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The map label for this gene is hadB [H]

Identifier: 126697966

GI number: 126697966

Start: 469080

End: 470312

Strand: Direct

Name: hadB [H]

Synonym: CD0397

Alternate gene names: 126697966

Gene position: 469080-470312 (Clockwise)

Preceding gene: 126697965

Following gene: 126697967

Centisome position: 10.93

GC content: 32.2

Gene sequence:

>1233_bases
ATGAAAATGTCTGAAAAAAAAGAAGCTAGAGTAGTAATTAATGATTTATTAGCTGAACAATATGCAAATGCATTTAAAGC
TAAAGAAGAAGGAAGACCTGTAGGTTGGTCAACATCAGTATTTCCTCAAGAGTTAGCAGAAGTATTTGACTTAAACGTAT
TATATCCAGAAAACCAAGCAGCTGGAGTAGCAGCTAAAAAAGGTTCTTTAGAATTATGTGAAATAGCTGAATCTAAAGGA
TATTCTATTGACCTATGTGCATATGCAAGAACAAATTTTGGTCTTTTAGAGAATGGTGGATGTGAAGCTTTGGATATGCC
AGCTCCAGATTTCCTACTTTGCTGTAACAATATATGTAACCAAGTTATAAAATGGTATGAAAATATTTCAAGAGAATTAG
ATATACCTTTAATAATGATTGATACAACTTTCAATAATGAAGACGAAGTTACTCAATCAAGAATAGATTATATTAAAGCT
CAATTTGAAGAAGCTATAAAACAACTAGAAATTATATCAGGAAAGAAATTTGACCCTAAGAAGTTTGAAGAAGTAATGAA
AATATCAGCTGAAAACGGAAGACTATGGAAGTATTCTATGAGTTTACCAGCAGATTCTTCTCCTTCTCCAATGAATGGAT
TTGACTTATTTACTTACATGGCTGTAATAGTTTGTGCTAGAGGTAAAAAAGAAACTACAGAAGCATTTAAGTTACTTATA
GAAGAATTAGAGGACAACATGAAAACTGGTAAATCTTCTTTCAGAGGGGAAGAAAAATACAGAATAATGATGGAAGGTAT
ACCTTGTTGGCCATATATAGGATACAAGATGAAAACATTAGCTAAATTTGGAGTTAACATGACAGGTAGTGTTTATCCAC
ATGCTTGGGCATTACAATATGAAGTTAATGATTTAGATGGAATGGCAGTAGCATATAGTACTATGTTTAACAATGTAAAC
CTAGACCGTATGACAAAATATAGAGTTGATTCTTTAGTAGAGGGTAAATGTGATGGAGCATTCTATCATATGAACAGAAG
CTGTAAACTTATGAGTTTAATACAATATGAAATGCAAAGAAGAGCAGCTGAAGAAACTGGATTACCATATGCTGGATTTG
ATGGTGACCAAGCAGACCCTAGAGCTTTCACTAATGCTCAATTTGAAACAAGAATTCAAGGTTTAGTTGAAGTAATGGAA
GAAAGAAAAAAACTTAATAGAGGTGAGATATAA

Upstream 100 bases:

>100_bases
CTGATATACCTCAATTAACTGGTGCTTTAGGAGCAGCGTTATATGCTTTTGATGAAGCAAAAGAATCACAAAAAGAAGTG
AAAAATATATAAAAAGAGGG

Downstream 100 bases:

>100_bases
TGGAAGCTATTTTATCTAAAATGAAAGAAGTAGTTGAAAATCCAAATGCGGCTGTAAAAAAATATAAAAGTGAAACTGGT
AAAAAAGCTATAGGTTGTTT

Product: subunit of oxygen-sensitive 2-hydroxyisocaproyl-CoA dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKMSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELAEVFDLNVLYPENQAAGVAAKKGSLELCEIAESKG
YSIDLCAYARTNFGLLENGGCEALDMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKA
QFEEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYMAVIVCARGKKETTEAFKLLI
EELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMKTLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVN
LDRMTKYRVDSLVEGKCDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQGLVEVME
ERKKLNRGEI

Sequences:

>Translated_410_residues
MKMSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELAEVFDLNVLYPENQAAGVAAKKGSLELCEIAESKG
YSIDLCAYARTNFGLLENGGCEALDMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKA
QFEEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYMAVIVCARGKKETTEAFKLLI
EELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMKTLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVN
LDRMTKYRVDSLVEGKCDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQGLVEVME
ERKKLNRGEI
>Mature_410_residues
MKMSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELAEVFDLNVLYPENQAAGVAAKKGSLELCEIAESKG
YSIDLCAYARTNFGLLENGGCEALDMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKA
QFEEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYMAVIVCARGKKETTEAFKLLI
EELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMKTLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVN
LDRMTKYRVDSLVEGKCDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQGLVEVME
ERKKLNRGEI

Specific function: Catalyzes the reversible dehydration of 2- hydroxyglutaryl-CoA to glutaconyl-CoA. This is a key step in the fermentation of glutamate. It is activated by hgdC [H]

COG id: COG1775

COG function: function code E; Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010327 [H]

Pfam domain/function: PF06050 HGD-D [H]

EC number: NA

Molecular weight: Translated: 46594; Mature: 46594

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELAEVFDLNVLYPENQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCEEECCCCCC
AGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEALDMPAPDFLLCCNNICN
CCCEECCCCCHHHHHHHCCCCEEEEEEEECCCCCEEECCCCCEECCCCCHHHHHHHHHHH
QVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQFEEAIKQLEIISGKKFDPK
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
KFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYMAVIVCARGKKETTEAFKLLI
HHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMKTLAKFGVNMTGSVYPHAWALQY
HHHHHHHHHCHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEE
EVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGKCDGAFYHMNRSCKLMSLIQYEMQR
ECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHH
RAAEETGLPYAGFDGDQADPRAFTNAQFETRIQGLVEVMEERKKLNRGEI
HHHHHCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKMSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELAEVFDLNVLYPENQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCEEECCCCCC
AGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEALDMPAPDFLLCCNNICN
CCCEECCCCCHHHHHHHCCCCEEEEEEEECCCCCEEECCCCCEECCCCCHHHHHHHHHHH
QVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQFEEAIKQLEIISGKKFDPK
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
KFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYMAVIVCARGKKETTEAFKLLI
HHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMKTLAKFGVNMTGSVYPHAWALQY
HHHHHHHHHCHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEE
EVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGKCDGAFYHMNRSCKLMSLIQYEMQR
ECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHH
RAAEETGLPYAGFDGDQADPRAFTNAQFETRIQGLVEVMEERKKLNRGEI
HHHHHCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2659350; 3691501; 8365476; 11106419 [H]