| Definition | Burkholderia mallei NCTC 10247 chromosome II, complete genome. |
|---|---|
| Accession | NC_009079 |
| Length | 2,352,693 |
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The map label for this gene is linX [H]
Identifier: 126446626
GI number: 126446626
Start: 245050
End: 245829
Strand: Direct
Name: linX [H]
Synonym: BMA10247_A0283
Alternate gene names: 126446626
Gene position: 245050-245829 (Clockwise)
Preceding gene: 126445594
Following gene: 126446587
Centisome position: 10.42
GC content: 71.41
Gene sequence:
>780_bases TTGGCGCCGCGCCTGGCCGGCAAGCGCGCGTTCATCACCGGCGCTGCGGGCGGCCTCGGGCGCGCGATCGCGCGCCGGAT GGCCGAGCAGGGCGCGCAGGTGTTCTTGACCGACATCGTCGACGCGGCCGTGCTCGAGGCGTTCGCGGCCGAGCTCAACG ATACGGCCGGCGAGCGCATTGCGTGGGCGGCCGTGCAGGACGTCGCCGACGAAGCGCAGTGGGCGTCGCGCCTTTCGCAG GCGGCAGACGCGATGGGCGGGCTGTCGGTGCTCGTGCACAACGCGGGCGTCGGCTCGTTCGGCGCGATCGGGCAGATCGC GCGCGACGAGTGGCGGCGCGTGATGGCGATCAACGTCGAGAGCATCGTGCTCGGCACGAAGCATGCGCTGCCGTATCTGG AGGCGGGCGCGCCCGCGTCGATCGTCAATATCTCGTCGGTCGCCGCGTTCAAGCAGGAGCCCGACTACACCGCGTACAAC GCGTCGAAGGCGGCGGTCGCGTCGCTCACGAAGTCGATCGCGGTGGATTGCGCGCGCCGGCAGACGGAGGTGCGCTGCAA CTCGATCCATCCGTCGTTCATCATGACGGGCATCGTCGCGCCGATCGTCCGGCTGGTCGGCGAGAAGGAAGCCGCGCGCA AGCTCGCGCGCGGCGTGCCGATGCGCCGGCTCGGCGAGCCCGACGACGTCGCGCATGCGGCCGTCTATCTCGCGTCCGAC GAGAGCCGCTACGTGACGGGCGCGGAGCTCGTGATCGACGGCGGGATGTGCGCGGTCTGA
Upstream 100 bases:
>100_bases CCGCTCGAGCGCATGACGCTTCGGGCGCACGAGCGAAGCGCGCGGGCGGCGAGCGAACATCGAAAACGACAGGGGAGTGT TCATGACGAAGACGAAGCAT
Downstream 100 bases:
>100_bases CGTCGCGCGTGCGTCGGCGGCGGCATTTTCGCGCGCCGCCGGCGAAACTTGAAAAATCGCGGCGGTGTGATTGCATCGTT GCGGATCGCGGATCGCGGAT
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 2,5-DDOL dehydrogenase [H]
Number of amino acids: Translated: 259; Mature: 258
Protein sequence:
>259_residues MAPRLAGKRAFITGAAGGLGRAIARRMAEQGAQVFLTDIVDAAVLEAFAAELNDTAGERIAWAAVQDVADEAQWASRLSQ AADAMGGLSVLVHNAGVGSFGAIGQIARDEWRRVMAINVESIVLGTKHALPYLEAGAPASIVNISSVAAFKQEPDYTAYN ASKAAVASLTKSIAVDCARRQTEVRCNSIHPSFIMTGIVAPIVRLVGEKEAARKLARGVPMRRLGEPDDVAHAAVYLASD ESRYVTGAELVIDGGMCAV
Sequences:
>Translated_259_residues MAPRLAGKRAFITGAAGGLGRAIARRMAEQGAQVFLTDIVDAAVLEAFAAELNDTAGERIAWAAVQDVADEAQWASRLSQ AADAMGGLSVLVHNAGVGSFGAIGQIARDEWRRVMAINVESIVLGTKHALPYLEAGAPASIVNISSVAAFKQEPDYTAYN ASKAAVASLTKSIAVDCARRQTEVRCNSIHPSFIMTGIVAPIVRLVGEKEAARKLARGVPMRRLGEPDDVAHAAVYLASD ESRYVTGAELVIDGGMCAV >Mature_258_residues APRLAGKRAFITGAAGGLGRAIARRMAEQGAQVFLTDIVDAAVLEAFAAELNDTAGERIAWAAVQDVADEAQWASRLSQA ADAMGGLSVLVHNAGVGSFGAIGQIARDEWRRVMAINVESIVLGTKHALPYLEAGAPASIVNISSVAAFKQEPDYTAYNA SKAAVASLTKSIAVDCARRQTEVRCNSIHPSFIMTGIVAPIVRLVGEKEAARKLARGVPMRRLGEPDDVAHAAVYLASDE SRYVTGAELVIDGGMCAV
Specific function: Catalyzes the degradation of 2,5-dichloro-2,5- cyclohexadiene-1,4-diol (2,5-DDOL) into 2,5-dichlorohydroquinone (2,5-DCHQ). LinX appears not to be involved in gamma-HCH degradation pathway [H]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=34.3873517786561, Blast_Score=133, Evalue=1e-31, Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=34.3629343629344, Blast_Score=115, Evalue=3e-26, Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=30.3501945525292, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=35.0393700787402, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=29.3877551020408, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=29.3650793650794, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=32.6086956521739, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=31.8627450980392, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI7705925, Length=255, Percent_Identity=25.0980392156863, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=31.9587628865979, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI224922801, Length=179, Percent_Identity=32.4022346368715, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI59889578, Length=191, Percent_Identity=31.413612565445, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI302344755, Length=102, Percent_Identity=36.2745098039216, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=28.2868525896414, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=26.1363636363636, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI4758504, Length=265, Percent_Identity=29.4339622641509, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI40254986, Length=167, Percent_Identity=32.3353293413174, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI109715829, Length=242, Percent_Identity=25.6198347107438, Blast_Score=69, Evalue=3e-12, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=38.671875, Blast_Score=143, Evalue=9e-36, Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=32.1428571428571, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=29.7297297297297, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=31.6205533596838, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=31.0483870967742, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=29.5019157088123, Blast_Score=97, Evalue=9e-22, Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=29.2490118577075, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=29.0836653386454, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=27.4900398406374, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=29.4117647058824, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI2367365, Length=258, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=32.156862745098, Blast_Score=120, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=34.375, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI25147288, Length=265, Percent_Identity=31.3207547169811, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=32.3420074349442, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=28.8888888888889, Blast_Score=107, Evalue=8e-24, Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=30.2325581395349, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=32.3308270676692, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=30.2325581395349, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=32.1033210332103, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17538480, Length=275, Percent_Identity=29.4545454545455, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=30.9963099630996, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=30.1470588235294, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=30.7407407407407, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=29.9625468164794, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI72000259, Length=274, Percent_Identity=30.6569343065693, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17563726, Length=274, Percent_Identity=31.021897810219, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17551412, Length=272, Percent_Identity=29.0441176470588, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=29.2490118577075, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=29.1666666666667, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17562990, Length=272, Percent_Identity=28.3088235294118, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=30.4347826086957, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=27.6515151515151, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560150, Length=272, Percent_Identity=26.8382352941176, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=26.8382352941176, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=27.9527559055118, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=25.830258302583, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17567345, Length=194, Percent_Identity=24.2268041237113, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI71982365, Length=148, Percent_Identity=28.3783783783784, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17558628, Length=147, Percent_Identity=31.9727891156463, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=258, Percent_Identity=29.4573643410853, Blast_Score=77, Evalue=3e-15, Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=26.3779527559055, Blast_Score=71, Evalue=2e-13, Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=33.984375, Blast_Score=110, Evalue=8e-25, Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=34.8659003831418, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI21355319, Length=261, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI21357041, Length=269, Percent_Identity=33.0855018587361, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24643142, Length=265, Percent_Identity=29.0566037735849, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI17737361, Length=263, Percent_Identity=33.0798479087452, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=32.03125, Blast_Score=92, Evalue=2e-19, Organism=Drosophila melanogaster, GI24639444, Length=261, Percent_Identity=30.2681992337165, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644337, Length=178, Percent_Identity=35.9550561797753, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI161076933, Length=195, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI24584748, Length=195, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=25.7575757575758, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI21357673, Length=262, Percent_Identity=29.0076335877863, Blast_Score=68, Evalue=8e-12, Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=25.7575757575758, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI18859837, Length=192, Percent_Identity=27.6041666666667, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI221331218, Length=193, Percent_Identity=25.3886010362694, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI24665243, Length=193, Percent_Identity=25.3886010362694, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 27145; Mature: 27014
Theoretical pI: Translated: 6.52; Mature: 6.52
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAPRLAGKRAFITGAAGGLGRAIARRMAEQGAQVFLTDIVDAAVLEAFAAELNDTAGERI CCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH AWAAVQDVADEAQWASRLSQAADAMGGLSVLVHNAGVGSFGAIGQIARDEWRRVMAINVE HHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHEECHH SIVLGTKHALPYLEAGAPASIVNISSVAAFKQEPDYTAYNASKAAVASLTKSIAVDCARR HHEECCHHCCCCCCCCCCCHHEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH QTEVRCNSIHPSFIMTGIVAPIVRLVGEKEAARKLARGVPMRRLGEPDDVAHAAVYLASD HHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCCCHHHHHEEEEECC ESRYVTGAELVIDGGMCAV CCCEEECCEEEECCCCCCC >Mature Secondary Structure APRLAGKRAFITGAAGGLGRAIARRMAEQGAQVFLTDIVDAAVLEAFAAELNDTAGERI CCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH AWAAVQDVADEAQWASRLSQAADAMGGLSVLVHNAGVGSFGAIGQIARDEWRRVMAINVE HHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHEECHH SIVLGTKHALPYLEAGAPASIVNISSVAAFKQEPDYTAYNASKAAVASLTKSIAVDCARR HHEECCHHCCCCCCCCCCCHHEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH QTEVRCNSIHPSFIMTGIVAPIVRLVGEKEAARKLARGVPMRRLGEPDDVAHAAVYLASD HHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCCCHHHHHEEEEECC ESRYVTGAELVIDGGMCAV CCCEEECCEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7515041; 12450824 [H]