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The map label for this gene is clpX [H]

Identifier: 126208745

GI number: 126208745

Start: 1470422

End: 1471681

Strand: Reverse

Name: clpX [H]

Synonym: APL_1279

Alternate gene names: 126208745

Gene position: 1471681-1470422 (Counterclockwise)

Preceding gene: 126208746

Following gene: 126208744

Centisome position: 64.7

GC content: 43.41

Gene sequence:

>1260_bases
ATGGCAAATTTCGAGAAAGAACCGCATTGTAGTTTTTGTGGTAAAAGACGTACCGAAGTTGATCAACTGGTAGAAGGTAC
GGAAGGTTATATCTGTAATCACTGTATTGAAGAGTCTTACGCATTGTTAAACGGCGAAGAAGAACCGTTAATCGATGAAA
AACAGGATGAACAGAAGTTTTTTGAAAATGTGCCGACGCCACACGAGATCAATGCGCATTTAGATGAGTATGTTATCGGT
CAAGAGCATGCGAAAAAAGTGTTGTCCGTAGCGGTTTATAACCACTATAAACGTTTACGTAACGCGCTTTCCGGTCATAA
AGAAACCAACGGCGTAGAGTTGGGTAAAAGTAACATTTTATTAATCGGCCCGACCGGTAGCGGTAAAACCTTATTGGCGG
AAACGTTAGCGCGCCGTTTAAACGTACCCTTTGCGGTTGCGGATGCAACCACGCTGACGCAAGCCGGTTATGTCGGTGAA
GACGTAGAAAACGTGATTCAAAAATTACTGATGAAATGTGATTTTGATGCGGAACAAGCGGAACGCGGTATCGTCTTTAT
TGATGAGATTGACAAAATTACCCGTAAGTCGGAAAGCCCGTCGATTACCCGCGACGTATCCGGTGAAGGCGTGCAACAGG
CGTTATTAAAATTAATCGAAGGCACGGTAGCGAATATCAACCCGCAAGGCAGCCGTAAGCACCCGAAAGGCGAAACGATT
CCGGTCGATACCTCTAAAATCCTCTTTATTTGCGGCGGAGCGTTTGCCGGTTTAGATAAGATTGTCGAGGCTCGTAGTAA
CAAGCAAGGCGGAATCGGTTTTGGCGCAGAATTGAAAAAAGATAAAGAACGTGAAGATCTCACCGAGTTATTCAAACAAG
TTGAGCCGGAAGACTTGGTTAAATTCGGTTTAATTCCGGAGCTTATCGGTCGATTACCGGTTGTGACTCCGTTACAAGAA
CTGGATGAAGAAGCGTTAATTCAAATTTTAACCGAACCGAAAAATGCGATTATCAAGCAATATCAAGCATTATTCCAAAT
GGAAGGTGTTGAGCTGAAATTTACCAAAGAGGCGTTAATTGCAATCGCGCAGAAATCTATTTCACGCAAAACCGGTGCAC
GCGGTTTACGCTCGATTGTTGAGAATCTACTGTTAGATACGATGTATAACTTGCCGACACTTAAAGCAGAGAAAAATGTG
AAAAAAGTGACGGTTGGCAAAGGTTGTGTTGAAAACGGCGATAAGCCGAAAGTAGAGTAA

Upstream 100 bases:

>100_bases
AAGTGGCGGCGGATACTGAGCGAGATAATTTTATGTCGGCGGTTGAAGCGATGGAATACGGTCTAATTGATAAAGTTTTA
ACGCACAGAGATATGAAATA

Downstream 100 bases:

>100_bases
GCATCGCTAAAATGGACAATGTTCTTCATTGTCCATTTGTTTTATCTGTAGGCATCGCCGTTACGCAAACGATAGTATCT
TTAAAGAAATTATATGAATA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MANFEKEPHCSFCGKRRTEVDQLVEGTEGYICNHCIEESYALLNGEEEPLIDEKQDEQKFFENVPTPHEINAHLDEYVIG
QEHAKKVLSVAVYNHYKRLRNALSGHKETNGVELGKSNILLIGPTGSGKTLLAETLARRLNVPFAVADATTLTQAGYVGE
DVENVIQKLLMKCDFDAEQAERGIVFIDEIDKITRKSESPSITRDVSGEGVQQALLKLIEGTVANINPQGSRKHPKGETI
PVDTSKILFICGGAFAGLDKIVEARSNKQGGIGFGAELKKDKEREDLTELFKQVEPEDLVKFGLIPELIGRLPVVTPLQE
LDEEALIQILTEPKNAIIKQYQALFQMEGVELKFTKEALIAIAQKSISRKTGARGLRSIVENLLLDTMYNLPTLKAEKNV
KKVTVGKGCVENGDKPKVE

Sequences:

>Translated_419_residues
MANFEKEPHCSFCGKRRTEVDQLVEGTEGYICNHCIEESYALLNGEEEPLIDEKQDEQKFFENVPTPHEINAHLDEYVIG
QEHAKKVLSVAVYNHYKRLRNALSGHKETNGVELGKSNILLIGPTGSGKTLLAETLARRLNVPFAVADATTLTQAGYVGE
DVENVIQKLLMKCDFDAEQAERGIVFIDEIDKITRKSESPSITRDVSGEGVQQALLKLIEGTVANINPQGSRKHPKGETI
PVDTSKILFICGGAFAGLDKIVEARSNKQGGIGFGAELKKDKEREDLTELFKQVEPEDLVKFGLIPELIGRLPVVTPLQE
LDEEALIQILTEPKNAIIKQYQALFQMEGVELKFTKEALIAIAQKSISRKTGARGLRSIVENLLLDTMYNLPTLKAEKNV
KKVTVGKGCVENGDKPKVE
>Mature_418_residues
ANFEKEPHCSFCGKRRTEVDQLVEGTEGYICNHCIEESYALLNGEEEPLIDEKQDEQKFFENVPTPHEINAHLDEYVIGQ
EHAKKVLSVAVYNHYKRLRNALSGHKETNGVELGKSNILLIGPTGSGKTLLAETLARRLNVPFAVADATTLTQAGYVGED
VENVIQKLLMKCDFDAEQAERGIVFIDEIDKITRKSESPSITRDVSGEGVQQALLKLIEGTVANINPQGSRKHPKGETIP
VDTSKILFICGGAFAGLDKIVEARSNKQGGIGFGAELKKDKEREDLTELFKQVEPEDLVKFGLIPELIGRLPVVTPLQEL
DEEALIQILTEPKNAIIKQYQALFQMEGVELKFTKEALIAIAQKSISRKTGARGLRSIVENLLLDTMYNLPTLKAEKNVK
KVTVGKGCVENGDKPKVE

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=328, Percent_Identity=51.8292682926829, Blast_Score=312, Evalue=3e-85,
Organism=Escherichia coli, GI1786642, Length=408, Percent_Identity=64.9509803921569, Blast_Score=530, Evalue=1e-152,
Organism=Escherichia coli, GI1790366, Length=222, Percent_Identity=34.2342342342342, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=291, Percent_Identity=46.7353951890034, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=291, Percent_Identity=46.7353951890034, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=405, Percent_Identity=39.7530864197531, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=265, Percent_Identity=41.1320754716981, Blast_Score=177, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=415, Percent_Identity=42.6506024096386, Blast_Score=291, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24648291, Length=302, Percent_Identity=48.3443708609272, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24648289, Length=302, Percent_Identity=48.3443708609272, Blast_Score=293, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46362; Mature: 46230

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANFEKEPHCSFCGKRRTEVDQLVEGTEGYICNHCIEESYALLNGEEEPLIDEKQDEQKF
CCCCCCCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
FENVPTPHEINAHLDEYVIGQEHAKKVLSVAVYNHYKRLRNALSGHKETNGVELGKSNIL
HHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEE
LIGPTGSGKTLLAETLARRLNVPFAVADATTLTQAGYVGEDVENVIQKLLMKCDFDAEQA
EEECCCCCHHHHHHHHHHHCCCCEEECCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHH
ERGIVFIDEIDKITRKSESPSITRDVSGEGVQQALLKLIEGTVANINPQGSRKHPKGETI
CCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCC
PVDTSKILFICGGAFAGLDKIVEARSNKQGGIGFGAELKKDKEREDLTELFKQVEPEDLV
CCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCHHHHH
KFGLIPELIGRLPVVTPLQELDEEALIQILTEPKNAIIKQYQALFQMEGVELKFTKEALI
HHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEHHHHHH
AIAQKSISRKTGARGLRSIVENLLLDTMYNLPTLKAEKNVKKVTVGKGCVENGDKPKVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHCCCCCCCCC
>Mature Secondary Structure 
ANFEKEPHCSFCGKRRTEVDQLVEGTEGYICNHCIEESYALLNGEEEPLIDEKQDEQKF
CCCCCCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
FENVPTPHEINAHLDEYVIGQEHAKKVLSVAVYNHYKRLRNALSGHKETNGVELGKSNIL
HHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEE
LIGPTGSGKTLLAETLARRLNVPFAVADATTLTQAGYVGEDVENVIQKLLMKCDFDAEQA
EEECCCCCHHHHHHHHHHHCCCCEEECCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHH
ERGIVFIDEIDKITRKSESPSITRDVSGEGVQQALLKLIEGTVANINPQGSRKHPKGETI
CCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCC
PVDTSKILFICGGAFAGLDKIVEARSNKQGGIGFGAELKKDKEREDLTELFKQVEPEDLV
CCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCHHHHH
KFGLIPELIGRLPVVTPLQELDEEALIQILTEPKNAIIKQYQALFQMEGVELKFTKEALI
HHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEHHHHHH
AIAQKSISRKTGARGLRSIVENLLLDTMYNLPTLKAEKNVKKVTVGKGCVENGDKPKVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA