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The map label for this gene is rbsK [H]

Identifier: 126697871

GI number: 126697871

Start: 360146

End: 361036

Strand: Direct

Name: rbsK [H]

Synonym: CD0299

Alternate gene names: 126697871

Gene position: 360146-361036 (Clockwise)

Preceding gene: 126697870

Following gene: 126697872

Centisome position: 8.39

GC content: 30.86

Gene sequence:

>891_bases
ATGGGAAACATAGTTGTCATAGGAAGTGTAAACATGGACATGGTATGTTCTGTAGATAAAAGACCAGAAAAAGGAGAAAC
AGTATTAGGTAATAGTTTTTTTACATCACCTGGAGGAAAAGGGGCTAATCAAGCTATCTCAGCTTCTAAACTAGGAGCAA
ATGTAAAAATGATATCATGCATAGGGGAAGATGGCTTAGGAGAGGAGTTAATAAGAAATTTTAGAACGAATAAAGTTGAT
TATAGCTTAGTATCCAGAAATAATCACAAAAGTTCTGGTGTTGCTGTTATAACATTATGTGAAAATGATAATAGTATTGT
TGTTGTACCAGGGACTAATGAGCTAGTAGATATAGAATTAATTAAAAAGAATGAAGAAGAGATAAAGAATGCAGATATAG
TATTGCTACAATTAGAGATTCCATTAAAAACAATAAATTATGTAGTGAATTTCTGTTTTGAAAATAGGATTAGGGTTTTA
TTAAATCCAGCACCAGCAGTAAAACTAAATGAAGATATAATAGAAAAAGTAACTTACTTAACACCAAATGAACATGAATA
TAAGATAGTTTTTGACACAAATGAAGGGATAGAAGAAGTATTAAAAAAATATCCAAATAAACTTGTAATAACAGAAGGAA
AAAATGGAGCTAGATTTTATGATGGTGAGGAAATCAAGCATGTATCTTGTATAAGTGTTGATGTTCAAGATACCACAGGA
GCAGGAGATACATTTAATGGAGCATTGGCAGTGGCTATAACAGAAGGGCAAAATTTATATACAGCAGTAGAATATGCAGT
AGTAGTATCAGGTCTTTCTGTAACTAAACTAGGTGCACAATCTGGTATGCCATATAAAGAAGATGTTGAAAAATATTTAA
ATAATAAATAA

Upstream 100 bases:

>100_bases
ATGAATTGATTTTCAAACCAGAATTAGTCATAAGAGATTCAACAAAAGAAAGTGAATAACAGCACGAGAGACATAAATAG
ATATGTAAAGGAGTAATGTA

Downstream 100 bases:

>100_bases
AAATCTAATTTGTTCAAATTTAAAACTATTAAAAATGGAGGTTAATTATGAGAGTGAGAAAAATTTTATCTTTAGGAATT
GCTGGAATACTAGCAATAGG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQAISASKLGANVKMISCIGEDGLGEELIRNFRTNKVD
YSLVSRNNHKSSGVAVITLCENDNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGARFYDGEEIKHVSCISVDVQDTTG
AGDTFNGALAVAITEGQNLYTAVEYAVVVSGLSVTKLGAQSGMPYKEDVEKYLNNK

Sequences:

>Translated_296_residues
MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQAISASKLGANVKMISCIGEDGLGEELIRNFRTNKVD
YSLVSRNNHKSSGVAVITLCENDNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGARFYDGEEIKHVSCISVDVQDTTG
AGDTFNGALAVAITEGQNLYTAVEYAVVVSGLSVTKLGAQSGMPYKEDVEKYLNNK
>Mature_295_residues
GNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQAISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDY
SLVSRNNHKSSGVAVITLCENDNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVLL
NPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGARFYDGEEIKHVSCISVDVQDTTGA
GDTFNGALAVAITEGQNLYTAVEYAVVVSGLSVTKLGAQSGMPYKEDVEKYLNNK

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=31.7567567567568, Blast_Score=136, Evalue=2e-32,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=34.5394736842105, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI87082343, Length=301, Percent_Identity=24.2524916943522, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788484, Length=289, Percent_Identity=22.4913494809689, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081971, Length=273, Percent_Identity=24.9084249084249, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788491, Length=292, Percent_Identity=23.6301369863014, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=290, Percent_Identity=35.1724137931034, Blast_Score=156, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6319884, Length=337, Percent_Identity=31.1572700296736, Blast_Score=119, Evalue=7e-28,
Organism=Drosophila melanogaster, GI20128807, Length=302, Percent_Identity=28.1456953642384, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24583886, Length=310, Percent_Identity=26.7741935483871, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32325; Mature: 32194

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQAISASKLGANVKMISC
CCCEEEEECCCCEEEEECCCCCCCCCEEECCCEECCCCCCCCCHHHHHHHCCCCEEEEEE
IGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCENDNSIVVVPGTNELVDIEL
ECCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEEECCCEEEEEECCCCEEEEEE
IKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVLLNPAPAVKLNEDIIEKVTYL
EECCHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCEEECHHHHHHHHCC
TPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGARFYDGEEIKHVSCISVDVQDTTG
CCCCCEEEEEEECCCCHHHHHHHCCCEEEEEECCCCCEECCCCCCCEEEEEEEEECCCCC
AGDTFNGALAVAITEGQNLYTAVEYAVVVSGLSVTKLGAQSGMPYKEDVEKYLNNK
CCCCCCCEEEEEEECCCCEEHHHEEEHHHCCCEEEEECCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
GNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQAISASKLGANVKMISC
CCEEEEECCCCEEEEECCCCCCCCCEEECCCEECCCCCCCCCHHHHHHHCCCCEEEEEE
IGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCENDNSIVVVPGTNELVDIEL
ECCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEEECCCEEEEEECCCCEEEEEE
IKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVLLNPAPAVKLNEDIIEKVTYL
EECCHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCEEECHHHHHHHHCC
TPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGARFYDGEEIKHVSCISVDVQDTTG
CCCCCEEEEEEECCCCHHHHHHHCCCEEEEEECCCCCEECCCCCCCEEEEEEEEECCCCC
AGDTFNGALAVAITEGQNLYTAVEYAVVVSGLSVTKLGAQSGMPYKEDVEKYLNNK
CCCCCCCEEEEEEECCCCEEHHHEEEHHHCCCEEEEECCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]