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The map label for this gene is dnaQ [H]

Identifier: 126208748

GI number: 126208748

Start: 1473144

End: 1473917

Strand: Reverse

Name: dnaQ [H]

Synonym: APL_1282

Alternate gene names: 126208748

Gene position: 1473917-1473144 (Counterclockwise)

Preceding gene: 126208749

Following gene: 126208746

Centisome position: 64.8

GC content: 44.19

Gene sequence:

>774_bases
ATGAGTGAACAACCGATAGTAAGACAGGTGGTGCTGGATACCGAAACAACCGGTATGAGTTTTAGCGGACCACCGCAAAT
TGGACATAATATTATTGAAATCGGTGCGGTCGAAGTGATTAATCGTCGCTTAACCGGCCGTACTTTTCACGTCTATATTA
AACCGCCGCGAGAAGTGGATGAAGAGGCGATTAAAGTTCACGGCATTACCAATGAGTTTTTGCAAGATAAGCCTGTGTTT
GCCGAAGTTGCGGACGAATTTATTGAATTTATTAAAGGTGCAGAGCTAATCATTCATAATGCCCCCTTCGACGTGGCATT
TATGGATCAAGAGTTTTCTTATTTGGGAAACCCACCGCCGAAGACGGCTGAAATGTGCAGTGTGACCGATAGTCTTGCGG
TCGCTCGAAAAATGTACCCGGGCAAGCGTAATAACTTAGATGCATTGTGCGACCGTTTAGGCATTGATAACAGCAAGCGT
GTACTTCACGGGGCGTTACTGGATGCGGAGATTCTGGCTGATGTATTCTTGATGATGACTGGCGGACAGCTGGCGTTATT
AGGCGAAGAAGATGCAACCGCTACTCATGAAAATGTTGCGGATCTCGGTTTAGGTACGATAACGAAGTTTGAAACAAGCG
GTTTAATTGTGTTATCTCTGAGTGAAGAAGAGCAAACGGCACACGAAGAATATCTCAAACTGATTGATAAAAAATCTAAG
GGGAATTGTATTTGGATGCGCTCGAATGAAATGGAATCGGAGCAAATTCACTAA

Upstream 100 bases:

>100_bases
GTATTGCGAAGTAATACGTGAATAAGCGGTCGGATTTTAGTGAAAATTTGCAAATTTTCCTTGAAATTCGACCGCTTGCA
TCTTTTGATTAGGCAATAAA

Downstream 100 bases:

>100_bases
TTGCTTGATTTATTTGATTTTAAAATAAGCAAATAAATTCGTTTCGTGAAAAATTGTTTGACGGTTGCGGTATAAATCCG
TATGATTCGGATTACCAGTT

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSEQPIVRQVVLDTETTGMSFSGPPQIGHNIIEIGAVEVINRRLTGRTFHVYIKPPREVDEEAIKVHGITNEFLQDKPVF
AEVADEFIEFIKGAELIIHNAPFDVAFMDQEFSYLGNPPPKTAEMCSVTDSLAVARKMYPGKRNNLDALCDRLGIDNSKR
VLHGALLDAEILADVFLMMTGGQLALLGEEDATATHENVADLGLGTITKFETSGLIVLSLSEEEQTAHEEYLKLIDKKSK
GNCIWMRSNEMESEQIH

Sequences:

>Translated_257_residues
MSEQPIVRQVVLDTETTGMSFSGPPQIGHNIIEIGAVEVINRRLTGRTFHVYIKPPREVDEEAIKVHGITNEFLQDKPVF
AEVADEFIEFIKGAELIIHNAPFDVAFMDQEFSYLGNPPPKTAEMCSVTDSLAVARKMYPGKRNNLDALCDRLGIDNSKR
VLHGALLDAEILADVFLMMTGGQLALLGEEDATATHENVADLGLGTITKFETSGLIVLSLSEEEQTAHEEYLKLIDKKSK
GNCIWMRSNEMESEQIH
>Mature_256_residues
SEQPIVRQVVLDTETTGMSFSGPPQIGHNIIEIGAVEVINRRLTGRTFHVYIKPPREVDEEAIKVHGITNEFLQDKPVFA
EVADEFIEFIKGAELIIHNAPFDVAFMDQEFSYLGNPPPKTAEMCSVTDSLAVARKMYPGKRNNLDALCDRLGIDNSKRV
LHGALLDAEILADVFLMMTGGQLALLGEEDATATHENVADLGLGTITKFETSGLIVLSLSEEEQTAHEEYLKLIDKKSKG
NCIWMRSNEMESEQIH

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=243, Percent_Identity=59.6707818930041, Blast_Score=285, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 28543; Mature: 28412

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQPIVRQVVLDTETTGMSFSGPPQIGHNIIEIGAVEVINRRLTGRTFHVYIKPPREVD
CCCCCCHHHHEECCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHC
EEAIKVHGITNEFLQDKPVFAEVADEFIEFIKGAELIIHNAPFDVAFMDQEFSYLGNPPP
HHHEEEECCHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCHHHHCCCCCC
KTAEMCSVTDSLAVARKMYPGKRNNLDALCDRLGIDNSKRVLHGALLDAEILADVFLMMT
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
GGQLALLGEEDATATHENVADLGLGTITKFETSGLIVLSLSEEEQTAHEEYLKLIDKKSK
CCEEEEECCCCCCCCHHHHHHHCCCCEEEECCCCEEEEEECCHHHHHHHHHHHHHCCCCC
GNCIWMRSNEMESEQIH
CCEEEEECCCCCCCCCC
>Mature Secondary Structure 
SEQPIVRQVVLDTETTGMSFSGPPQIGHNIIEIGAVEVINRRLTGRTFHVYIKPPREVD
CCCCCHHHHEECCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHC
EEAIKVHGITNEFLQDKPVFAEVADEFIEFIKGAELIIHNAPFDVAFMDQEFSYLGNPPP
HHHEEEECCHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCHHHHCCCCCC
KTAEMCSVTDSLAVARKMYPGKRNNLDALCDRLGIDNSKRVLHGALLDAEILADVFLMMT
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
GGQLALLGEEDATATHENVADLGLGTITKFETSGLIVLSLSEEEQTAHEEYLKLIDKKSK
CCEEEEECCCCCCCCHHHHHHHCCCCEEEECCCCEEEEEECCHHHHHHHHHHHHHCCCCC
GNCIWMRSNEMESEQIH
CCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]