Click here to switch to the map view.

The map label for this gene is surE

Identifier: 126209387

GI number: 126209387

Start: 2164002

End: 2164766

Strand: Direct

Name: surE

Synonym: APL_1927

Alternate gene names: 126209387

Gene position: 2164002-2164766 (Clockwise)

Preceding gene: 126209386

Following gene: 126209388

Centisome position: 95.14

GC content: 46.67

Gene sequence:

>765_bases
ATGAATATCTTAATCAGTAATGATGACGGCTATCACGCACAGGGCATTCAAACACTTGCCGAAACGTTGCGCGATGCAGG
ACATTCGGTGACGGTAATTGCGCCGGATCGCAATCGCAGTGCCGCATCAAGTTGTTTAACTTTGATGGAACCGATTCGTG
TACATCAACTTGACGAATTTAATTATGCGGTGATTGCCGGTACGCCGGCGGATTGCGTACACTTAGCCCTTAACGGCTTT
TTTGAGCAATCATTCGATTTAGTTATTTCGGGGATTAACCACGGTGCCAATTTAGGTGATGATGTGGTTTATTCGGGAAC
GGTTGCCGCGGCTTTGGAAGGCCGTCATTTACCTTATCCAAGTTTAGCGATTTCGCTGGTGGGTAGAAAATCCGAAGGAC
ATTTATTCGGTAATAACCATTTTGATACGGCGGCTAAAGTGGTCTTGGATTTATTGCCGAAAGTACAAAAAGGCATTGTA
CCTGCCCGTCAGATTTTAAATATTAATGTGCCGGATCTACCTTACGAACAAGTCAAAGGCGTGATGATTACCCGTTTAGG
GCATCGTTCGCCGGCAGCGGAAATCGTTAAACGAGAAGATCCTCGCGGCGCAACGATTTATTGGCTGGGGGCGAACGGCG
TGCCGGTAGATGCGAGTGAAGGTACCGATTTTTATGCGTTGGCACATAACTATGTCTCCGTTACGCCGATTCAGGCGGAT
ATGACGGCGCACTATTCCATTCAAGCTCTTAAGGATACTTTTTAA

Upstream 100 bases:

>100_bases
GATTTGAAGCCGAGGGCTTACGACTTCGTTTCTTTTTAGATTCGGGAAGCTATGCTACCGCATTAGTGCGAGAATTAATT
CAATTAACGGAACAAGAATA

Downstream 100 bases:

>100_bases
TGAAATTATTTGGTCCGATTTATGATAAAACGATGGAATGGTCTAAACACCGTTTTGCCGGTTTTTGGTTGAGTTTCGTG
AGTTTTATCGAGGCGATTTT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MNILISNDDGYHAQGIQTLAETLRDAGHSVTVIAPDRNRSAASSCLTLMEPIRVHQLDEFNYAVIAGTPADCVHLALNGF
FEQSFDLVISGINHGANLGDDVVYSGTVAAALEGRHLPYPSLAISLVGRKSEGHLFGNNHFDTAAKVVLDLLPKVQKGIV
PARQILNINVPDLPYEQVKGVMITRLGHRSPAAEIVKREDPRGATIYWLGANGVPVDASEGTDFYALAHNYVSVTPIQAD
MTAHYSIQALKDTF

Sequences:

>Translated_254_residues
MNILISNDDGYHAQGIQTLAETLRDAGHSVTVIAPDRNRSAASSCLTLMEPIRVHQLDEFNYAVIAGTPADCVHLALNGF
FEQSFDLVISGINHGANLGDDVVYSGTVAAALEGRHLPYPSLAISLVGRKSEGHLFGNNHFDTAAKVVLDLLPKVQKGIV
PARQILNINVPDLPYEQVKGVMITRLGHRSPAAEIVKREDPRGATIYWLGANGVPVDASEGTDFYALAHNYVSVTPIQAD
MTAHYSIQALKDTF
>Mature_254_residues
MNILISNDDGYHAQGIQTLAETLRDAGHSVTVIAPDRNRSAASSCLTLMEPIRVHQLDEFNYAVIAGTPADCVHLALNGF
FEQSFDLVISGINHGANLGDDVVYSGTVAAALEGRHLPYPSLAISLVGRKSEGHLFGNNHFDTAAKVVLDLLPKVQKGIV
PARQILNINVPDLPYEQVKGVMITRLGHRSPAAEIVKREDPRGATIYWLGANGVPVDASEGTDFYALAHNYVSVTPIQAD
MTAHYSIQALKDTF

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=252, Percent_Identity=51.1904761904762, Blast_Score=253, Evalue=9e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_ACTP2 (A3N3M1)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054612.1
- ProteinModelPortal:   A3N3M1
- SMR:   A3N3M1
- STRING:   A3N3M1
- GeneID:   4849446
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1927
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- PhylomeDB:   A3N3M1
- ProtClustDB:   PRK00346
- BioCyc:   APLE416269:APL_1927-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 27424; Mature: 27424

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILISNDDGYHAQGIQTLAETLRDAGHSVTVIAPDRNRSAASSCLTLMEPIRVHQLDEF
CEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEECCC
NYAVIAGTPADCVHLALNGFFEQSFDLVISGINHGANLGDDVVYSGTVAAALEGRHLPYP
CEEEEECCCHHHHHHHHHHHHHHCHHHEEECCCCCCCCCCCEEECCEEEEEECCCCCCCC
SLAISLVGRKSEGHLFGNNHFDTAAKVVLDLLPKVQKGIVPARQILNINVPDLPYEQVKG
CEEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCHHHHCC
VMITRLGHRSPAAEIVKREDPRGATIYWLGANGVPVDASEGTDFYALAHNYVSVTPIQAD
EEEEECCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCEEEEEEEEC
MTAHYSIQALKDTF
CEEEEEEEEHHCCC
>Mature Secondary Structure
MNILISNDDGYHAQGIQTLAETLRDAGHSVTVIAPDRNRSAASSCLTLMEPIRVHQLDEF
CEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEECCC
NYAVIAGTPADCVHLALNGFFEQSFDLVISGINHGANLGDDVVYSGTVAAALEGRHLPYP
CEEEEECCCHHHHHHHHHHHHHHCHHHEEECCCCCCCCCCCEEECCEEEEEECCCCCCCC
SLAISLVGRKSEGHLFGNNHFDTAAKVVLDLLPKVQKGIVPARQILNINVPDLPYEQVKG
CEEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCHHHHCC
VMITRLGHRSPAAEIVKREDPRGATIYWLGANGVPVDASEGTDFYALAHNYVSVTPIQAD
EEEEECCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCEEEEEEEEC
MTAHYSIQALKDTF
CEEEEEEEEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA