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The map label for this gene is srlE [H]

Identifier: 126698345

GI number: 126698345

Start: 937699

End: 938067

Strand: Direct

Name: srlE [H]

Synonym: CD0765

Alternate gene names: 126698345

Gene position: 937699-938067 (Clockwise)

Preceding gene: 126698344

Following gene: 126698346

Centisome position: 21.86

GC content: 33.6

Gene sequence:

>369_bases
ATGGCATTTAACAAAGTTAAAATAGTAAAAGGTTCTGGAGGATGGGGTGGACCATTGATAATAGAACCAACAGAAAAGAA
GAATAAGGTAGTATATGTGACTGGGGGAGCAAAGCCAGAAACTGCAGTAAAAATAGCTGAACTTACAGGATGTGAGTTAA
TAGATGGATTTTCACAGGGTGTTAAAGATGATGAAATCGCATGTGTAATAATAAATTGTGGTGGAACATTGAGATGTGGT
ATATATCCTCAAAAGAAAATACCGACTATAAATATAATGAAAACAGGAAAAAGTGGACCATTAGCAATGTTTATAAAAGA
AGATATATATGTTTCAGGGGTAAAACCAACAAATGTAGAGCAGTTATAA

Upstream 100 bases:

>100_bases
AGGAATAGCATTAAATTCAGATATAAAGATTGGATAATTACTTTAAGGTATAAATAAATTTTTCAAATAAAAAAATAGTG
TATAGAGGAGGATAAATTAT

Downstream 100 bases:

>100_bases
TTGAGGTAGTAGGAGGGAAGAAATATGGCTTATGATACTAAAAAGAAGATAAGTGAGCAGAGTCAAGGAATTGTTGCAAA
AATAGGTATAGCACTAGGAA

Product: PTS system glucitol/sorbitol-specific transporter subunit IIB

Products: NA

Alternate protein names: EII-Gut; PTS system glucitol/sorbitol-specific EIIB component [H]

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVKIAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCG
IYPQKKIPTINIMKTGKSGPLAMFIKEDIYVSGVKPTNVEQL

Sequences:

>Translated_122_residues
MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVKIAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCG
IYPQKKIPTINIMKTGKSGPLAMFIKEDIYVSGVKPTNVEQL
>Mature_121_residues
AFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVKIAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGI
YPQKKIPTINIMKTGKSGPLAMFIKEDIYVSGVKPTNVEQL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3732

COG function: function code G; Phosphotransferase system sorbitol-specific component IIBC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994905, Length=118, Percent_Identity=56.7796610169492, Blast_Score=137, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011638
- InterPro:   IPR011618
- InterPro:   IPR004702 [H]

Pfam domain/function: PF07663 EIIBC-GUT_C; PF03612 EIIBC-GUT_N [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 12998; Mature: 12867

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS51102 PTS_EIIB_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVKIAELTGCELIDGFSQG
CCCCEEEEEECCCCCCCCEEEECCCCCCEEEEEECCCCCCCEEEEEECCCCEEECHHHCC
VKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLAMFIKEDIYVSGVKPTNVE
CCCCCEEEEEECCCCEEEECCCCCCCCCEEEEEECCCCCCEEEEEECCEEEECCCCCCCC
QL
CC
>Mature Secondary Structure 
AFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVKIAELTGCELIDGFSQG
CCCEEEEEECCCCCCCCEEEECCCCCCEEEEEECCCCCCCEEEEEECCCCEEECHHHCC
VKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLAMFIKEDIYVSGVKPTNVE
CCCCCEEEEEECCCCEEEECCCCCCCCCEEEEEECCCCCCEEEEEECCEEEECCCCCCCC
QL
CC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9572925 [H]