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The map label for this gene is ndh [H]

Identifier: 126208737

GI number: 126208737

Start: 1460158

End: 1461444

Strand: Direct

Name: ndh [H]

Synonym: APL_1271

Alternate gene names: 126208737

Gene position: 1460158-1461444 (Clockwise)

Preceding gene: 126208736

Following gene: 126208741

Centisome position: 64.2

GC content: 44.13

Gene sequence:

>1287_bases
ATGACAATCGAAACAATCGTTGTAGTCGGCGGCGGTGCAGGCGGTTTAGAGCTTGCGACTTACCTCGGCGACAAATTAGG
TCGTAAGAAAAAATCGAAAGTGATTCTTATCGACCGTAATACGACTCACCTTTGGAAACCTTTGTTACACGAAGTGGCAA
CCGGTTCTTTAGATGAAGGCATCGATGCGCTTAGCTATCGTGCGCATGCCAAAAATCATGCTTTCGAGTTTCAACAAGGG
ACTTTAACGTCGGTTAATCGTGATAAAAAAGAAATCACGCTTGCACCGATTTATAACGAACAGAATCAGTTATTGGTTAA
AGAACGTCATATCGCTTACGATAAATTAGTGATTGCGATCGGCAGTAAATCGAACGATTTCAATACCAAAGGCGTAGCGG
AACACTGCATTTTCTTAGATGGTTCGGAGCAAGCGAAGCAATTCCAAAAACGTATGATGGAATTATTCTTACATTTCTCG
CACAGCGAAGATCAAGATGTAAAAATTGCGATCGTCGGCGGTGGTGCAACCGGTATCGAACTTTCCGCCGAGCTTTATAA
TACGGTTAAACATTTAAACGAATACGGTTTCGGTAAATTACACCGAGCCAGTTTGAAAGTGACGTTAATCGAAGCGGGTC
CTCGTTTAATTCCGGCATTAACCGAAAAAGTATCCGCTTCGGCTTTAGCGGAATTGCGCAAAGCCGGCGTGGACGTTCGT
TTAAATACGATGATTACCGAAGCGGTGGAAGACGGCTTAATCACCAAAGACGGCGAAAAAATTGAAGCCAATCTGATGGT
TTGGGCGGCAGGGATTAAAGCGCCCGAGTTTGTCAAGGAATTCGGTTTTGAAACTAATCGTCTCAACCAAATTGAAATCA
AAGAAACCTTACAAACCACGGTAGATGATTCGGTATATGTTATCGGCGATTGCGCCTCATTAATCCAAGACGGCAAAGCG
ATTCCGCCGCGTGCGCAAGCGGCACACCAAATGGCTACCCAATGCGGTAAAAACATTGTTGCCTTACTTGAAGGCAAAGA
GCAAAAACCGTTTAAATTCAATGATAAAGGCTCTCTGCTTTCGTTCTCTCATTTCGGCACGGTCGGTAACTTGATGGGTA
ACTTAATGAGCGGCGATATGTTTATCGAAGGTAAAATCGCACGCCTTGCATACCTCTCTCTATATCGTATGCACCAAGTC
GCTTTACACGGCTGGGTAAAAACCGCTCTGATTTTATTCGTCGGTCAAATTAACCGCTTCCTCAGACCGTCAATGAAGTT
ACACTAA

Upstream 100 bases:

>100_bases
CAAAATAACCTTAAAAGATACTGGACTTTATTGTTCAAGCGCCTAAAATTAACCCAAATTTTTTGACTTTTATCAATTTA
TTATCTTTTGGAGTATTGCA

Downstream 100 bases:

>100_bases
GCAAAACAAGCGGTTATATTTCCGCAAGATTTTGCAAAAAATTAACCACGGAATACACAGATTACTCGGAAATTTTATTC
GGTGTAATTAGTGTGTTCCG

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTIETIVVVGGGAGGLELATYLGDKLGRKKKSKVILIDRNTTHLWKPLLHEVATGSLDEGIDALSYRAHAKNHAFEFQQG
TLTSVNRDKKEITLAPIYNEQNQLLVKERHIAYDKLVIAIGSKSNDFNTKGVAEHCIFLDGSEQAKQFQKRMMELFLHFS
HSEDQDVKIAIVGGGATGIELSAELYNTVKHLNEYGFGKLHRASLKVTLIEAGPRLIPALTEKVSASALAELRKAGVDVR
LNTMITEAVEDGLITKDGEKIEANLMVWAAGIKAPEFVKEFGFETNRLNQIEIKETLQTTVDDSVYVIGDCASLIQDGKA
IPPRAQAAHQMATQCGKNIVALLEGKEQKPFKFNDKGSLLSFSHFGTVGNLMGNLMSGDMFIEGKIARLAYLSLYRMHQV
ALHGWVKTALILFVGQINRFLRPSMKLH

Sequences:

>Translated_428_residues
MTIETIVVVGGGAGGLELATYLGDKLGRKKKSKVILIDRNTTHLWKPLLHEVATGSLDEGIDALSYRAHAKNHAFEFQQG
TLTSVNRDKKEITLAPIYNEQNQLLVKERHIAYDKLVIAIGSKSNDFNTKGVAEHCIFLDGSEQAKQFQKRMMELFLHFS
HSEDQDVKIAIVGGGATGIELSAELYNTVKHLNEYGFGKLHRASLKVTLIEAGPRLIPALTEKVSASALAELRKAGVDVR
LNTMITEAVEDGLITKDGEKIEANLMVWAAGIKAPEFVKEFGFETNRLNQIEIKETLQTTVDDSVYVIGDCASLIQDGKA
IPPRAQAAHQMATQCGKNIVALLEGKEQKPFKFNDKGSLLSFSHFGTVGNLMGNLMSGDMFIEGKIARLAYLSLYRMHQV
ALHGWVKTALILFVGQINRFLRPSMKLH
>Mature_427_residues
TIETIVVVGGGAGGLELATYLGDKLGRKKKSKVILIDRNTTHLWKPLLHEVATGSLDEGIDALSYRAHAKNHAFEFQQGT
LTSVNRDKKEITLAPIYNEQNQLLVKERHIAYDKLVIAIGSKSNDFNTKGVAEHCIFLDGSEQAKQFQKRMMELFLHFSH
SEDQDVKIAIVGGGATGIELSAELYNTVKHLNEYGFGKLHRASLKVTLIEAGPRLIPALTEKVSASALAELRKAGVDVRL
NTMITEAVEDGLITKDGEKIEANLMVWAAGIKAPEFVKEFGFETNRLNQIEIKETLQTTVDDSVYVIGDCASLIQDGKAI
PPRAQAAHQMATQCGKNIVALLEGKEQKPFKFNDKGSLLSFSHFGTVGNLMGNLMSGDMFIEGKIARLAYLSLYRMHQVA
LHGWVKTALILFVGQINRFLRPSMKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=430, Percent_Identity=60.4651162790698, Blast_Score=518, Evalue=1e-148,
Organism=Saccharomyces cerevisiae, GI6323515, Length=461, Percent_Identity=24.5119305856833, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323794, Length=352, Percent_Identity=26.1363636363636, Blast_Score=83, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6320118, Length=364, Percent_Identity=25.2747252747253, Blast_Score=73, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47226; Mature: 47095

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIETIVVVGGGAGGLELATYLGDKLGRKKKSKVILIDRNTTHLWKPLLHEVATGSLDEG
CCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHC
IDALSYRAHAKNHAFEFQQGTLTSVNRDKKEITLAPIYNEQNQLLVKERHIAYDKLVIAI
HHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCCEEHHHHHCCEEEEEEEE
GSKSNDFNTKGVAEHCIFLDGSEQAKQFQKRMMELFLHFSHSEDQDVKIAIVGGGATGIE
CCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEE
LSAELYNTVKHLNEYGFGKLHRASLKVTLIEAGPRLIPALTEKVSASALAELRKAGVDVR
EHHHHHHHHHHHHHCCCCCEEECEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
LNTMITEAVEDGLITKDGEKIEANLMVWAAGIKAPEFVKEFGFETNRLNQIEIKETLQTT
EHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHCCCCCCCCEEEHHHHHHHH
VDDSVYVIGDCASLIQDGKAIPPRAQAAHQMATQCGKNIVALLEGKEQKPFKFNDKGSLL
CCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCEE
SFSHFGTVGNLMGNLMSGDMFIEGKIARLAYLSLYRMHQVALHGWVKTALILFVGQINRF
EEHHHCCHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRPSMKLH
HCCCCCCC
>Mature Secondary Structure 
TIETIVVVGGGAGGLELATYLGDKLGRKKKSKVILIDRNTTHLWKPLLHEVATGSLDEG
CEEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHC
IDALSYRAHAKNHAFEFQQGTLTSVNRDKKEITLAPIYNEQNQLLVKERHIAYDKLVIAI
HHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCCEEHHHHHCCEEEEEEEE
GSKSNDFNTKGVAEHCIFLDGSEQAKQFQKRMMELFLHFSHSEDQDVKIAIVGGGATGIE
CCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEE
LSAELYNTVKHLNEYGFGKLHRASLKVTLIEAGPRLIPALTEKVSASALAELRKAGVDVR
EHHHHHHHHHHHHHCCCCCEEECEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
LNTMITEAVEDGLITKDGEKIEANLMVWAAGIKAPEFVKEFGFETNRLNQIEIKETLQTT
EHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHCCCCCCCCEEEHHHHHHHH
VDDSVYVIGDCASLIQDGKAIPPRAQAAHQMATQCGKNIVALLEGKEQKPFKFNDKGSLL
CCCCEEEEECHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCEE
SFSHFGTVGNLMGNLMSGDMFIEGKIARLAYLSLYRMHQVALHGWVKTALILFVGQINRF
EEHHHCCHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRPSMKLH
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]