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The map label for this gene is gutA [H]

Identifier: 126698344

GI number: 126698344

Start: 937075

End: 937635

Strand: Direct

Name: gutA [H]

Synonym: CD0764

Alternate gene names: 126698344

Gene position: 937075-937635 (Clockwise)

Preceding gene: 126698343

Following gene: 126698345

Centisome position: 21.84

GC content: 31.91

Gene sequence:

>561_bases
ATGACGCAATTTTTTCAAGTATTAGCAAGTGGTGCAGATAGTTTTATGAATTTATTTAGGGCAGGTGGGCAACAATTTGT
AGGTTTTGTAACAGATATAGTACCACTTTTAGTAGCATTATTAGTTACAATGAATGCAATTATCAACTTTATTGGTACAG
ATAGAGTCGAGAGACTTGCAAAAAAATGTTCTGCAAATATATTTACTAGATATTTGATATTACCAGTCCTTGGTACATTT
GTATTTGCAAACCCAATGACACTATCATTAGGAAGATTCTTGCCAGAAAAGTTTAAACCTAGTTACTTTGCAGCAGCAAG
CTTTTCATGCCATACAATGAATGGATTATTCCCACATATCAATCCAGGTGAACTATTTATATATCTAGGAATTGCAAATG
GTATAACAACTTTGGGATTCTCAACAGCAGATTTAGCAGTTAGATATTTGTTAGTGGGTATAGTTGCAAACTTTATTAAA
GGTGTAGTTACTGACTATACAACAAAATTTGTAGAGAAACAACAAGGAATAGCATTAAATTCAGATATAAAGATTGGATA
A

Upstream 100 bases:

>100_bases
TTTGAGAAAAATAAATGTGAAGATACAAATAATCTGAGTACTGATGAAGAGTGTAGGATGGAAGTAGTTTAAAAAAATAT
ATTTATAAGGAGGAGTTAAT

Downstream 100 bases:

>100_bases
TTACTTTAAGGTATAAATAAATTTTTCAAATAAAAAAATAGTGTATAGAGGAGGATAAATTATATGGCATTTAACAAAGT
TAAAATAGTAAAAGGTTCTG

Product: PTS system glucitol/sorbitol-specific transporter subunit IIc2

Products: D-sorbitol 6-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gut; PTS system glucitol/sorbitol-specific EIIC component [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTMNAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTF
VFANPMTLSLGRFLPEKFKPSYFAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
GVVTDYTTKFVEKQQGIALNSDIKIG

Sequences:

>Translated_186_residues
MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTMNAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTF
VFANPMTLSLGRFLPEKFKPSYFAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
GVVTDYTTKFVEKQQGIALNSDIKIG
>Mature_185_residues
TQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTMNAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFV
FANPMTLSLGRFLPEKFKPSYFAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIKG
VVTDYTTKFVEKQQGIALNSDIKIG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3730

COG function: function code G; Phosphotransferase system sorbitol-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994904, Length=180, Percent_Identity=61.6666666666667, Blast_Score=246, Evalue=9e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004699 [H]

Pfam domain/function: PF03608 EII-GUT [H]

EC number: NA

Molecular weight: Translated: 20336; Mature: 20205

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS51107 PTS_EIIC_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTMNAIINFIGTDRVERLA
CHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
KKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSYFAAASFSCHTMNGLFPHI
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHCCCCHHHHCCCCHHHCCCCCCCC
NPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIKGVVTDYTTKFVEKQQGIALN
CCCCEEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEC
SDIKIG
CCCCCC
>Mature Secondary Structure 
TQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTMNAIINFIGTDRVERLA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
KKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSYFAAASFSCHTMNGLFPHI
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHCCCCHHHHCCCCHHHCCCCCCCC
NPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIKGVVTDYTTKFVEKQQGIALN
CCCCEEEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEC
SDIKIG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; sorbitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + sorbitol [Periplasm] = D-sorbitol 6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9435786 [H]