTATCAATACACACAATATATGCTCAAGCTATTTTGAAATTTGGTACTGAGGAACAAAAGAA
AAAATACCTTCCAATGATGGCTGAAGGTGGGTGTGTAGGTGCTTTTGCCTTAACCGAACCTAATGCTGGTTCAGATGCTG
CGAGAGCTGCAACAACTGCAATTATTGATGAAGAAACTGATGAATATGTTTTAAATGGAACTAAGTGTTTTATTTCTGGT
GGAGGTCAAGCAGAATCATTAATAATATTTGCACTGACAGACCCATCAAAGGGAATAAAGGGAATGTCTGCTATCATTGT
CGACAAAGGTACTCCAGGTTTTTCAATAGGAAAAATTGAAGAAAAAATGGGTATTCATGGTTCAGAAACTGCAGAGTTAA
TATTTGATAACTGTAGAGTTCCAAAGTCTAACTTATTAGGAAAAGAAGGCAAAGGATTTAATATAGCTATGACTTGTTTA
GATGGAGCAAGAATTGGAGTTGGAGCTCAAGCTGTAGGAATTGCTGAAGGGGCTTTAGAAGAAAGTATCAAATATTCTAA
AGAAAGAGTCCAGTTTGGCAAGCCAATTTCAGCTTTGCAAGGTATTCAATGGTATATAGCAGATATGGCGACAATGGTGG
AATCAGCAAAATTATTAGTATATTATGCTGCAGATTTGAAAGCTAGAGGAGAAAAACACACTAAAGAAGCTGCTATGGCA
AAATACAATGCGTCACGTACTGCAAGAGAGGTTACAAATTTAGCCCTTCAAATCCATGGTGGATATGGATATATGAAGGA
TTATCCATTAGAGAGAATGTACAGAGATGCCAAAATAACAGAAATTTACGAAGGTACTTCAGAAATACACAAAGTTGTTA
TTTCAAGAGCAGTACTAGGATAG

Upstream 100 bases:

>100_bases
AGAAGCTCTAATTGAATCTGGAATTGTAACAATGAATAAAGAAGCATGTGAAATATGTTAATAAACATGTGAAGTATGTT
AATAAATAGGAGGGAATTTT

Downstream 100 bases:

>100_bases
GAGGAAAAGAATGAATATAGTTGTTTGCTTAAAGCAAGTTCCAGATACTAATGAAGTTAAAATAAATAAAGAGACAGGTA
CTCTAATAAGAGATGGTGTA

Product: acyl-CoA dehydrogenase

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSKMAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKC
AASAAILSIHTIYAQAILKFGTEEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNCRVPKSNLLGKEGKGFNIAMTCL
DGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPISALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMA
KYNASRTAREVTNLALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG

Sequences:

>Translated_380_residues
MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSKMAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKC
AASAAILSIHTIYAQAILKFGTEEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNCRVPKSNLLGKEGKGFNIAMTCL
DGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPISALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMA
KYNASRTAREVTNLALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG
>Mature_380_residues
MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSKMAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKC
AASAAILSIHTIYAQAILKFGTEEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNCRVPKSNLLGKEGKGFNIAMTCL
DGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPISALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMA
KYNASRTAREVTNLALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=46.0106382978723, Blast_Score=333, Evalue=1e-91,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=41.0666666666667, Blast_Score=285, Evalue=4e-77,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=38.2978723404255, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI226958412, Length=378, Percent_Identity=36.5079365079365, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=37.467018469657, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=37.467018469657, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI226958414, Length=342, Percent_Identity=36.8421052631579, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI4501857, Length=373, Percent_Identity=35.3887399463807, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI21361497, Length=377, Percent_Identity=35.8090185676393, Blast_Score=211, Evalue=7e-55,
Organism=Homo sapiens, GI76496475, Length=354, Percent_Identity=35.0282485875706, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI4557235, Length=354, Percent_Identity=35.0282485875706, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI4503943, Length=381, Percent_Identity=27.2965879265092, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI7669494, Length=365, Percent_Identity=26.5753424657534, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI38505218, Length=285, Percent_Identity=34.0350877192982, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI211971008, Length=296, Percent_Identity=32.4324324324324, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI48976061, Length=296, Percent_Identity=32.4324324324324, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI218563752, Length=212, Percent_Identity=29.2452830188679, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI156104864, Length=351, Percent_Identity=24.2165242165242, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI156104866, Length=351, Percent_Identity=24.2165242165242, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081958, Length=386, Percent_Identity=32.6424870466321, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=28.9473684210526, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI87081702, Length=299, Percent_Identity=29.4314381270903, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082384, Length=289, Percent_Identity=22.8373702422145, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17506239, Length=383, Percent_Identity=38.6422976501305, Blast_Score=274, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI17508101, Length=376, Percent_Identity=38.8297872340425, Blast_Score=274, Evalue=6e-74,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=39.5287958115183, Blast_Score=269, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17533517, Length=366, Percent_Identity=37.7049180327869, Blast_Score=261, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17569725, Length=388, Percent_Identity=37.6288659793814, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=36.1477572559367, Blast_Score=251, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI17570075, Length=382, Percent_Identity=35.3403141361257, Blast_Score=237, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=45.6834532374101, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI71985184, Length=353, Percent_Identity=37.3937677053824, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17534353, Length=380, Percent_Identity=30, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71985192, Length=299, Percent_Identity=37.123745819398, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=39.2241379310345, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=27.807486631016, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71982178, Length=271, Percent_Identity=34.6863468634686, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=27.9255319148936, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17531909, Length=235, Percent_Identity=32.3404255319149, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17562446, Length=293, Percent_Identity=31.0580204778157, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17531913, Length=179, Percent_Identity=31.8435754189944, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=329, Percent_Identity=24.0121580547112, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI86563383, Length=329, Percent_Identity=24.0121580547112, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=46.0106382978723, Blast_Score=331, Evalue=5e-91,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=43.4666666666667, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=40, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=38.1578947368421, Blast_Score=255, Evalue=3e-68,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=35.2480417754569, Blast_Score=224, Evalue=8e-59,
Organism=Drosophila melanogaster, GI281363737, Length=362, Percent_Identity=35.9116022099448, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI19920834, Length=384, Percent_Identity=29.6875, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI45550141, Length=310, Percent_Identity=26.4516129032258, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221473076, Length=310, Percent_Identity=26.4516129032258, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281365206, Length=333, Percent_Identity=23.7237237237237, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24585193, Length=333, Percent_Identity=23.7237237237237, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24585195, Length=333, Percent_Identity=23.7237237237237, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24585191, Length=333, Percent_Identity=23.7237237237237, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.2

Molecular weight: Translated: 40841; Mature: 40841

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSKMAKIGFNGIGTPVEYS
CCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEC
GSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGTEEQKKKYLPMMAEGGCVG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEECCCEEE
AFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISGGGQAESLIIFALTDPSKGIK
EEEECCCCCCCHHHHHHHHHEECCCCCCEEECCEEEEEECCCCCCEEEEEEEECCCCCCC
GMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNCRVPKSNLLGKEGKGFNIAMTCL
CCEEEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCCHHHCCCCCCCCCEEEEEEE
DGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPISALQGIQWYIADMATMVESAKLLV
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCEEEE
YYAADLKARGEKHTKEAAMAKYNASRTAREVTNLALQIHGGYGYMKDYPLERMYRDAKIT
EEECCHHHCCCHHHHHHHHHHHCHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHCCCHHH
EIYEGTSEIHKVVISRAVLG
HHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSKMAKIGFNGIGTPVEYS
CCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEC
GSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGTEEQKKKYLPMMAEGGCVG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEECCCEEE
AFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISGGGQAESLIIFALTDPSKGIK
EEEECCCCCCCHHHHHHHHHEECCCCCCEEECCEEEEEECCCCCCEEEEEEEECCCCCCC
GMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNCRVPKSNLLGKEGKGFNIAMTCL
CCEEEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCCHHHCCCCCCCCCEEEEEEE
DGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPISALQGIQWYIADMATMVESAKLLV
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCEEEE
YYAADLKARGEKHTKEAAMAKYNASRTAREVTNLALQIHGGYGYMKDYPLERMYRDAKIT
EEECCHHHCCCHHHHHHHHHHHCHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHCCCHHH
EIYEGTSEIHKVVISRAVLG
HHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]