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The map label for this gene is srlE' [H]

Identifier: 126698346

GI number: 126698346

Start: 938092

End: 938658

Strand: Direct

Name: srlE' [H]

Synonym: CD0766

Alternate gene names: 126698346

Gene position: 938092-938658 (Clockwise)

Preceding gene: 126698345

Following gene: 126698347

Centisome position: 21.87

GC content: 36.51

Gene sequence:

>567_bases
ATGGCTTATGATACTAAAAAGAAGATAAGTGAGCAGAGTCAAGGAATTGTTGCAAAAATAGGTATAGCACTAGGAAATGT
GACAAGTACTCTTTTTCAAGCTGGTAGGGATACTATAGATACATTAATACATACTATACTGCCTTTTATGGCTTTCGTTG
CAGTCCTAATAGGTATAATAAATCAATCAGGTATAGGAAATTGGGTAGCCAATTTACTTACTCCATTAATCGGAAATGTT
GGAGGTTTAGTTGTCTTATCAATAATATGTTCATTTCCGTTGTTGTCTCCGTTTCTTGGACCAGGAGCTGTTATAGCTCA
GATAGTGGGAGTATTGGTTGGTACAGAAATAGGAAAAGGAAATATTCCACCAAGTTTAGCATTACCAGCATTGTTTGCAA
TAAACTCACAAGCAGCTTGTGACTTTATACCAGTAGGTCTTGGTCTTGCAGAAGCTGAACCTGATACAGTTCAAGTAGGA
GTTCCGTCAGTTTTATATTCTAGATTTTTAACAGGTGCACCAACTGTTCTATTAGCATGGTTAGCAAGCTTTGGGTTATA
TAAATAG

Upstream 100 bases:

>100_bases
TGGACCATTAGCAATGTTTATAAAAGAAGATATATATGTTTCAGGGGTAAAACCAACAAATGTAGAGCAGTTATAATTGA
GGTAGTAGGAGGGAAGAAAT

Downstream 100 bases:

>100_bases
AAGAATACTTTATAAATAATTAGAGAGAGGTTCAGTTGATATGGAATTAATATACAGTACTCAAATAAATAAAATAGGAG
ATAATGCAAATGAATTTTTA

Product: PTS system glucitol/sorbitol-specific transporter subunit IIC

Products: NA

Alternate protein names: EII-Gut; PTS system glucitol/sorbitol-specific EIIB component [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIHTILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNV
GGLVVLSIICSFPLLSPFLGPGAVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
VPSVLYSRFLTGAPTVLLAWLASFGLYK

Sequences:

>Translated_188_residues
MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIHTILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNV
GGLVVLSIICSFPLLSPFLGPGAVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
VPSVLYSRFLTGAPTVLLAWLASFGLYK
>Mature_187_residues
AYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIHTILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVG
GLVVLSIICSFPLLSPFLGPGAVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVGV
PSVLYSRFLTGAPTVLLAWLASFGLYK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3732

COG function: function code G; Phosphotransferase system sorbitol-specific component IIBC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994905, Length=186, Percent_Identity=69.8924731182796, Blast_Score=265, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011638
- InterPro:   IPR011618
- InterPro:   IPR004702 [H]

Pfam domain/function: PF07663 EIIBC-GUT_C; PF03612 EIIBC-GUT_N [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 19427; Mature: 19296

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS51102 PTS_EIIB_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIHTILPFMAFVAVLIGII
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
NQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPGAVIAQIVGVLVGTEIGKG
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
NIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVGVPSVLYSRFLTGAPTVLLAW
CCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHCCCHHHHHHH
LASFGLYK
HHHHCCCC
>Mature Secondary Structure 
AYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIHTILPFMAFVAVLIGII
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
NQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPGAVIAQIVGVLVGTEIGKG
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
NIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVGVPSVLYSRFLTGAPTVLLAW
CCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHCCCHHHHHHH
LASFGLYK
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3553176; 9205837; 9278503 [H]