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The map label for this gene is srlB [H]

Identifier: 126698347

GI number: 126698347

Start: 938699

End: 939064

Strand: Direct

Name: srlB [H]

Synonym: CD0767

Alternate gene names: 126698347

Gene position: 938699-939064 (Clockwise)

Preceding gene: 126698346

Following gene: 126698348

Centisome position: 21.88

GC content: 26.23

Gene sequence:

>366_bases
ATGGAATTAATATACAGTACTCAAATAAATAAAATAGGAGATAATGCAAATGAATTTTTACAACATAATATGTTTGTAAC
TTTCAAAGATAATGCTCCTCAAGAGTTAGAAAATTACTGTTATATACATTCTGAAAATAATTTAGTAAAAGAAATACTTA
CGGATGATGTGCTATCAATAAATAATGTTGATTACAAAATTACTTCTGTTGGTGAGTTAGTAAACCAAAATCTTTCAGAA
TTAGGTCATATAACATTTAAGTTTACAGGTGAAAAAGATGGAGCAATTGGAGGAACCTTATATCTTGAAGAAAAAGAAAT
AGCACCTATTGGCGTAGGTACTATACTAAAAATAATTAGAAAATAA

Upstream 100 bases:

>100_bases
TTAACAGGTGCACCAACTGTTCTATTAGCATGGTTAGCAAGCTTTGGGTTATATAAATAGAAGAATACTTTATAAATAAT
TAGAGAGAGGTTCAGTTGAT

Downstream 100 bases:

>100_bases
AATTTAAAACGAATCTAATCATATTATAAGTAAATTATAGATAAAAGTCAATTTAACTAATCAAGTTAACTTTTAATGTG
ATAAAAAAGGGGAAATGAAA

Product: PTS system glucitol/sorbitol-specific transporter subunit IIA

Products: Protein Histidine; Sugar Phosphate. [C]

Alternate protein names: EIIA-Gut; EIII-Gut; PTS system glucitol/sorbitol-specific EIIA component [H]

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHSENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSE
LGHITFKFTGEKDGAIGGTLYLEEKEIAPIGVGTILKIIRK

Sequences:

>Translated_121_residues
MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHSENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSE
LGHITFKFTGEKDGAIGGTLYLEEKEIAPIGVGTILKIIRK
>Mature_121_residues
MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHSENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSE
LGHITFKFTGEKDGAIGGTLYLEEKEIAPIGVGTILKIIRK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3731

COG function: function code G; Phosphotransferase system sorbitol-specific component IIA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI1789056, Length=117, Percent_Identity=35.042735042735, Blast_Score=87, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004716
- InterPro:   IPR018454
- ProDom:   PD015842 [H]

Pfam domain/function: PF03829 PTSIIA_gutA [H]

EC number: 2.7.1.69 [C]

Molecular weight: Translated: 13651; Mature: 13651

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS51097 PTS_EIIA_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHSENNLVKEILTDDVLSI
CCEEECCCCCCCCCCHHHHHHCCEEEEECCCCCHHHHCEEEEECCCCHHHHHHHCCCEEC
NNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYLEEKEIAPIGVGTILKIIR
CCCCEEEHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHC
K
C
>Mature Secondary Structure
MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHSENNLVKEILTDDVLSI
CCEEECCCCCCCCCCHHHHHHCCEEEEECCCCCHHHHCEEEEECCCCHHHHHHHCCCEEC
NNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYLEEKEIAPIGVGTILKIIR
CCCCEEEHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Protein N-Phosphohistidine; Sugar [C]

Specific reaction: Protein N-Phosphohistidine + Sugar = Protein Histidine + Sugar Phosphate. [C]

General reaction: Transferases; Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3553176; 1630305; 9205837; 9278503 [H]