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The map label for this gene is lysN [H]

Identifier: 126455457

GI number: 126455457

Start: 1142932

End: 1144113

Strand: Reverse

Name: lysN [H]

Synonym: BURPS1106A_1163

Alternate gene names: 126455457

Gene position: 1144113-1142932 (Counterclockwise)

Preceding gene: 126452292

Following gene: 126454512

Centisome position: 28.69

GC content: 69.04

Gene sequence:

>1182_bases
ATGAATCCGAGCGATCTCAAGCCGCCCCGCTGGGCCCTGTCCGAACGCGCACGCAAGCTCACGAGCTCGGCGATCCGCGA
AATCCTGAAAGTGACCGAGCGCCCCGAGGTGATCTCGTTCGCGGGCGGCCTGCCCTCGCCCGCGACGTTCCCCGCCGAGC
GCATGCGCGAGGCCGCGGAGCGCGTGCTGCGCGATTCGCCCGCCGCCGCGCTGCAATACAGCGCGACGGAAGGCTTCCTG
CCGCTGCGCGAGTGGATTGCCGAGCGCTACCGCGTGCGCACGACGCAGGTGCTCGTCACGACGGGCTCGCAGCAGGCGCT
CGATCTGCTCGGCAAGGTGCTGATCGATCCGGCGAGCCGCGTGCTCGTGGAGACGCCGACCTACCTCGGCGCGCTGCAGT
CGTTCTCGCTGTACGAGCCGATCTACGCGCAGGTGCCGACCGACGACGCGGGCCTGCTGCCCGAAGCGCTCACGCCCGAG
CTGACGAAGGACGCGCGATTGTTGTATGCGCAACCGAACTTCCAGAACCCGACGGGCCGCCGCCTGAGCGTCGAGCGCCG
CCGCGCGCTCGCCGCCTTCGCGCGGACGAGCCCGTTCCCGGTGCTCGAGGACGATCCGTACGGCGCGCTGAACTACGCGG
GCGAGCCGCTGCCGACGATGCTGTCGATGGCGCCCGATCACATCGTCCATCTCGGCACGTTCTCGAAGGTGCTCGCACCC
GGCCTGCGGATCGGCTATATCATTGCGCCCGAGGAGCTGCACTTCAAGCTCGTGCAGGCCAAGCAGGCGACCGACCTGCA
CACGCCGTCGCTCACGCAGCGCATCGCCCACGAAGTCATCCAGGACGGCTTCCTCGATGCGCACATCCCGACGATCCGCA
AGCTCTACGGCGCGCAGTGCGAAGCGATGCTCGCGTCGCTCGCGCGGCACATGCCGCAAGGCGTGAGCTGGAACCGCCCG
GAAGGCGGGATGTTCATCTGGGTGACGCTGCCCGCGCAGATCGACAGCATGCAGCTCCTCGAGACGGCGGTCGCGAACAA
CGTCGCGTTCGTGCCGGGCGCGCCGTTCTTCGCGAACGACGCGCAGAAGAACACGCTGCGGCTGTCGTTCGTCACCGTGC
CGCCGGAGAAGATCGAGGAAGGCGTCGCGCGGCTCGGCAAGCTGTTGCGCGAGCGCCTGTGA

Upstream 100 bases:

>100_bases
CGCCGTGGGCGCCGCGCCGCATCCGGCTCGCGCCGCCTGATTTGACGAGCGATAATCGACGCTTTCATCCGCACGCCCCA
TGACACCGACCGAGGAGACC

Downstream 100 bases:

>100_bases
CGCGCCTCGTTCGCTCACGCATTCACGATTGACTCACTCACGAACTCACGAGGATATGAATCAGATGGCAAACGTCTACG
ACAAACTGAAGGAACTCGGC

Product: aminotransferase, class I/II

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MNPSDLKPPRWALSERARKLTSSAIREILKVTERPEVISFAGGLPSPATFPAERMREAAERVLRDSPAAALQYSATEGFL
PLREWIAERYRVRTTQVLVTTGSQQALDLLGKVLIDPASRVLVETPTYLGALQSFSLYEPIYAQVPTDDAGLLPEALTPE
LTKDARLLYAQPNFQNPTGRRLSVERRRALAAFARTSPFPVLEDDPYGALNYAGEPLPTMLSMAPDHIVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPSLTQRIAHEVIQDGFLDAHIPTIRKLYGAQCEAMLASLARHMPQGVSWNRP
EGGMFIWVTLPAQIDSMQLLETAVANNVAFVPGAPFFANDAQKNTLRLSFVTVPPEKIEEGVARLGKLLRERL

Sequences:

>Translated_393_residues
MNPSDLKPPRWALSERARKLTSSAIREILKVTERPEVISFAGGLPSPATFPAERMREAAERVLRDSPAAALQYSATEGFL
PLREWIAERYRVRTTQVLVTTGSQQALDLLGKVLIDPASRVLVETPTYLGALQSFSLYEPIYAQVPTDDAGLLPEALTPE
LTKDARLLYAQPNFQNPTGRRLSVERRRALAAFARTSPFPVLEDDPYGALNYAGEPLPTMLSMAPDHIVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPSLTQRIAHEVIQDGFLDAHIPTIRKLYGAQCEAMLASLARHMPQGVSWNRP
EGGMFIWVTLPAQIDSMQLLETAVANNVAFVPGAPFFANDAQKNTLRLSFVTVPPEKIEEGVARLGKLLRERL
>Mature_393_residues
MNPSDLKPPRWALSERARKLTSSAIREILKVTERPEVISFAGGLPSPATFPAERMREAAERVLRDSPAAALQYSATEGFL
PLREWIAERYRVRTTQVLVTTGSQQALDLLGKVLIDPASRVLVETPTYLGALQSFSLYEPIYAQVPTDDAGLLPEALTPE
LTKDARLLYAQPNFQNPTGRRLSVERRRALAAFARTSPFPVLEDDPYGALNYAGEPLPTMLSMAPDHIVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPSLTQRIAHEVIQDGFLDAHIPTIRKLYGAQCEAMLASLARHMPQGVSWNRP
EGGMFIWVTLPAQIDSMQLLETAVANNVAFVPGAPFFANDAQKNTLRLSFVTVPPEKIEEGVARLGKLLRERL

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=414, Percent_Identity=30.4347826086957, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI33469970, Length=414, Percent_Identity=30.4347826086957, Blast_Score=185, Evalue=6e-47,
Organism=Escherichia coli, GI1787710, Length=381, Percent_Identity=27.8215223097113, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1790797, Length=338, Percent_Identity=28.698224852071, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI48994949, Length=227, Percent_Identity=27.3127753303965, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321236, Length=489, Percent_Identity=23.3128834355828, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321000, Length=431, Percent_Identity=25.9860788863109, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356535, Length=395, Percent_Identity=27.3417721518987, Blast_Score=131, Evalue=7e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 43444; Mature: 43444

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPSDLKPPRWALSERARKLTSSAIREILKVTERPEVISFAGGLPSPATFPAERMREAAE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
RVLRDSPAAALQYSATEGFLPLREWIAERYRVRTTQVLVTTGSQQALDLLGKVLIDPASR
HHHHCCCCHHEEECCCCCCHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHCCCHH
VLVETPTYLGALQSFSLYEPIYAQVPTDDAGLLPEALTPELTKDARLLYAQPNFQNPTGR
HEEECCHHHHHHHHHHHCCCHHEECCCCCCCCCCHHCCCCCCCCCEEEEECCCCCCCCCC
RLSVERRRALAAFARTSPFPVLEDDPYGALNYAGEPLPTMLSMAPDHIVHLGTFSKVLAP
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHEEEHHHHHHHHCC
GLRIGYIIAPEELHFKLVQAKQATDLHTPSLTQRIAHEVIQDGFLDAHIPTIRKLYGAQC
CCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
EAMLASLARHMPQGVSWNRPEGGMFIWVTLPAQIDSMQLLETAVANNVAFVPGAPFFAND
HHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCEEECCCCCCCCCC
AQKNTLRLSFVTVPPEKIEEGVARLGKLLRERL
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPSDLKPPRWALSERARKLTSSAIREILKVTERPEVISFAGGLPSPATFPAERMREAAE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
RVLRDSPAAALQYSATEGFLPLREWIAERYRVRTTQVLVTTGSQQALDLLGKVLIDPASR
HHHHCCCCHHEEECCCCCCHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHCCCHH
VLVETPTYLGALQSFSLYEPIYAQVPTDDAGLLPEALTPELTKDARLLYAQPNFQNPTGR
HEEECCHHHHHHHHHHHCCCHHEECCCCCCCCCCHHCCCCCCCCCEEEEECCCCCCCCCC
RLSVERRRALAAFARTSPFPVLEDDPYGALNYAGEPLPTMLSMAPDHIVHLGTFSKVLAP
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHEEEHHHHHHHHCC
GLRIGYIIAPEELHFKLVQAKQATDLHTPSLTQRIAHEVIQDGFLDAHIPTIRKLYGAQC
CCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
EAMLASLARHMPQGVSWNRPEGGMFIWVTLPAQIDSMQLLETAVANNVAFVPGAPFFAND
HHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCEEECCCCCCCCCC
AQKNTLRLSFVTVPPEKIEEGVARLGKLLRERL
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA