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The map label for this gene is fabZ

Identifier: 126697700

GI number: 126697700

Start: 172910

End: 173338

Strand: Direct

Name: fabZ

Synonym: CD0128

Alternate gene names: 126697700

Gene position: 172910-173338 (Clockwise)

Preceding gene: 126697699

Following gene: 126697702

Centisome position: 4.03

GC content: 32.87

Gene sequence:

>429_bases
ATGTTAAATATAGATGAAATAAAAAAATTAATACCACATAGATATCCATTTTTATTAGTAGACAAGATTACAGAGCTAGA
AGTTGGGAAAAGAGCTGTTGGTATAAAGAATGTAACAGTTAATGAACCATTTTTCCAAGGTCACTTTCCAGAATATCCTT
TGATGCCAGGAGTACTAATAGTAGAAGCTCTAGCACAAGTATGTGGAGTGGCAATGATGTCTGTAGAGGAAAACAAAGGA
AAACTAGGTGTATTTGCAGGTATAGATAAAGTTAGAATCAAGAGAGAAGTAAGACCAGGAGATACATTAACTATGGAAGT
TGAAATGACAACTCTTAGAAAAAATATAGCTAAGGCAGATGCTAAGGCATATGTAGGTGAAGAACTTGTCTGTAAAGGTG
AATTAATGTTTGCTTTAGTAGAAAAATAA

Upstream 100 bases:

>100_bases
ATTATCTTGTGTTGCAAAAGGTACAGGAATAGCTTTAGGTTCAATAGACTTACTTGAAACTGGTGGGTCTTTCAAAAGAA
AATAATTAGGAGAGTTTAGA

Downstream 100 bases:

>100_bases
AAACTTGAAATATAAAAGTAAAAAGGTAGATAATTTGGAGTATTTAATCAGATACTCTAAAATATCTACCTTTTTATATA
AAGAATTTTATCATTTAGTT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPFFQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKG
KLGVFAGIDKVRIKREVRPGDTLTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK

Sequences:

>Translated_142_residues
MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPFFQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKG
KLGVFAGIDKVRIKREVRPGDTLTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK
>Mature_142_residues
MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPFFQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKG
KLGVFAGIDKVRIKREVRPGDTLTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=48.9208633093525, Blast_Score=133, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_CLOD6 (Q18CL9)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001086597.1
- ProteinModelPortal:   Q18CL9
- SMR:   Q18CL9
- STRING:   Q18CL9
- GeneID:   4913805
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD0128
- NMPDR:   fig|1496.1.peg.1538
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KASARAC
- ProtClustDB:   PRK00006
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 15860; Mature: 15860

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPFFQGHFPEYPLMPGVLI
CCCHHHHHHHCCCCCCEEEEHHHHHHHCCCHHCCEEEEEECCCCCCCCCCCCCCCCHHHH
VEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDTLTMEVEMTTLRKNIAKAD
HHHHHHHHHHHHHHEECCCCCEEEEECCHHHHEEECCCCCCEEEEEEEHHHHHHHHHHHH
AKAYVGEELVCKGELMFALVEK
HHHHCCCHHEECCCEEEEEECC
>Mature Secondary Structure
MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPFFQGHFPEYPLMPGVLI
CCCHHHHHHHCCCCCCEEEEHHHHHHHCCCHHCCEEEEEECCCCCCCCCCCCCCCCHHHH
VEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDTLTMEVEMTTLRKNIAKAD
HHHHHHHHHHHHHHEECCCCCEEEEECCHHHHEEECCCCCCEEEEEEEHHHHHHHHHHHH
AKAYVGEELVCKGELMFALVEK
HHHHCCCHHEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA